HIV-Positive-to-HIV-Positive Liver Transplantation.

Calmy, A; van Delden, C; Giostra, E; Junet, C; Rubbia Brandt, L; Yerly, S; Chave, J-P; Samer, C; Elkrief, L; Vionnet, J; Beldi, Guido; Huynh-Do, Uyen; Stirnimann, Guido; Berney, T; Swiss Transplant Cohort Study, STCS (2016). HIV-Positive-to-HIV-Positive Liver Transplantation. American journal of transplantation, 16(8), pp. 2473-2478. Wiley-Blackwell 10.1111/ajt.13824

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Most countries exclude human immunodeficiency virus (HIV)-positive patients from organ donation because of concerns regarding donor-derived HIV transmission. The Swiss Federal Act on Transplantation has allowed organ transplantation between HIV-positive donors and recipients since 2007. We report the successful liver transplantation from an HIV-positive donor to an HIV-positive recipient. Both donor and recipient had been treated for many years with antiretroviral therapy and harbored multidrug-resistant viruses. Five months after transplantation, HIV viremia remains undetectable. This observation supports the inclusion of appropriate HIV-positive donors for transplants specifically allocated to HIV-positive recipients.

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