Distribution pattern of 68Ga-DOTATATE in disease-free patients

Shastry, Manu; Kayani, Irfan; Wild, Damian; Caplin, Martyn; Visvikis, Dimitris; Gacinovic, Svetislav; Reubi, Jean-Claude; Bomanji, Jamshed B (2010). Distribution pattern of 68Ga-DOTATATE in disease-free patients. Nuclear medicine communications, 31(12), pp. 1025-32. London: Lippincott Williams & Wilkins 10.1097/MNM.0b013e32833f635e

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68Ga-DOTA-DPhe1,Tyr3-octreotate (68Ga-DOTATATE) is a somatostatin analogue that shows high affinity for somatostatin receptor subtype 2 (sst2) and has been used for imaging neuroendocrine tumours. However, normal uptake patterns and potential pitfalls have not been described with this high-sensitivity radiotracer. The aim of this study was therefore to outline the normal distribution pattern of 68Ga-DOTATATE in disease-free patients, to provide standardized uptake values (SUVs) of various organs and to compare our results with the current knowledge on sst2 receptor expression in vitro.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Reubi-Kattenbusch, Jean-Claude

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

0143-3636

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:09

Last Modified:

14 Oct 2019 17:00

Publisher DOI:

10.1097/MNM.0b013e32833f635e

PubMed ID:

20926978

Web of Science ID:

000284443800005

URI:

https://boris.unibe.ch/id/eprint/792 (FactScience: 200864)

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