TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system

Rindi, G; Kloppel, G; Alhman, H; Caplin, M; Couvelard, A; de Herder, WW; Erikssson, B; Falchetti, A; Falconi, M; Komminoth, P; Koerner, M; Lopes, JM; McNicol, AM; Nilsson, O; Perren, A; Scarpa, A; Scoazec, JY; Wiedenmann, B (2006). TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system. Virchows Archiv, 449(4), pp. 395-401. Berlin: Springer 10.1007/s00428-006-0250-1

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The need for standards in the management of patients with endocrine tumors of the digestive system prompted the European Neuroendocrine Tumor Society (ENETS) to organize a first Consensus Conference, which was held in Frascati (Rome) and was based on the recently published ENETS guidelines on the diagnosis and treatment of digestive neuroendocrine tumors (NET). Here, we report the tumor–node–metastasis proposal for foregut NETs of the stomach, duodenum, and pancreas that was designed, discussed, and consensually approved at this conference. In addition, we report the proposal for a working formulation for the grading of digestive NETs based on mitotic count and Ki-67 index. This proposal, which needs to be validated, is meant to help clinicians in the stratification, treatment, and follow-up of patients.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Körner Jachertz, Meike

ISSN:

0945-6317

Publisher:

Springer

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:48

Last Modified:

05 Dec 2022 14:15

Publisher DOI:

10.1007/s00428-006-0250-1

Web of Science ID:

000240723800001

BORIS DOI:

10.48350/20306

URI:

https://boris.unibe.ch/id/eprint/20306 (FactScience: 3562)

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