Spicher, Martin; Röthlisberger, Carole; Lany, C.; Lundström-Stadelmann, Britta; Keiser, J.; Ortega-Mora, L. M.; Gottstein, Bruno; Hemphill, Andrew (2008). In Vitro and In Vivo Treatments of Echinococcus Protoscoleces and Metacestodes with Artemisinin and Artemisinin Derivatives. Antimicrobial agents and chemotherapy, 52(9), pp. 3447-3450. American Society for Microbiology 10.1128/AAC.00553-08
Full text not available from this repository. (Request a copy)In vitro treatment of Echinococcus multilocularis and Echinococcus granulosus larval stages with the antimalarials dihydroartemisinin and artesunate (10 to 40 microM) exhibited promising results, while 6 weeks of in vivo treatment of mice infected with E. multilocularis metacestodes (200 mg/kg of body weight/day) had no effect. However, combination treatments of both drugs with albendazole led to a substantial but statistically not significant reduction in parasite weight compared to results with albendazole alone
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Parasitology 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) |
Graduate School: |
Graduate School for Cellular and Biomedical Sciences (GCB) |
UniBE Contributor: |
Spicher, Martin, Röthlisberger, Carole, Lundström Stadelmann, Britta, Gottstein, Bruno, Hemphill, Andrew |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 630 Agriculture |
ISSN: |
0066-4804 |
Publisher: |
American Society for Microbiology |
Language: |
German |
Submitter: |
Britta Lundström Stadelmann |
Date Deposited: |
20 Jul 2017 16:27 |
Last Modified: |
05 Dec 2022 14:56 |
Publisher DOI: |
10.1128/AAC.00553-08 |
PubMed ID: |
18625777 |
URI: |
https://boris.unibe.ch/id/eprint/82055 |
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