Spicher, Martin; Röthlisberger, Carole; Lany, C.; Lundström-Stadelmann, Britta; Keiser, J.; Ortega-Mora, L. M.; Gottstein, Bruno; Hemphill, Andrew (2008). In Vitro and In Vivo Treatments of Echinococcus Protoscoleces and Metacestodes with Artemisinin and Artemisinin Derivatives. Antimicrobial agents and chemotherapy, 52(9), pp. 3447-3450. American Society for Microbiology 10.1128/AAC.00553-08
Full text not available from this repository.In vitro treatment of Echinococcus multilocularis and Echinococcus granulosus larval stages with the antimalarials dihydroartemisinin and artesunate (10 to 40 microM) exhibited promising results, while 6 weeks of in vivo treatment of mice infected with E. multilocularis metacestodes (200 mg/kg of body weight/day) had no effect. However, combination treatments of both drugs with albendazole led to a substantial but statistically not significant reduction in parasite weight compared to results with albendazole alone
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Parasitology 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) |
Graduate School: |
Graduate School for Cellular and Biomedical Sciences (GCB) |
UniBE Contributor: |
Spicher, Martin, Röthlisberger, Carole, Lundström Stadelmann, Britta, Gottstein, Bruno, Hemphill, Andrew |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 630 Agriculture |
ISSN: |
0066-4804 |
Publisher: |
American Society for Microbiology |
Language: |
German |
Submitter: |
Britta Lundström Stadelmann |
Date Deposited: |
20 Jul 2017 16:27 |
Last Modified: |
05 Dec 2022 14:56 |
Publisher DOI: |
10.1128/AAC.00553-08 |
PubMed ID: |
18625777 |
URI: |
https://boris.unibe.ch/id/eprint/82055 |
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