Niggli, Ernst

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Niggli, E (2011). Ryanodine receptors: waking up from refractoriness. Cardiovascular research, 91(4), pp. 563-564. Oxford: Oxford University Press 10.1093/cvr/cvr198

Niggli, Ernst; Keller, M.; Ullrich, N.D. (2011). Alterations of ryanodine receptor (RyR) function and arrhythmogenic Ca2+ waves in cardiomyocytes. European biophysics journal - with biophysics letters, 40(Suppl.1), S70-S70. Berlin: Springer

Fanchaouy, Mohammed; Pocsai, K.; Niggli, Ernst (2010). Redox modifications of Ca2+-release events in cardiomyocytes (Unpublished). In: Mammalian Myocardium Meeting 2010. Manchester, UK.

Niggli, Ernst (2010). ROS and Ca2+ sparks in dystrophic muscle. In: 8th Swiss Meeting on Muscle Research. Magglingen, Switzerland. 28th – 30th November 2010.

Fanchaouy, M; Pocsai, K; Shirokova, N; Rüegg, U; Niggli, E (2010). Ca2+ signals in dystrophic myotubes in primary culture. In: 8th Swiss Meeting on Muscle Research. Magglingen, Switzerland. 28th – 30th November 2010.

Ullrich, N; Fischer, D; Niggli, E; Zorzato, F; Treves, S (2010). Ca2+ homeostasis of humanmyotubes carying a CAV3 mutation linked to rippling muscle disease. In: 8th Swiss Meeting on Muscle Research. Magglingen, Switzerland. 28th – 30th November 2010.

Yes

Lopez, Ruben; Janicek, Radoslav; Fernandez-Tenorio, Miguel; Courtehoux, Marianne; Matas, Lluis; Gerbaud, Pascale; Gomez, Ana M; Egger, Marcel; Niggli, Ernst (2022). Uptake-leak balance of SR Ca2+ determines arrhythmogenic potential of RyR2R420Q+/- cardiomyocytes. Journal of molecular and cellular cardiology, 170, pp. 1-14. Elsevier 10.1016/j.yjmcc.2022.05.011

Agarwal, Hitesh K.; Janicek, Radoslav; Zhao, Jun; Sambath, Karthik; Egger, Marcel; Niggli, Ernst; Ellis-Davies, Graham C. R. (2022). The yin and yang of intracellular delivery of amphipathic optical probes using n -butyl charge masking. Chemical communications, 58(17), pp. 2826-2829. Royal Society of Chemistry 10.1039/D1CC06792C

Yin, Liheng; Zahradnikova, Alexandra; Rizzetto, Riccardo; Boncompagni, Simona; Rabesahala de Meritens, Camille; Zhang, Yadan; Joanne, Pierre; Marqués-Sulé, Elena; Aguilar-Sánchez, Yuriana; Fernández-Tenorio, Miguel; Villejoubert, Olivier; Li, Linwei; Wang, Yue Yi; Mateo, Philippe; Nicolas, Valérie; Gerbaud, Pascale; Lai, F. Anthony; Perrier, Romain; Álvarez, Julio L.; Niggli, Ernst; ... (2021). Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation. Circulation research, 129(3), e35-e52. American Heart Association 10.1161/CIRCRESAHA.121.319094

Janicek, Radoslav; Agarwal, Hitesh; Gómez, Ana M.; Egger, Marcel; Ellis‐Davies, Graham C. R.; Niggli, Ernst (2021). Local recovery of cardiac calcium‐induced calcium release interrogated by ultra‐effective, two‐photon uncaging of calcium. The journal of physiology, 599(16), pp. 3841-3852. The Physiological Society 10.1113/JP281482

Potenza, Duilio Michele; Janicek, Radoslav; Fernandez Tenorio, Miguel; Niggli, Ernst (2020). Activation of endogenous protein phosphatase 1 enhances the calcium sensitivity of the ryanodine receptor type 2 in murine ventricular cardiomyocytes. The journal of physiology, 598(6), pp. 1131-1150. The Physiological Society 10.1113/JP278951

Niggli, Ernst (2020). β-adrenergic receptors in cardiac muscle: it takes two to tango. Cardiovascular research, 116(13), pp. 2033-2035. Oxford University Press 10.1093/cvr/cvaa183

Potenza, Duilio Michele; Janicek, Radoslav; Fernandez Tenorio, Miguel; Camors, Emmanuel; Ramos-Mondragón, Roberto; Valdivia, Héctor H.; Niggli, Ernst (2019). Phosphorylation of the ryanodine receptor 2 at serine 2030 is required for a complete β-adrenergic response. Journal of general physiology, 151(2), pp. 131-145. Rockefeller University Press 10.1085/jgp.201812155

