Marques, Ines J.; Lupi, Eleonora; Mercader, Nadia (2019). Model systems for regeneration: zebrafish. Development, 146(18) Company of Biologists Limited 10.1242/dev.167692
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Tissue damage can resolve completely through healing and regeneration, or can produce permanent scarring and loss of function. The response to tissue damage varies across tissues and between species. Determining the natural mechanisms behind regeneration in model organisms that regenerate well can help us develop strategies for tissue recovery in species with poor regenerative capacity (such as humans). The zebrafish (Danio rerio) is one of the most accessible vertebrate models to study regeneration. In this Primer, we highlight the tools available to study regeneration in the zebrafish, provide an overview of the mechanisms underlying regeneration in this system and discuss future perspectives for the field.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy 04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy > Functional Anatomy 09 Interdisciplinary Units > Microscopy Imaging Center (MIC) |
Graduate School: |
Graduate School for Cellular and Biomedical Sciences (GCB) |
UniBE Contributor: |
dos Santos Marques, Ines Joao, Lupi, Eleonora, Mercader Huber, Nadia Isabel |
Subjects: |
600 Technology > 610 Medicine & health 500 Science > 570 Life sciences; biology |
ISSN: |
0950-1991 |
Publisher: |
Company of Biologists Limited |
Language: |
English |
Submitter: |
Nadia Isabel Mercader Huber |
Date Deposited: |
20 Nov 2019 11:04 |
Last Modified: |
05 Dec 2022 15:32 |
Publisher DOI: |
10.1242/dev.167692 |
PubMed ID: |
31540899 |
BORIS DOI: |
10.7892/boris.135134 |
URI: |
https://boris.unibe.ch/id/eprint/135134 |
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