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Jaume, Guillaume; De Brot, Simone; Song, Andrew H; Williamson, Drew F K; Oldenburg, Lukas; Zhang, Andrew; Chen, Richard J; Asin, Javier; Blatter, Sohvi; Dettwiler, Martina; Goepfert, Christine; Grau-Roma, Llorenç; Soto, Sara; Keller, Stefan M; Rottenberg, Sven; Del-Pozo, Jorge; Pettit, Rowland; Le, Long Phi; Mahmood, Faisal (23 July 2024). Deep Learning-based Modeling for Preclinical Drug Safety Assessment. (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2024.07.20.604430
Patke, Rodhan; Harris, Anna E; Woodcock, Corinne L; Thompson, Rachel; Santos, Rute; Kumari, Amber; Allegrucci, Cinzia; Archer, Nathan; Gudas, Lorraine J; Robinson, Brian D; Persson, Jenny L; Fray, Rupert; Jeyapalan, Jennie; Rutland, Catrin S; Rakha, Emad; Madhusudan, Srinivasan; Emes, Richard D; Muyangwa-Semenova, Musalwa; Alsaleem, Mansour; De Brot, Simone; ... (2024). Epitranscriptomic mechanisms of androgen signalling and prostate cancer. Neoplasia, 56, p. 101032. Elsevier 10.1016/j.neo.2024.101032
Zhang, Lei; Ipaktchi, Ramin; Ben Brahim, Bilal; Arenas Hoyos, Isabel; Jenni, Hansjoerg; Dietrich, Lena; Despont, Alain; Shaw-Boden, Jane; Büttiker, Svenja; Siegrist, David; Gultom, Mitra; Parodi, Chiara; Garcia Casalta, Luisana; Petrucci, Mariafrancesca; Petruccione, Ilaria; Mirra, Alessandro; Nettelbeck, Kay; Wang, Junhua; De Brot, Simone; Vögelin, Esther; ... (2024). Prolongation of the Time Window From Traumatic Limb Amputation to Replantation From 6 to 33 Hours Using Ex Vivo Limb Perfusion. Military medicine, 189(Supplement_3), pp. 83-92. Oxford University Press 10.1093/milmed/usae043
Nißler, Robert; Dennebouy, Lena; Gogos, Alexander; Gerken, Lukas R H; Dommke, Maximilian; Zimmermann, Monika; Pais, Michael A; Neuer, Anna L; Matter, Martin T; Kissling, Vera M; de Brot, Simone; Lese, Ioana; Herrmann, Inge K (2024). Protein Aggregation on Metal Oxides Governs Catalytic Activity and Cellular Uptake. Small, 20(34), e2311115. Wiley-VCH 10.1002/smll.202311115
Jaume, Guillaume; Peeters, Thomas; Song, Andrew H; Pettit, Rowland; Williamson, Drew F K; Oldenburg, Lukas; Vaidya, Anurag; De Brot, Simone; Chen, Richard J; Thiran, Jean-Philippe; Le, Long Phi; Gerber, Georg; Mahmood, Faisal (23 July 2024). AI-driven Discovery of Morphomolecular Signatures in Toxicology. (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2024.07.19.604355
Aeschlimann, Leonore; Kehl, Alexandra; Guscetti, Franco; Posthaus, Caroline; Aupperle-Lellbach, Heike; Rottenberg, Sven; De Brot, Simone (2024). Effective detection of BRAFV595E mutation in canine urothelial and prostate carcinomas using immunohistochemistry. Veterinary and comparative oncology, 22(2), pp. 295-302. Wiley 10.1111/vco.12978
De Brot, Simone; Cobb, Jack; Alibhai, Aziza A; Jackson-Oxley, Jorja; Haque, Maria; Patke, Rodhan; Harris, Anna E; Woodcock, Corinne L; Lothion-Roy, Jennifer; Varun, Dhruvika; Thompson, Rachel; Gomes, Claudia; Kubale, Valentina; Dunning, Mark D; Jeyapalan, Jennie N; Mongan, Nigel P; Rutland, Catrin S (2024). Immunohistochemical Investigation into Protein Expression Patterns of FOXO4, IRF8 and LEF1 in Canine Osteosarcoma. Cancers, 16(10) MDPI AG 10.3390/cancers16101945