Illaste, Ardo; Wullschleger, Marcel; Fernandez Tenorio, Miguel; Niggli, Ernst; Egger, Marcel (2019). Automatic Detection and Classification of Ca2+ Release Events in Line- and Frame-Scan Images. Biophysical journal, 116(3), pp. 383-394. Biophysical Society 10.1016/j.bpj.2018.12.013

Niggli, Ernst; Fernandez Tenorio, Miguel (2019). Simultaneous Recording of Subcellular Ca2+ Signals from the Cytosol and Sarco/Endoplasmic Reticulum: Compartmentalized Dye Loading, Imaging, and Analysis. In: Heizmann, Claus W. (ed.) Calcium-Binding Proteins of the EF-Hand Superfamily. Methods in Molecular Biology: Vol. 1929 (pp. 53-71). New York, NY: Humana Press 10.1007/978-1-4939-9030-6_5

Franz, Marie-Christine; Pujol Gimenez, Jonai; Montalbetti, Nicolas; Fernandez Tenorio, Miguel; DeGrado, Timothy R.; Niggli, Ernst; Romero, Michael F.; Hediger, Matthias (2018). Reassessment of the transport mechanism of the human zinc transporter SLC39A2. Biochemistry, 57(26), pp. 3976-3986. American Chemical Society 10.1021/acs.biochem.8b00511

Shirokova, Natalia; Niggli, Ernst (2018). Duchenne Muscular Dystrophy: Emerging Pathological Role for Cardiac Myopathy. Kardiologiia: vid nauky do praktyky, 4(33), pp. 27-40. 10.30702/card:sp.2018.09.033/07

Fernandez Tenorio, Miguel; Niggli, Ernst (2018). Stabilization of Ca 2+ signaling in cardiac muscle by stimulation of SERCA. Journal of molecular and cellular cardiology, 119, pp. 87-95. Elsevier 10.1016/j.yjmcc.2018.04.015

Niggli, Ernst; Shirokova, Natalia (2018). Caged Compounds: Applications in Cardiac Muscle Research. In: Kaestner, Lars; Lipp, Peter (eds.) Microscopy of the heart (pp. 75-95). Springer 10.1007/978-3-319-95304-5_4

Srimachai, Sirintorn; Devaux, Sylvie; Demougeot, Celine; Kumphune, Sarawut; Ullrich, Nina; Niggli, Ernst; Ingkaninan, Kornkanok; Kamkaew, Natakorn; Scholfield, C. Norman; Tapechum, Sompol; Chootip, Krongkarn (2017). Bacopa monnieri extract increases rat coronary flow and protects against myocardial ischemia/reperfusion injury. BMC complementary and alternative medicine, 17(1), p. 117. BioMed Central 10.1186/s12906-017-1637-z

Fernandez Tenorio, Miguel; Niggli, Ernst (2016). Real-time intra-store confocal Ca2+ imaging in isolated mouse cardiomyocytes. Cell calcium, 60(5), pp. 331-340. Elsevier 10.1016/j.ceca.2016.07.002

Plaisance, Isabelle; Perruchoud, Stéphanie; Fernandez Tenorio, Miguel; Gonzales, Christine; Ounzain, Samir; Ruchat, Patrick; Nemir, Mohamed; Niggli, Ernst; Pedrazzini, Thierry (2016). Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression. JACC. Basic to translational science, 1(6), pp. 472-493. Elsevier 10.1016/j.jacbts.2016.06.008

Agarwal, Hitesh K.; Janicek, Radoslav; Chi, San-Hui; Perry, Joseph W.; Niggli, Ernst; Ellis-Davies, Graham C. R. (2016). Calcium Uncaging with Visible Light. Journal of the American Chemical Society, 138(11), pp. 3687-3693. 10.1021/jacs.5b11606

Poláková, Eva; Illaste, Ardo; Niggli, Ernst; Sobie, Eric A. (2015). Maximal acceleration of calcium release refractoriness by β-adrenergic stimulation requires dual activation of protein kinase A and CaMKII in mouse ventricular myocytes. Journal of physiology, 593(6), pp. 495-507. Wiley-Blackwell 10.1113/jphysiol.2014.278051

Lorin, Charlotte; Vögeli, Isabelle; Niggli, Ernst (2015). Dystrophic cardiomyopathy: role of TRPV2 channels in stretch-induced cell damage. Cardiovascular research, 106(1), pp. 153-162. Oxford University Press 10.1093/cvr/cvv021

Niggli, Ernst (2015). IP 3 and Ca 2+ signals in the heart: boost them or bust them? Journal of physiology, 593(6), pp. 1385-1386. Wiley-Blackwell 10.1113/jphysiol.2014.287987

