HIV-Positive-to-HIV-Positive Liver Transplantation.

Calmy, A; van Delden, C; Giostra, E; Junet, C; Rubbia Brandt, L; Yerly, S; Chave, J-P; Samer, C; Elkrief, L; Vionnet, J; Beldi, Guido; Huynh-Do, Uyen; Stirnimann, Guido; Berney, T; Swiss Transplant Cohort Study, STCS (2016). HIV-Positive-to-HIV-Positive Liver Transplantation. American journal of transplantation, 16(8), pp. 2473-2478. Wiley-Blackwell 10.1111/ajt.13824

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Most countries exclude human immunodeficiency virus (HIV)-positive patients from organ donation because of concerns regarding donor-derived HIV transmission. The Swiss Federal Act on Transplantation has allowed organ transplantation between HIV-positive donors and recipients since 2007. We report the successful liver transplantation from an HIV-positive donor to an HIV-positive recipient. Both donor and recipient had been treated for many years with antiretroviral therapy and harbored multidrug-resistant viruses. Five months after transplantation, HIV viremia remains undetectable. This observation supports the inclusion of appropriate HIV-positive donors for transplants specifically allocated to HIV-positive recipients.

Item Type:

 Journal Article (Further Contribution)

Division/Institute:

 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Unit Childrens Hospital > Forschungsgruppe Nephrologie / Hypertonie
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Viszeralchirurgie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Viszeralchirurgie
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery

UniBE Contributor:

 Beldi, Guido; Huynh-Do, Uyen and Stirnimann, Guido

Subjects:

 600 Technology > 610 Medicine & health

ISSN:

 1600-6135

Publisher:

 Wiley-Blackwell

Language:

 English

Submitter:

 Lilian Karin Smith-Wirth

Date Deposited:

 10 Feb 2017 14:26

Last Modified:

 12 May 2017 07:45

Publisher DOI:

 10.1111/ajt.13824

PubMed ID:

 27109874

Uncontrolled Keywords:

 clinical research/practice; ethics and public policy; immune deficiency; infectious disease; patient safety

BORIS DOI:

 10.7892/boris.93403

URI:

 https://boris.unibe.ch/id/eprint/93403

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