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Wyss, Rahel Kathrin; Méndez Carmona, Natalia; Sanz-Garcia, Maria Nieves; Arnold, Maria Regula; Segiser, Adrian; Fiedler, Georg Martin; Carrel, Thierry; Djafarzadeh, Siamak; Tevaearai, Hendrik; Henning Longnus, Sarah (2019). Mitochondrial integrity during early reperfusion in an isolated rat heart model of donation after circulatory death-consequences of ischemic duration. Journal of heart and lung transplantation, 38(6), pp. 647-657. Elsevier 10.1016/j.healun.2018.12.013
Werner Möller, Per; Hana, Anisa; Heinisch, Paul Philipp; Liu, Shengchen; Djafarzadeh, Siamak; Hänggi, Matthias; Bloch, Andreas; Takala, Jukka; Jakob, Stephan; Berger, David (2019). The Effects of Vasoconstriction and Volume Expansion on Veno-Arterial ECMO Flow. Shock, 51(5), pp. 650-658. Lippincott Williams & Wilkins 10.1097/SHK.0000000000001197
Corrêa, Thiago Domingos; Pereira, Adriano José; Brandt, Sebastian; Vuda, Madhusudanarao; Djafarzadeh, Siamak; Takala, Jukka; Jakob, Stephan (2017). Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis. Critical care, 21(1), p. 105. BioMed Central 10.1186/s13054-017-1691-4
Djafarzadeh, Siamak; Jakob, Stephan (2017). Isolation of Intact Mitochondria from Skeletal Muscle by Differential Centrifugation for High-resolution Respirometry Measurements. Journal of visualized experiments(121) MYJoVE Corporation 10.3791/55251
Djafarzadeh, Siamak; Jakob, Stephan (2017). High-resolution Respirometry to Assess Mitochondrial Function in Permeabilized and Intact Cells. Journal of visualized experiments(120) MYJoVE Corporation 10.3791/54985
Merz, Tobias; Pereira, Adriano J; Schürch, Roger; Schefold, Joerg C.; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2017). Mitochondrial function of immune cells in septic shock: A prospective observational cohort study. PLoS ONE, 12(6), e0178946. Public Library of Science 10.1371/journal.pone.0178946
Bhaskar, Monica; Jakob, Stephan; Djafarzadeh, Siamak (2 November 2016). Effect of cytomix and sedative drugs on mitochondrial electron transport chain of cultured primary human astrocytes (Unpublished). In: Day of Clinical Research 2016.
Djafarzadeh, Siamak; Vuda, Madhusudanarao; Jeger, Victor; Takala, Jukka; Jakob, Stephan (2016). The Effects of Fentanyl on Hepatic Mitochondrial Function. Anesthesia and analgesia, 123(2), pp. 311-325. International Anesthesia Research Society 10.1213/ANE.0000000000001280
Merz, Tobias Michael; Pichler Hefti, Jacqueline Renée; Hefti, Urs; Huber, Andreas; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2015). Changes in mitochondrial enzymatic activities of monocytes during prolonged hypobaric hypoxia and influence of antioxidants: A randomized controlled study. Redox report, 20(5), pp. 234-240. Maney Publishing 10.1179/1351000215Y.0000000007
Jeger, Victor; Brandt, Sebastian; Porta, Francesca; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2015). Dose response of endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed research international, 2015, p. 353074. Hindawi Publishing Corporation 10.1155/2015/353074
Pereira, A. J.; Jeger, V.; Fahrner, R.; Djafarzadeh, Siamak; Lensch, Michael; Takala, Jukka; Jakob, Stephan (2014). Interference of angiotensin II and enalapril with hepatic blood flow regulation. American journal of physiology - gastrointestinal and liver physiology, 307(6), G655-G663. American Physiological Society 10.1152/ajpgi.00150.2014
