Reubi, Jean-Claude; Waser, Beatrice; Cescato, Renzo; Gloor, Beat; Stettler, Christoph; Christ, Emanuel (2010). Internalized somatostatin receptor subtype 2 in neuroendocrine tumors of octreotide-treated patients. Journal of clinical endocrinology and metabolism, 95(5), pp. 2343-50. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2009-2487
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Somatostatin receptor subtype 2 (sst(2)) is widely expressed in neuroendocrine tumors and can be visualized immunohistochemically at the cell membrane for diagnostic purposes. Recently, it has been demonstrated in animal sst(2) tumor models in vivo that somatostatin analog treatment was able to induce a complete internalization of the tumor sst(2).
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery 04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition |
UniBE Contributor: |
Reubi-Kattenbusch, Jean-Claude, Waser, Beatrice, Cescato, Renzo, Gloor, Beat, Stettler, Christoph, Christ, Emanuel |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
0021-972X |
Publisher: |
Endocrine Society |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:08 |
Last Modified: |
12 Oct 2023 15:26 |
Publisher DOI: |
10.1210/jc.2009-2487 |
PubMed ID: |
20228164 |
Web of Science ID: |
000277356700045 |
BORIS DOI: |
10.48350/355 |
URI: |
https://boris.unibe.ch/id/eprint/355 (FactScience: 197699) |