Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607

Ocak, Meltem; Helbok, Anna; Rangger, Christine; Peitl, Petra Kolenc; Nock, Berthold A; Morelli, Giancarlo; Eek, Annemarie; Sosabowski, Jane K; Breeman, Wout A P; Reubi, Jean-Claude; Decristoforo, Clemens (2011). Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1426-35. Berlin: Springer 10.1007/s00259-011-1818-9

Full text not available from this repository. (Request a copy)

Stability of radiolabelled cholecystokinin 2 (CCK2) receptor targeting peptides has been a major limitation in the use of such radiopharmaceuticals especially for targeted radionuclide therapy applications, e.g. for treatment of medullary thyroid carcinoma (MTC). The purpose of this study was to compare the in vitro stability of a series of peptides binding to the CCK2 receptor [selected as part of the COST Action on Targeted Radionuclide Therapy (BM0607)] and to identify major cleavage sites.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Reubi-Kattenbusch, Jean-Claude

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

1619-7070

Publisher:

Springer

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:18

Last Modified:

14 Oct 2019 16:33

Publisher DOI:

10.1007/s00259-011-1818-9

PubMed ID:

21528387

Web of Science ID:

000292272700004

URI:

https://boris.unibe.ch/id/eprint/5559 (FactScience: 210313)

Actions (login required)

Edit item Edit item
Provide Feedback