Corrêa, Thiago D.; Jeger, Victor; Pereira, Adriano José; Takala, Jukka; Djafarzadeh, Siamak; Jakob, Stephan (2014). Angiotensin II in Septic Shock: effects on tissue perfusion, organ function, and mitochondrial respiration in a porcine model of fecal peritonitis. Critical care medicine, 42(8), e550-e559. Lippincott Williams & Wilkins 10.1097/CCM.0000000000000397
Ackermann, Karin; Bostock, Hugh; Brander, Lukas; Schröder, Ralph; Djafarzadeh, Siamak; Tuchscherer, Daniel; Jakob, Stephan; Takala, Jukka; Z'Graggen, Werner Josef (2014). Early changes of muscle membrane properties in porcine faecal peritonitis. Critical care, 18(4), p. 484. BioMed Central 10.1186/s13054-014-0484-2
Gorrasi, José; Eleftheriadis, Anestis; Takala, Jukka; Brandt, Sebastian; Djafarzadeh, Siamak; Brügger, Lukas; Bracht, Hendrik; Jakob, Stephan (2013). Different Contribution of Splanchnic Organs to Hyperlactatemia in Fecal Peritonitis and Cardiac Tamponade. BioMed research international, 2013, pp. 1-8. Hindawi Publishing Corporation 10.1155/2013/251084
Astin, Ronan; Bentham, Robert; Djafarzadeh, Siamak; Horscroft, James A.; Kuc, Rhoda E.; Leung, Po Sing; Skipworth, James R. A.; Vicencio, Jose M.; Davenport, Anthony P.; Murray, Andrew J.; Takala, Jukka; Jakob, Stephan; Montgomery, Hugh; Szabadkai, Gyorgy (2013). No evidence for a local renin-angiotensin system in liver mitochondria. Scientific Reports, 3(1), p. 2467. Nature Publishing Group 10.1038/srep02467
Jeger, Victor; Djafarzadeh, Siamak; Jakob, Stephan; Takala, Jukka (2013). Mitochondrial function in sepsis. European journal of clinical investigation, 43(5), pp. 532-542. Wiley-Blackwell 10.1111/eci.12069
Corrêa, Thiago Domingos; Vuda, Madhusudanarao; Takala, Jukka; Djafarzadeh, Siamak; Silva, Eliézer; Jakob, Stephan (2013). Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function. Critical care, 17(1), R21. BioMed Central 10.1186/cc12495
Vuda, Madhusudanarao; Brander, Lukas; Schröeder, Ralph; Jakob, Stephan M; Takala, Jukka; Djafarzadeh, Siamak (2012). Effects of catecholamines on hepatic and skeletal muscle mitochondrial respiration after prolonged exposure to faecal peritonitis in pigs. Innate immunity, 18(2), pp. 217-30. Los Angeles, Calif.: Sage Publications 10.1177/1753425911398279
Chiusa, Manuel; Hool, Sara-Lynn; Truetsch, Petra; Djafarzadeh, Siamak; Jakob, Stephan M; Seifriz, Franziska; Scherer, Stefan J; Suter, Thomas M; Zuppinger, Christian; Zbinden, Stephan (2012). Cancer therapy modulates VEGF signaling and viability in adult rat cardiac microvascular endothelial cells and cardiomyocytes. Journal of molecular and cellular cardiology, 52(5), pp. 1164-75. Oxford: Elsevier 10.1016/j.yjmcc.2012.01.022
Corrêa, Thiago D; Vuda, Madhusudanarao; Blaser, Annika Reintam; Takala, Jukka; Djafarzadeh, Siamak; Dünser, Martin W; Silva, Eliézer; Lensch, Michael; Wilkens, Ludwig; Jakob, Stephan M (2012). Effect of treatment delay on disease severity and need for resuscitation in porcine fecal peritonitis. Critical care medicine, 40(10), pp. 2841-9. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0b013e31825b916b
Regueira, T; Djafarzadeh, S; Brandt, S; Gorrasi, J; Borotto, E; Porta, F; Takala, J; Bracht, H; Shaw, S; Lepper, P M; Jakob, S M (2012). Oxygen transport and mitochondrial function in porcine septic shock, cardiogenic shock, and hypoxaemia. Acta anaesthesiologica Scandinavica, 56(7), pp. 846-59. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2012.02706.x
