Classification of Mild Cognitive Impairment and Alzheimer Disease Using Model-Based MR and Magnetization Transfer Imaging

Wiest, R; Burren, Y; Hauf, M; Schroth, G; Pruessner, J; Zbinden, M; Cattapan-Ludewig, K; Kiefer, C (2013). Classification of Mild Cognitive Impairment and Alzheimer Disease Using Model-Based MR and Magnetization Transfer Imaging. American journal of neuroradiology AJNR, 34(4), pp. 740-6. Oak Brook, Ill.: American Society of Neuroradiology 10.3174/ajnr.A3307

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Early stratification of degenerative processes is a prerequisite to warrant therapeutic options in prodromal Alzheimer disease. Our aim was to investigate differences in cerebral macromolecular tissue composition between patients with AD, mild cognitive impairment, and age- and sex-matched healthy controls by using model-based magnetization transfer with a binary spin-bath magnetization transfer model and magnetization transfer ratio at 1.5 T.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology 04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Management
UniBE Contributor:	Wiest, Roland Gerhard Rudi, Burren, Yuliya, Hauf, Martinus, Zbinden, Martin, Cattapan-Ludewig, Katja
ISSN:	0195-6108
Publisher:	American Society of Neuroradiology
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:30
Last Modified:	02 Mar 2023 23:21
Publisher DOI:	10.3174/ajnr.A3307
PubMed ID:	23064592
URI:	https://boris.unibe.ch/id/eprint/11574 (FactScience: 217776)