Aupperle-Lellbach, Heike; Kehl, Alexandra; De Brot, Simone; van der Weyden, Louise (2024). Clinical Use of Molecular Biomarkers in Canine and Feline Oncology: Current and Future. Veterinary sciences, 11(5) MDPI 10.3390/vetsci11050199
Josi, Romano; Speiser, Daniel E; de Brot, Simone; Vogt, Anne-Cathrine; Sevick-Muraca, Eva M; Tolstonog, Genrich V; Bachmann, Martin F; Mohsen, Mona O (2024). A tetravalent nanovaccine that inhibits growth of HPV-associated head and neck carcinoma via dendritic and T cell activation. iScience, 27(4) Elsevier 10.1016/j.isci.2024.109439
Josi, Romano; Ogrina, Anete; Rothen, Dominik; Balke, Ina; Solé Casaramona, Arnau; de Brot, Simone; Mohsen, Mona O. (2024). Intranodal Injection of Immune Activator Demonstrates Antitumor Efficacy in an Adjuvant Approach. Vaccines, 12(4) MDPI 10.3390/vaccines12040355
Kehl, Alexandra; Aupperle-Lellbach, Heike; De Brot, Simone Danielle; van der Weyden, Louise (2024). Review of Molecular Technologies for Investigating Canine Cancer. Animals, 14(5) MDPI 10.3390/ani14050769
Pais, Michael-Alexander; Papanikolaou, Athanasios; Arenas Hoyos, Isabel; Nißler, Robert; De Brot, Simone; Gogos, Alexander; Rieben, Robert; Constantinescu, Mihai A; Matter, Martin T; Herrmann, Inge K; Lese, Ioana (2024). Bioglass/ceria nanoparticle hybrids for the treatment of seroma: a comparative long-term study in rats. Frontiers in Bioengineering and Biotechnology, 12(1363126) Frontiers Media 10.3389/fbioe.2024.1363126
Petrucci, Mariafrancesca; De Brot, Simone; Casoni, Daniela (2024). Case report: Side effects of etomidate in propylene glycol in five Göttingen Minipigs. Frontiers in veterinary science, 11 Frontiers Media 10.3389/fvets.2024.1376604
Kourouklis, Andreas P; Kaemmel, Julius; Wu, Xi; Baños, Miguel; Chanfon, Astrid; De Brot, Simone; Ferrari, Aldo; Cesarovic, Nikola; Falk, Volkmar; Mazza, Edoardo (2023). Transdermal wires for improved integration in vivo. Biomaterials advances, 153, p. 213568. Elsevier 10.1016/j.bioadv.2023.213568
Nasif, Sofia; Colombo, Martino; Uldry, Anne-Christine; Schröder, Markus S; De Brot, Simone; Mühlemann, Oliver (2023). Inhibition of nonsense-mediated mRNA decay reduces the tumorigenicity of human fibrosarcoma cells. NAR cancer, 5(3), zcad048. Oxford University Press 10.1093/narcan/zcad048
Wong, Kim; Abascal, Federico; Ludwig, Latasha; Aupperle-Lellbach, Heike; Grassinger, Julia; Wright, Colin W; Allison, Simon J; Pinder, Emma; Phillips, Roger M; Romero, Laura P; Gal, Arnon; Roady, Patrick J; Pires, Isabel; Guscetti, Franco; Munday, John S; Peleteiro, Maria C; Pinto, Carlos A; Carvalho, Tânia; Cota, João; Du Plessis, Elizabeth C; ... (2023). Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer. Genome biology, 24(1), p. 191. BioMed Central Ltd. 10.1186/s13059-023-03026-4
Küchler, Leonore; Posthaus, Caroline; Jäger, Kathrin; Guscetti, Franco; van der Weyden, Louise; von Bomhard, Wolf; Schmidt, Jarno M; Farra, Dima; Aupperle-Lellbach, Heike; Kehl, Alexandra; Rottenberg, Sven; de Brot, Simone (2023). Artificial Intelligence to Predict the BRAF V595E Mutation in Canine Urinary Bladder Urothelial Carcinomas. Animals, 13(15) MDPI 10.3390/ani13152404
