Effect of cytomix and sedative drugs on mitochondrial electron transport chain of cultured primary human astrocytes

Bhaskar, Monica; Jakob, Stephan; Djafarzadeh, Siamak (2 November 2016). Effect of cytomix and sedative drugs on mitochondrial electron transport chain of cultured primary human astrocytes (Unpublished). In: Day of Clinical Research 2016.

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Septic shock is a major cause of death among patients in intensive care units worldwide. Despite the recent developments and progression in medical research, sepsis remains a challenge. Multiple‐organ failure including brain dysfunction (septic encephalopathy) is the predominant cause of death in septic patients. Elevations of cytokine concentrations in the brain have been described in both experimental and clinical studies. Furthermore, mitochondrial dysfunction has also been described in septic encephalopathy. Since also sedative drugs interfere with brain function, they may contribute to septic encephalopathy.

Item Type:

Conference or Workshop Item (Poster)

Division/Institute:

04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic of Intensive Care

UniBE Contributor:

Bhaskar, Monica; Jakob, Stephan and Djafarzadeh, Siamak

Subjects:

600 Technology > 610 Medicine & health

Language:

English

Submitter:

Mirella Aeberhard

Date Deposited:

09 Jan 2017 13:31

Last Modified:

09 Jan 2017 13:31

BORIS DOI:

10.7892/boris.90603

URI:

https://boris.unibe.ch/id/eprint/90603

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