Schmid, Robin Michael; Studer, Eveline; Hirsbrunner, Gabriela (2020). [Oestrus suppression in a dairy herd by means of anti-GnRH vaccination Improvac®: A prospective field study]. Schweizer Archiv für Tierheilkunde, 162(2), pp. 93-100. Gesellschaft Schweizer Tierärztinnen und Tierärzte 10.17236/sat00245
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INTRODUCTION
The aim of this study was to evaluate the duration of estrus suppression after a double administration of the anti-GnRH vaccine Improvac® (Zoetis Schweiz GmbH, 2800 Delémont) in cows. Furthermore, it should be investigated, if a third administration could prolong the effect of the cycle suppression. A total of 21 cows (more than four weeks post partum) were vaccinated twice, at least 35 days apart, with 2 ml Improvac® (0.4 mg of a GnRH-analogon) subcutaneously on one side of the neck. Over a period of 368 days and in the course of 18 farm visits these cows were examined gynecologically and re-vaccinated if they showed signs of estrus behaviour or ovarian activity. After the second vaccination the cycle of the cows was suppressed for an average period of 114 days (59-175 days) and the effect could be prolonged by a booster of the vaccine for another 127 days in three cows. Estrus behaviour was absent for a longer period than ovarian activity was. The vaccine was tolerated well: apart from slight swelling at the injection site, no side effects were observed. Our results demonstrate that two immunizations with Improvac® are an easily applicable method for the suppression of cyclic activity in cows for a mean period of 114 days. The duration of cycle suppression was prolonged by a booster of the vaccination.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Clinic for Ruminants 05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) |
UniBE Contributor: |
Schmid, Robin Michael, Studer, Eveline, Hirsbrunner, Gabriela |
Subjects: |
600 Technology > 630 Agriculture 500 Science > 590 Animals (Zoology) 600 Technology > 610 Medicine & health |
ISSN: |
1664-2848 |
Publisher: |
Gesellschaft Schweizer Tierärztinnen und Tierärzte |
Language: |
German |
Submitter: |
Nathalie Viviane Zollinger |
Date Deposited: |
14 Feb 2020 09:06 |
Last Modified: |
05 Dec 2022 15:36 |
Publisher DOI: |
10.17236/sat00245 |
PubMed ID: |
32004139 |
Uncontrolled Keywords: |
Anti-GnRH Brunst Immunisierung Improvac® Rind bovino cattle chaleurs estro immunisation immunizzazione oestrus vaches |
BORIS DOI: |
10.7892/boris.139916 |
URI: |
https://boris.unibe.ch/id/eprint/139916 |