Christ, Emanuel; Wild, Damian; Reubi, Jean-Claude (2010). Glucagonlike peptide-1 receptor: an example of translational research in insulinomas: a review. Endocrinology and metabolism clinics of North America, 39(4), pp. 791-800. Philadelphia, Pa.: Elsevier 10.1016/j.ecl.2010.09.003
Full text not available from this repository.Glucagonlike peptide-1 receptors (GLP-1R) play an increasingly important role in endocrine gastrointestinal tumor management. In particular, virtually all benign insulinomas express GLP-1R in high density. Exendin-4 is a GLP-1 analog that has a longer half-life than GLP-1. Targeting GLP-1R by (111)In-DOTA-exendin-4 or (111)In-DPTA-exendin-4 offers a new approach that permits the successful localization of small benign insulinomas. It is likely that this new noninvasive technique has the potential to replace the invasive localization by selective arterial stimulation and venous sampling.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology 04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition |
UniBE Contributor: |
Christ, Emanuel, Reubi-Kattenbusch, Jean-Claude |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
0889-8529 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:09 |
Last Modified: |
05 Dec 2022 14:00 |
Publisher DOI: |
10.1016/j.ecl.2010.09.003 |
PubMed ID: |
21095545 |
Web of Science ID: |
000285850800009 |
URI: |
https://boris.unibe.ch/id/eprint/791 (FactScience: 200863) |
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