Hofmann, Martin; Haeberlin, Andreas; de Brot, Simone; Stahel, Andreas; Keppner, Herbert; Burger, Juergen (2023). Development and evaluation of a titanium-based planar ultrasonic scalpel for precision surgery. Ultrasonics, 130, p. 106927. Elsevier 10.1016/j.ultras.2023.106927
Vasciaveo, Alessandro; Arriaga, Juan Martin; Nunes de Almeida, Francisca; Zou, Min; Douglass, Eugene F; Picech, Florencia; Shibata, Maho; Rodriguez-Calero, Antonio; de Brot, Simone; Mitrofanova, Antonina; Chua, Chee Wai; Karan, Charles; Realubit, Ronald; Pampou, Sergey; Kim, Jaime Y; Afari, Stephanie N; Mukhammadov, Timur; Zanella, Luca; Corey, Eva; Alvarez, Mariano J; ... (2023). OncoLoop: A network-based precision cancer medicine framework. Cancer discovery, 13(2), pp. 386-409. American Association for Cancer Research 10.1158/2159-8290.CD-22-0342
Triscott, Joanna; Reist, Matthias; Küng, Lukas; Moselle, Francielle C; Lehner, Marika; Gallon, John; Ravi, Archna; Arora, Gurpreet K; De Brot, Simone; Lundquist, Mark; Gallart-Ayala, Hector; Ivanisevic, Julijana; Piscuoglio, Salvatore; Cantley, Lewis C; Emerling, Brooke M; Rubin, Mark A (2023). PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition. Science Advances, 9(5), eade8641. American Association for the Advancement of Science 10.1126/sciadv.ade8641
Metzler, Veronika M; De Brot, Simone; Haigh, Daisy B; Woodcock, Corinne L; Lothion-Roy, Jennifer; Harris, Anna E; Nilsson, Emeli M; Ntekim, Atara; Persson, Jenny L; Robinson, Brian D; Khani, Francesca; Laursen, Kristian B; Gudas, Lorraine J; Toss, Michael S; Madhusudan, Srinivasan; Rakha, Emad; Heery, David M; Rutland, Catrin S; Mongan, Nigel P and Jeyapalan, Jennie N (2023). The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer. Frontiers in cell and developmental biology, 11, p. 1116424. Frontiers 10.3389/fcell.2023.1116424
de Brot, Simone; Lothion-Roy, Jennifer; Grau-Roma, Llorenç; White, Emily; Guscetti, Franco; Rubin, Mark A.; Mongan, Nigel P (2022). Histological and immunohistochemical investigation of canine prostate carcinoma with identification of common intraductal carcinoma component. Veterinary and comparative oncology, 20(1), pp. 38-49. Wiley 10.1111/vco.12704
Tholl, Maximilien Victor; Spring, Marc; de Brot, Simone; Casoni, Daniela; Zurbuchen, Adrian; Tanner, Hildegard; Haeberlin, Andreas (2022). Implications of wound healing on subcutaneous photovoltaic energy harvesting. IEEE transactions on biomedical engineering, 69(1), pp. 23-31. Institute of Electrical and Electronics Engineers IEEE 10.1109/TBME.2021.3086671
Ryman-Tubb, Toby; Lothion-Roy, Jennifer H; Metzler, Veronika M; Harris, Anna E; Robinson, Brian D; Rizvanov, Albert A; Jeyapalan, Jennie N; James, Victoria H; England, Gary; Rutland, Catrin S; Persson, Jenny L; Kenner, Lukas; Rubin, Mark A; Mongan, Nigel P; de Brot, Simone (2022). Comparative pathology of dog and human prostate cancer. Veterinary medicine and science, 8(1), pp. 110-120. Wiley 10.1002/vms3.642
Mohsen, Mona O; Speiser, Daniel E; Michaux, Justine; Pak, HuiSong; Stevenson, Brian J; Vogel, Monique; Inchakalody, Varghese Philipose; De Brot, Simone; Dermime, Said; Coukos, Georges; Bassani-Sternberg, Michal; Bachmann, Martin F (2022). Bedside formulation of a personalized multi-neoantigen vaccine against mammary carcinoma. Journal for immunotherapy of cancer, 10(1) BMJ Publishing Group 10.1136/jitc-2021-002927
