Mohsen, Mona O.; Speiser, Daniel E; Knuth, Alexander; Bachmann, Martin F. (2020). Virus-like particles for vaccination against cancer. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 12(1), e1579. Wiley 10.1002/wnan.1579
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Virus‐like particles for vaccination against cancer - Mohsen - .pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (6MB) | Preview |
Active immunotherapy of cancer aims to treat the disease by inducing effective cellular and humoral immune responses. Virus-like particle-based vaccines have evolved dramatically over the last few decades, greatly reducing morbidity and mortality of several infectious diseases and expectedly preventing cervical cancer caused by human papilloma virus. In contrast to these broad successes of disease prevention, therapeutic cancer vaccines remain to demonstrate clinical benefit. Yet, several preclinical and clinical trials have revealed promising results and are paving the way for medical breakthroughs. This study reviews and discusses the recent preclinical development and clinical trials in this field. This article is categorized under: Biology-Inspired Nanomaterials > Protein and Virus-Based Structures Nanotechnology Approaches to Biology > Nanoscale Systems in Biology.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie 04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology and Immunology |
UniBE Contributor: |
Mohsen, Mona Omar Mahmoud, Bachmann, Martin (B) |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1939-0041 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Lee-Anne Brand |
Date Deposited: |
15 Nov 2019 16:05 |
Last Modified: |
29 Mar 2023 23:36 |
Publisher DOI: |
10.1002/wnan.1579 |
PubMed ID: |
31456339 |
Uncontrolled Keywords: |
cancer vaccine virus like particles |
BORIS DOI: |
10.7892/boris.135086 |
URI: |
https://boris.unibe.ch/id/eprint/135086 |