Performance of the Dexcom G6 Continuous Glucose Monitoring (CGM) System During Cardiac Surgery Using Hypothermic Extracorporeal Circulation.

Herzig, David; Vettoretti, Martina; Guensch, Dominik P; Melmer, Andreas; Schürch, Daniel; Roos, Jonathan; Goerg, Arna M C; Krutkyte, Gabija; Cecchini, Luca; Facchinetti, Andrea; Vogt, Andreas P; Bally, Lia (2023). Performance of the Dexcom G6 Continuous Glucose Monitoring (CGM) System During Cardiac Surgery Using Hypothermic Extracorporeal Circulation. Diabetes care, 46(4), pp. 864-867. American Diabetes Association 10.2337/dc22-2260

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BACKGROUND

Continuous glucose monitoring (CGM) may be challenged by extreme conditions during cardiac surgery using hypothermic extracorporeal circulation (ECC).

RESEARCH DESIGN AND METHODS

We evaluated the Dexcom G6 sensor in 16 subjects undergoing cardiac surgery with hypothermic ECC, of whom 11 received deep hypothermic circulatory arrest (DHCA). Arterial blood glucose, quantified by the Accu-Chek Inform II meter, served as reference.

RESULTS

Intrasurgery mean absolute relative difference (MARD) of 256 paired CGM/reference values was 23.8%. MARD was 29.1% during ECC (154 pairs) and 41.6% immediately after DHCA (10 pairs), with a negative bias (signed relative difference: -13.7%, -26.6%, and -41.6%). During surgery, 86.3% pairs were in Clarke error grid zones A or B and 41.0% of sensor readings fulfilled the International Organization for Standardization (ISO) 15197:2013 norm. Postsurgery, MARD was 15.0%.

CONCLUSIONS

Cardiac surgery using hypothermic ECC challenges the accuracy of the Dexcom G6 CGM although recovery appears to occur thereafter.

Item Type:

 Journal Article (Original Article)

Division/Institute:

 04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy > Partial clinic Insel
04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition

Graduate School:

 Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

 Herzig, David, Günsch, Dominik, Melmer, Andreas, Goerg, Arna Marie Catherine, Krutkyte, Gabija, Vogt, Andreas, Bally, Lia Claudia

Subjects:

 600 Technology > 610 Medicine & health

ISSN:

 0149-5992

Publisher:

 American Diabetes Association

Language:

 English

Submitter:

 Pubmed Import

Date Deposited:

 23 Feb 2023 11:31

Last Modified:

 06 Apr 2023 09:08

Publisher DOI:

 10.2337/dc22-2260

PubMed ID:

 36809308

BORIS DOI:

 10.48350/179049

URI:

 https://boris.unibe.ch/id/eprint/179049

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