A new rabbit model for the study of early brain injury after subarachnoid hemorrhage.

Marbacher, Serge; Andereggen, Lukas; Neuschmelting, Volker; Widmer, Hans Rudolf; von Gunten, Michael; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2012). A new rabbit model for the study of early brain injury after subarachnoid hemorrhage. Journal of neuroscience methods, 208(2), pp. 138-145. Amsterdam: Elsevier 10.1016/j.jneumeth.2012.05.010

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Pathophysiological disturbances during subarachnoid hemorrhage (SAH) and within the first few days thereafter are responsible for significant brain damage. Early brain injury (EBI) after SAH has become the focus of current research activities. The purpose of the present study was to evaluate whether a novel rabbit SAH model provokes EBI by means of neuronal degeneration, brain tissue death, and apoptosis in cerebral vascular endothelial cells.

Item Type:

 Journal Article (Original Article)

Division/Institute:

 04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic of Intensive Care
04 Faculty of Medicine > Service Sector > Institute of Pathology
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Mu50 > Forschungsgruppe Neurochirurgie

UniBE Contributor:

 Marbacher, Serge, Andereggen, Lukas, Widmer, Hans Rudolf, von Gunten, Michael, Takala, Jukka, Jakob, Stephan

Subjects:

 500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

 0165-0270

Publisher:

 Elsevier

Language:

 English

Submitter:

 Factscience Import

Date Deposited:

 04 Oct 2013 14:26

Last Modified:

 05 Dec 2022 14:08

Publisher DOI:

 10.1016/j.jneumeth.2012.05.010

PubMed ID:

 22595025

Web of Science ID:

 000306882800007

BORIS DOI:

 10.48350/9667

URI:

 https://boris.unibe.ch/id/eprint/9667 (FactScience: 215435)

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