Ostinelli, Edoardo Giuseppe; Efthimiou, Orestis; Naci, Huseyin; Furukawa, Toshi A; Leucht, Stefan; Salanti, Georgia; Wainwright, Laurence; Zangani, Caroline; De Crescenzo, Franco; Smith, Katharine; Stevens, Katherine; Liu, Qiang; Cipriani, Andrea (2022). Vitruvian plot: a visualisation tool for multiple outcomes in network meta-analysis. Evidence-Based Mental Health, 25(e1), e65-e70. BMJ Publishing Group 10.1136/ebmental-2022-300457
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OBJECTIVE
A network meta-analysis (NMA) usually assesses multiple outcomes across several treatment comparisons. The Vitruvian plot aims to facilitate communication of multiple outcomes from NMAs to patients and clinicians.
METHODS
We developed this tool following the recommendations on the communication of benefit-risk information from the available literature. We collected and implemented feedback from researchers, statisticians, methodologists, clinicians and people with lived experience of physical and mental health issues.
RESULTS
We present the Vitruvian plot, which graphically presents absolute estimates and relative performance of competing interventions against a common comparator for several outcomes of interest. We use two alternative colour schemes to highlight either the strength of statistical evidence or the confidence in the evidence. Confidence in the evidence is evaluated across six domains (within-study bias, reporting bias, indirectness, imprecision, heterogeneity and incoherence) using the Confidence in Network Meta-Analysis (CINeMA) system.
CONCLUSIONS
The Vitruvian plot allows reporting of multiple outcomes from NMAs, with colourings appropriate to inform credibility of the presented evidence.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM) 04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM) |
UniBE Contributor: |
Efthimiou, Orestis, Salanti, Georgia |
Subjects: |
600 Technology > 610 Medicine & health 300 Social sciences, sociology & anthropology > 360 Social problems & social services |
ISSN: |
1362-0347 |
Publisher: |
BMJ Publishing Group |
Funders: |
[4] Swiss National Science Foundation |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
27 May 2022 08:04 |
Last Modified: |
21 Dec 2022 12:24 |
Publisher DOI: |
10.1136/ebmental-2022-300457 |
PubMed ID: |
35613849 |
Uncontrolled Keywords: |
PSYCHIATRY |
BORIS DOI: |
10.48350/170266 |
URI: |
https://boris.unibe.ch/id/eprint/170266 |
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