The Interactions of Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases

Perazzo, Hugo; Poynard, Thierry; Dufour, Jean-François; Dufour, Jean-François (2014). The Interactions of Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases. Clinics in Liver Disease, 18(1), pp. 233-248. Elsevier 10.1016/j.cld.2013.09.014

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A complex interaction among metabolic factors, adipose tissue lipolysis, oxidative stress, and insulin resistance results in a deleterious process that may link nonalcoholic fatty liver disease (NAFLD) with severe cardiovascular (CV) outcomes. Patients with NAFLD are at higher risk of atherosclerosis, new onset of CV events, and overall mortality. The strong association between NAFLD and CV disease should affect clinical practice, with screening and surveillance of patients with NAFLD. This review discusses the data linking these major diseases.

Item Type:

 Journal Article (Review Article)

Division/Institute:

 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

 Dufour, Jean-François, Dufour, Jean-François

Subjects:

 600 Technology > 610 Medicine & health

ISSN:

 1089-3261

Publisher:

 Elsevier

Language:

 English

Submitter:

 Lilian Karin Smith-Wirth

Date Deposited:

 22 Apr 2015 08:36

Last Modified:

 05 Dec 2022 14:35

Publisher DOI:

 10.1016/j.cld.2013.09.014

PubMed ID:

 24274877

Uncontrolled Keywords:

 Atherosclerosis; Cardiovascular disease; Insulin resistance; Liver fibrosis; Nonalcoholic fatty liver disease

BORIS DOI:

 10.7892/boris.53726

URI:

 https://boris.unibe.ch/id/eprint/53726

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