Comparison of the diagnostic significance of clinical, radiographic and ultrasonographic results after an experimental aerosol infection of pigs with Actinobacillus pleuropneumoniae

Höltig, D; Hennig-Pauka, I; Beyerbach, M; Thies, K; Rehm, T; Gerlach, G-F; Waldmann, K-H; FUGATO-Konsortium, IRAS (2008). Comparison of the diagnostic significance of clinical, radiographic and ultrasonographic results after an experimental aerosol infection of pigs with Actinobacillus pleuropneumoniae. Berliner und Münchener tierärztliche Wochenschrift, 121(11-12), pp. 422-431. Schlütersche 10.2376/0005-9366-121-422

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Scoring schemes for clinical, ultrasonographic and radiographic findings in pigs were developed based upon a standardized animal model for Actinobacillus pleuropneumoniae infection.The results of these methods were compared to each other as well as with the corresponding pathomorphological findings during necropsy. Altogether 69 pigs of different breeding lines (Hampshire, Pietrain and German Landrace were examined. Positive correlations were found between the results of all three methods as well as with the necropsy scores (p <0.0001). Different pathomorphological findings were detected either by radiographic or by ultrasonographic examination dependent upon the type of lung tissue alterations: Alterations of the pleura as well as sequestration of lung tissue on the lung surface could be clearly identified during the ultrasonographic examination while deep tissue alterations with no contact to the lung surface could be detected reliably by radiographic examination. Both methods complement each other, and the application of a combined ultrasonographic and radiographic examination of the thorax allows a comprehensive inspection of the lung condition. Particularly during the acute phase of the disease the extent of lung tissue damage can be estimated more precisely than by clinical examination alone.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Institute of Genetics
05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

Subjects:

500 Science > 590 Animals (Zoology)
600 Technology > 630 Agriculture
500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

0005-9366

Publisher:

Schlütersche

Language:

German

Submitter:

Tosso Leeb

Date Deposited:

14 Aug 2015 14:45

Last Modified:

05 Nov 2019 02:27

Publisher DOI:

10.2376/0005-9366-121-422

PubMed ID:

19086692

Additional Information:

Tosso Leeb ist Mitglied im FUGATO-Konsortium IRAS

BORIS DOI:

10.7892/boris.70779

URI:

https://boris.unibe.ch/id/eprint/70779

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