Lurman, Glenn; Koschnick, Nils; Pörtner, Hans-O; Lucassen, Magnus (2007). Molecular characterisation and expression of Atlantic cod (Gadus morhua) myoglobin from two populations held at two different acclimation temperatures. Comparative biochemistry and physiology. Part A - molecular & integrative physiology, 148(3), pp. 681-689. Elsevier 10.1016/j.cbpa.2007.08.021
Full text not available from this repository. (Request a copy)Much previous research has demonstrated the plasticity of myoglobin concentrations in both cardiac and skeletal myocytes in response to hypoxia and training. No study has yet looked at the effect of thermal acclimation on myoglobin in fish. Atlantic cod (Gadus morhua) from two different populations, i.e. the North Sea and the North East Arctic, were acclimated to 10 and 4 degrees C. Both the myoglobin mRNA and myoglobin protein in cod hearts increased significantly by up to 3.7 and 2.3 fold respectively as a result of acclimation to 4 degrees C. These increments were largest in the Arctic population, which in earlier studies have been shown to possess cold compensated metabolic demands at low temperatures. These metabolic demands associated with higher mitochondrial capacities may have driven the increase in cardiac myoglobin concentrations, in order to support diffusive oxygen supply. At the same time the increase in myoglobin levels may serve further functions during cold acclimation, for example, protection of the cell against reactive oxygen species, and scavenging nitric oxide, thereby contributing to the regulation of mitochondrial volume density.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy > Functional Anatomy |
UniBE Contributor: |
Lurman, Glenn |
Subjects: |
500 Science > 590 Animals (Zoology) |
ISSN: |
1095-6433 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Glenn Lurman |
Date Deposited: |
11 Jul 2014 11:39 |
Last Modified: |
05 Dec 2022 14:31 |
Publisher DOI: |
10.1016/j.cbpa.2007.08.021 |
PubMed ID: |
17884647 |
URI: |
https://boris.unibe.ch/id/eprint/46885 |
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