Shafighi, Maziar; Olariu, Radu; Brun, Claudio; Fathi, Ali R; Djafarzadeh, Siamak; Jakob, Stephan M; Hunger, Robert E; Banic, Andrej; Constantinescu, Mihai A (2012). The role of androgens on hypoxia-inducible factor (HIF)-1α-induced angiogenesis and on the survival of ischemically challenged skin flaps in a rat model. Microsurgery, 32(6), pp. 475-81. New York, N.Y.: Wiley-Liss 10.1002/micr.21996
Djafarzadeh, Siamak; Vuda, Madhusudanarao; Takala, Jukka; Jakob, Stephan M (2012). Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes. PLoS ONE, 7(9), e45195. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0045195
Djafarzadeh, Siamak; Vuda, Madhusudanarao; Takala, Jukka; Ochs, Matthias; Jakob, Stephan M (2011). Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes. Mitochondrion, 11(1), pp. 83-8. Amsterdam: Elsevier 10.1016/j.mito.2010.07.010
Shafighi, Maziar; Olariu, Radu; Fathi, Ali R; Djafarzadeh, Siamak; Jakob, Stephan M; Banic, Andrej; Constantinescu, Mihai A (2011). Dimethyloxalylglycine stabilizes HIF-1α in cultured human endothelial cells and increases random-pattern skin flap survival in vivo. Plastic and reconstructive surgery, 128(2), pp. 415-422. Lippincott Williams & Wilkins 10.1097/PRS.0b013e31821e6e69
Spirig, Rolf; Djafarzadeh, Siamak; Regueira, Tomas; Shaw, Sidney G; von Garnier, Christophe; Takala, Jukka; Jakob, Stephan M; Rieben, Robert; Lepper, Philipp M (2010). Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditions. PLoS ONE, 5(6), e0010983. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0010983
Brandt, S; Regueira, T; Bracht, H; Porta, F; Takala, J; Hiltebrand, LB; Beldi, G; Lepper, MP; Brügger, LE; Kessler, U; Jakob St, M (2009). Effect of fluid resuscitation on mortality and organ function in experimental sepsis models. Critical care, 13(6), R186. London: BioMed Central 10.1186/cc8179
Regueira, T; Andresen, M; Djafarzadeh, S (2009). [Mitochondrial dysfunction during sepsis, impact and possible regulating role of hypoxia-inducible factor-1alpha]. Medicina intensiva, 33(8), pp. 385-92. Madrid: IDEPSA, International de Ediciones y Publicaciones, S.A. 10.1016/j.medin.2008.10.002
Regueira, Tomas; Lepper, Philipp M; Brandt, Sebastian; Ochs, Matthias; Vuda, Madhusudanarao; Takala, Jukka; Jakob, Stephan M; Djafarzadeh, Siamak (2009). Hypoxia inducible factor-1 alpha induction by tumour necrosis factor-alpha, but not by toll-like receptor agonists, modulates cellular respiration in cultured human hepatocytes. Liver international, 29(10), pp. 1582-92. Oxford: Blackwell Munksgaard 10.1111/j.1478-3231.2009.02109.x
Regueira, Tomas; Bänziger, Bertram; Djafarzadeh, Siamak; Brandt, Sebastian; Gorrasi, Jose; Takala, Jukka; Lepper, Philipp M; Jakob, Stephan M (2008). Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration. Critical care, 12(4), R88. London: BioMed Central 10.1186/cc6956
Regueira, Tomas Emilio; Jakob, Stephan; Djafarzadeh, Siamak (2008). Regulation of mitochondrial function by hypoxia and inflammation in sepsis: A putative role for hypoxia inducible factor. In: Vincent, Jean-Louis (ed.) Yearbook of Intensive Care and Emergency Medicine 2008 (pp. 385-394). Heidelberg: Springer 10.1007/978-3-540-77290-3_36
