Reubi, Jean Claude; Erchegyi, Judit; Cescato, Renzo; Waser, Beatrice; Rivier, Jean E (2010). Switch from antagonist to agonist after addition of a DOTA chelator to a somatostatin analog. European journal of nuclear medicine and molecular imaging, 37(8), pp. 1551-8. Berlin: Springer-Verlag 10.1007/s00259-010-1445-x
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Peptide receptor targeting has become an increasingly attractive method to target tumors diagnostically and radiotherapeutically. Peptides linked to a variety of chelators have been developed for this purpose. They have, however, rarely been tested for their agonistic or antagonistic properties. We report here on a somatostatin antagonist that switched to an agonist upon coupling to a DOTA chelator.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Reubi-Kattenbusch, Jean-Claude, Cescato, Renzo, Waser, Beatrice |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
1619-7070 |
Publisher: |
Springer-Verlag |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:08 |
Last Modified: |
05 Dec 2022 14:00 |
Publisher DOI: |
10.1007/s00259-010-1445-x |
PubMed ID: |
20396884 |
Web of Science ID: |
000280639400014 |
BORIS DOI: |
10.7892/boris.710 |
URI: |
https://boris.unibe.ch/id/eprint/710 (FactScience: 200444) |
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