Effect of boundary conditions on yield properties of human femoral trabecular bone

Panyasantisuk, Jarunan; Pahr, Dieter; Zysset, Philippe (2016). Effect of boundary conditions on yield properties of human femoral trabecular bone. Biomechanics and Modeling in Mechanobiology, 15(5), pp. 1043-1053. Springer 10.1007/s10237-015-0741-6

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Trabecular bone plays an important mechanical role in bone fractures and implant stability. Homogenized nonlinear finite element (FE) analysis of whole bones can deliver improved fracture risk and implant loosening assessment. Such simulations require the knowledge of mechanical properties such as an appropriate yield behavior and criterion for trabecular bone. Identification of a complete yield surface is extremely difficult experimentally but can be achieved in silico by using micro-FE analysis on cubical trabecular volume elements. Nevertheless, the influence of the boundary conditions (BCs), which are applied to such volume elements, on the obtained yield properties remains unknown. Therefore, this study compared homogenized yield properties along 17 load cases of 126 human femoral trabecular cubic specimens computed with classical kinematic uniform BCs (KUBCs) and a new set of mixed uniform BCs, namely periodicity-compatible mixed uniform BCs (PMUBCs). In stress space, PMUBCs lead to 7–72 % lower yield stresses compared to KUBCs. The yield surfaces obtained with both KUBCs and PMUBCs demonstrate a pressure-sensitive ellipsoidal shape. A volume fraction and fabric-based quadric yield function successfully fitted the yield surfaces of both BCs with a correlation coefficient R2≥0.93. As expected, yield strains show only a weak dependency on bone volume fraction and fabric. The role of the two BCs in homogenized FE analysis of whole bones will need to be investigated and validated with experimental results at the whole bone level in future studies.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute for Surgical Technology & Biomechanics ISTB

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Panyasantisuk, Jarunan and Zysset, Philippe

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health
600 Technology > 620 Engineering

ISSN:

1617-7940

Publisher:

Springer

Funders:

[4] Swiss National Science Foundation

Projects:

[508] Inclusion of cortex and fabric in QCT-based patient-specific finite element analysis of the proximal femur

Language:

English

Submitter:

Jarunan Panyasantisuk

Date Deposited:

09 Feb 2016 11:51

Last Modified:

06 Jun 2017 17:23

Publisher DOI:

10.1007/s10237-015-0741-6

PubMed ID:

26517986

BORIS DOI:

10.7892/boris.75248

URI:

https://boris.unibe.ch/id/eprint/75248

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