Schlapbach, C; Zawodniak, A; Irla, N; Adam, J; Hunger, R E; Yerly, D; Pichler, W J; Yawalkar, N (2011). NKp46+ cells express granulysin in multiple cutaneous adverse drug reactions. Allergy, 66(11), pp. 1469-76. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02677.x
Full text not available from this repository. (Request a copy)The spectrum of cutaneous adverse drug reactions (cADRs) ranges from benign presentations to severe life-threatening forms such as toxic epidermal necrolysis (TEN). In TEN, granulysin has been shown to be the key cytotoxic molecule. Still, little is known about the expression of granulysin in other cADRs. As an important source of granulysin, natural killer (NK) cells are of major interest in cADRs. Recently, NKp46 has been identified as the most selective NK-cell marker. However, the role of NKp46(+) cells in cADRs and their contribution to granulysin expression remain to be elucidated.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology 04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology |
UniBE Contributor: |
Schlapbach, Christoph, Irla, Nathalie, Hunger, Robert, Pichler, Werner Joseph, Yawalkar, Nikhil |
ISSN: |
0105-4538 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:21 |
Last Modified: |
05 Dec 2022 14:06 |
Publisher DOI: |
10.1111/j.1398-9995.2011.02677.x |
PubMed ID: |
21819408 |
Web of Science ID: |
000296046100011 |
URI: |
https://boris.unibe.ch/id/eprint/7069 (FactScience: 212219) |
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