Laverman, Peter; Joosten, Lieke; Eek, Annemarie; Roosenburg, Susan; Peitl, Petra Kolenc; Maina, Theodosia; Mäcke, Helmut; Aloj, Luigi; von Guggenberg, Elisabeth; Sosabowski, Jane K; de Jong, Marion; Reubi, Jean-Claude; Oyen, Wim J G; Boerman, Otto C (2011). Comparative biodistribution of 12 ¹¹¹In-labelled gastrin/CCK2 receptor-targeting peptides. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1410-6. Berlin: Springer 10.1007/s00259-011-1806-0
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Laverman2011_Article_ComparativeBiodistributionOf12.pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial (CC-BY-NC). Download (479kB) | Preview |
Cholecystokinin 2 (CCK-2) receptor overexpression has been demonstrated in various tumours such as medullary thyroid carcinomas and small-cell lung cancers. Due to this high expression, CCK-2 receptors might be suitable targets for radionuclide imaging and/or radionuclide therapy. Several CCK-2 receptor-binding radiopeptides have been developed and some have been tested in patients. Here we aimed to compare the in vivo tumour targeting properties of 12 (111)In-labelled 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)-conjugated gastrin/CCK2 receptor-binding peptides.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Reubi-Kattenbusch, Jean-Claude |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
1619-7070 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:18 |
Last Modified: |
05 Dec 2022 14:05 |
Publisher DOI: |
10.1007/s00259-011-1806-0 |
PubMed ID: |
21461732 |
Web of Science ID: |
000292272700002 |
BORIS DOI: |
10.48350/5561 |
URI: |
https://boris.unibe.ch/id/eprint/5561 (FactScience: 210315) |
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