Autheman, Delphine; Sheldon, R Ann; Chaudhuri, Nondini; von Arx, Sebastian; Siegenthaler, Corinne; Ferriero, Donna M; Christen, Stephan (2012). Glutathione peroxidase overexpression causes aberrant ERK activation in neonatal mouse cortex after hypoxic preconditioning. Pediatric research, 72(6), pp. 568-75. New York, N.Y.: Nature Publishing Group 10.1038/pr.2012.124
Full text not available from this repository.Preconditioning of neonatal mice with nonlethal hypoxia (HPC) protects the brain from hypoxic-ischemic (HI) injury. Overexpression of human glutathione peroxidase 1 (GPx1), which normally protects the developing murine brain from HI injury, reverses HPC protection, suggesting that a certain threshold of hydrogen peroxide concentration is required for activation of HPC signaling.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases |
UniBE Contributor: |
Christen, Stephan |
ISSN: |
0031-3998 |
Publisher: |
Nature Publishing Group |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:38 |
Last Modified: |
05 Dec 2022 14:11 |
Publisher DOI: |
10.1038/pr.2012.124 |
PubMed ID: |
23007029 |
Web of Science ID: |
000312518900003 |
URI: |
https://boris.unibe.ch/id/eprint/15177 (FactScience: 222442) |
Actions (login required)
 |
Edit item |