Lactate dehydrogenase concentration in nasal wash fluid indicates severity of rhinovirus-induced wheezy bronchitis in preschool children.

Cangiano, Giulia; Proietti, Elena; Kronig, Marie Noelle; Kieninger, Elisabeth; Sadeghi, Christine D; Gorgievski, Meri; Barbani, Maria Teresa; Midulla, Fabio; Tapparel, Caroline; Kaiser, Laurent; Alves, Marco P; Regamey, Nicolas (2014). Lactate dehydrogenase concentration in nasal wash fluid indicates severity of rhinovirus-induced wheezy bronchitis in preschool children. The Pediatric infectious disease journal, 33(12), pp. 1285-1287. Lippincott Williams & Wilkins 10.1097/INF.0000000000000420

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The clinical course of rhinovirus (RV)-associated wheezing illnesses is difficult to predict. We measured lactate dehydrogenase concentrations, RV load, antiviral and proinflammatory cytokines in nasal washes obtained from 126 preschool children with RV wheezy bronchitis. lactate dehydrogenase values were inversely associated with subsequent need for oxygen therapy. lactate dehydrogenase may be a useful biomarker predicting disease severity in RV wheezy bronchitis.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Kieninger, Elisabeth; Gorgievski, Meri; Barbani, Maria Teresa and Regamey, Nicolas

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology

ISSN:

1532-0987

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Meri Gorgievski

Date Deposited:

01 Jun 2015 11:53

Last Modified:

01 Nov 2016 13:26

Publisher DOI:

10.1097/INF.0000000000000420

PubMed ID:

25389710

BORIS DOI:

10.7892/boris.69252

URI:

https://boris.unibe.ch/id/eprint/69252

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