Plate, Andreas; Kronenberg, Andreas; Risch, Martin; Mueller, Yolanda; Di Gangi, Stefania; Rosemann, Thomas; Senn, Oliver (2020). Treatment of urinary tract infections in Swiss primary care: quality and determinants of antibiotic prescribing. BMC family practice, 21(1), p. 125. BioMed Central 10.1186/s12875-020-01201-1
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BACKGROUND
Urinary tract infections are one of the most common reasons for prescribing antibiotics in primary care. Current guidelines recommend fosfomycin, nitrofurantoin, or trimethoprim - sulfamethoxazol as empiric first line antimicrobial agents in uncomplicated infections. However, there is evidence that the use of fluoroquinolones, which are no longer recommended, is still inappropriate high. We determined antibiotic prescription patterns, quality and factors affecting antibiotic prescriptions in urinary tract infections in primary care in Switzerland.
METHODS
From June 2017 to August 2018, we conducted a cross-sectional study in patients suffering from a urinary tract infection (UTI). Patient and general practitioners characteristics as well as antibiotic prescribing patterns were analysed.
RESULTS
Antibiotic prescribing patterns in 1.352 consecutively recruited patients, treated in 163 practices could be analysed. In 950 (84.7%) patients with an uncomplicated UTI the prescriptions were according to current guidelines and therefore rated as appropriate. Fluoroquinolones were prescribed in 13.8% and therefore rated as inappropriate. In multivariable analysis, the age of the general practitioner was associated with increasing odds of prescribing a not guideline recommended antibiotic therapy.
CONCLUSIONS
We found a high degree of guideline conform antibiotic prescriptions in patients with an uncomplicated urinary tract infection in primary care in Switzerland. However, there is still a substantial use of fluoroquinolones in empiric therapy.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases |
UniBE Contributor: |
Kronenberg, Andreas Oskar |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
1471-2296 |
Publisher: |
BioMed Central |
Language: |
English |
Submitter: |
Andreas Oskar Kronenberg |
Date Deposited: |
12 Nov 2020 11:31 |
Last Modified: |
05 Dec 2022 15:41 |
Publisher DOI: |
10.1186/s12875-020-01201-1 |
PubMed ID: |
32611320 |
Uncontrolled Keywords: |
Antibiotic prescribing quality Primary care Quality indicator Switzerland Urinary tract infection |
BORIS DOI: |
10.7892/boris.147819 |
URI: |
https://boris.unibe.ch/id/eprint/147819 |