Harris, Anna E; Metzler, Veronika M; Lothion-Roy, Jennifer; Varun, Dhruvika; Woodcock, Corinne L; Haigh, Daisy B; Endeley, Chantelle; Haque, Maria; Toss, Michael S; Alsaleem, Mansour; Persson, Jenny L; Gudas, Lorraine J; Rakha, Emad; Robinson, Brian D; Khani, Francesca; Martin, Laura M; Moyer, Jenna E; Brownlie, Juliette; Madhusudan, Srinivasan; Allegrucci, Cinzia; ... (2022). Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer. Frontiers in endocrinology, 13(1006101), p. 1006101. Frontiers Research Foundation 10.3389/fendo.2022.1006101
Simpson, Siobhan; Rizvanov, Albert A; Jeyapalan, Jennie N; De Brot, Simone; Rutland, Catrin S (2022). Canine osteosarcoma in comparative oncology: Molecular mechanisms through to treatment discovery. Frontiers in veterinary science, 9(965391), p. 965391. Frontiers Media 10.3389/fvets.2022.965391
Naim, Samara; Fernández-Marrero, Yuniel; De Brot, Simone; Bachmann, Daniel; Kaufmann, Thomas (2021). Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice. International journal of molecular sciences, 22(6) MDPI 10.3390/ijms22063281
Zhou, Bin; Tran, Thi Nhu Thao; Hoffmann, Donata; Taddeo, Adriano; Ebert, Nadine; Labroussaa, Fabien; Pohlmann, Anne; King, Jacqueline; Steiner, Silvio; Kelly, Jenna N.; Portmann, Jasmine; Halwe, Nico Joel; Ulrich, Lorenz; Trüeb, Bettina Salome; Fan, Xiaoyu; Hoffmann, Bernd; Wang, Li; Thomann, Lisa; Lin, Xudong; Stalder, Hanspeter; ... (2021). SARS-CoV-2 spike D614G change enhances replication and transmission. Nature, 592(7852), pp. 122-127. Springer Nature 10.1038/s41586-021-03361-1
Zinkhan, Simon; Ogrina, Anete; Balke, Ina; Reseviča, Gunta; Zeltins, Andris; de Brot, Simone; Lipp, Cyrill; Chang, Xinyue; Zha, Lisha; Vogel, Monique; Bachmann, Martin F.; Mohsen, Mona O. (2021). The impact of size on particle drainage dynamics and antibody response. Journal of controlled release, 331, pp. 296-308. Elsevier 10.1016/j.jconrel.2021.01.012
Rutland, Catrin S; Cockcroft, James M; Lothion-Roy, Jennifer; Harris, Anna E; Jeyapalan, Jennie N; Simpson, Siobhan; Alibhai, Aziza; Bailey, Clara; Ballard-Reisch, Alyssa C; Rizvanov, Albert A; Dunning, Mark D; De Brot, Simone; Mongan, Nigel P (2021). Immunohistochemical Characterisation of GLUT1, MMP3 and NRF2 in Osteosarcoma. Frontiers in veterinary science, 8, p. 704598. Frontiers Media 10.3389/fvets.2021.704598
Grau-Roma, Llorenç; Schock, Alex; Nofrarías, Miquel; Ali Wali, Nabil; de Fraga, Aline Padilha; Garcia-Rueda, Cristina; De Brot, Simone; Majó, Natalia (2020). Retrospective study on transmissible viral proventriculitis and chicken proventricular necrosis virus (CPNV) in the UK. Avian pathology, 49(1), pp. 99-105. Taylor & Francis 10.1080/03079457.2019.1677856
De Brot, S.; Grau-Roma, L.; Stirling-Stainsby, C.; Dettwiler, M.; Guscetti, F.; Meier, D.; Scase, T.; Robinson, B. D.; Gardner, D.; Mongan, N. P. (2019). A Fibromyxoid Stromal Response is Associated with Muscle Invasion in Canine Urothelial Carcinoma. Journal of comparative pathology, 169, pp. 35-46. Elsevier 10.1016/j.jcpa.2019.04.003