Shirokova, Natalia; Kang, Chifei; Fernandez Tenorio, Miguel; Wang, Wei; Wang, Qiongling; Wehrens, Xander H.T.; Niggli, Ernst (2014). RETRACTED: Oxidative Stress and Ca2+ Release Events in Mouse Cardiomyocytes. Biophysical journal, 107(12), pp. 2815-2827. Biophysical Society 10.1016/j.bpj.2014.10.054

Gutierrez Pineda, Daniel A.; Fernandez Tenorio, Miguel; Ogrodnik, Jakob; Niggli, Ernst (2013). NO-dependent CaMKII activation during -adrenergic stimulation of cardiac muscle. Cardiovascular research, 100(3), pp. 392-401. Oxford University Press 10.1093/cvr/cvt201

Shirokova, Natalia; Niggli, Ernst (2013). Cardiac phenotype of Duchenne Muscular Dystrophy: Insights from cellular studies. Journal of molecular and cellular cardiology, 58, pp. 217-224. Elsevier 10.1016/j.yjmcc.2012.12.009

Niggli, Ernst; Ullrich, Nina D.; Gutierrez Pineda, Daniel A.; Kyrychenko, Sergii; Poláková, Eva; Shirokova, Natalia (2013). Posttranslational modifications of cardiac ryanodine receptors: Ca2+ signaling and EC-coupling. Biochimica et biophysica acta - molecular cell research, 1833(4), pp. 866-875. Elsevier 10.1016/j.bbamcr.2012.08.016

Kyrychenko, S.; Polakova, E.; Kang, C.; Pocsai, K.; Ullrich, Nina D.; Niggli, Ernst; Shirokova, N. (2013). Hierarchical accumulation of RyR post-translational modifications drives disease progression in dystrophic cardiomyopathy. Cardiovascular research, 97(4), pp. 666-675. Oxford University Press 10.1093/cvr/cvs425

Niggli, E (2011). Measuring calcium in ‘fuzzy’ spaces. Journal of physiology, 589(11), p. 2663. Oxford: Wiley-Blackwell 10.1113/jphysiol.2011.210336

Niggli, E. (2010). Ca2+ on the move: what is better fire and forget, or fire diffuse fire? Journal of physiology, 588(9), 1391 -1392. Oxford: Wiley-Blackwell 10.1113/jphysiol.2010.190306

Ogrodnik, J.; Niggli, E. (2010). Increased Ca2+ leak and spatiotemporal coherence of Ca2+ release in cardiomyocytes during -adrenergic stimulation. Journal of physiology, 588(1), pp. 225-242. Oxford: Wiley-Blackwell 10.1113/jphysiol.2009.181800

Ogrodnik, J.; Gutierrez Pineda, Daniel Arturo; Niggli, Ernst (2010). b-Adrenergic stimulation increases SR Ca2+ leak in cardiomyocytes. Biophysical journal, 98(3), 549a-550a. Bethesda, Md.: Biophysical Society

Swift, Frederik; Tovsrud, N.; Sjaastad, I.; Sejersted, O. M.; Niggli, Ernst; Egger, Marcel (2010). Functional coupling of alpha2-isoform Na+/K+-ATPase and Ca2+ extrusion through the Na+/Ca2+ -exchanger in cardiomyocytes. Cell calcium, 48(1), pp. 54-60. Amsterdam: Elsevier 10.1016/j.ceca.2010.06.006

Ullrich, Nina; Niggli, Ernst (2010). Impaired re-synchronization of RyR2 activation during b-adrenergic stimulation in RyR2-S2808A mouse cardiomyocytes. Biophysical journal, 98(3), 549a. Bethesda, Md.: Biophysical Society

Niggli, E (2009). How to shut down Ca2+-induced Ca2+ release? Journal of physiology, 587(21), pp. 5003-5004. Oxford: Wiley-Blackwell 10.1113/jphysiol.2009.181578

Shkryl, VM; Martins, AS; Ullrich, ND; Nowycky, MC; Niggli, E; Shirokova, N (2009). Reciprocal amplification of ROS and Ca2+ signals in stressed mdx dystrophic skeletal muscle fibers. Pflügers Archiv : European journal of physiology, 458(5), pp. 915-928. Berlin: Springer 10.1007/s00424-009-0670-2

Jung, Carole; Martins, Adriano S; Niggli, Ernst; Shirokova, Natalia (2008). Dystrophic cardiomyopathy: amplification of cellular damage by Ca2+ signalling and reactive oxygen species-generating pathways. Cardiovascular research, 77(4), pp. 766-773. Oxford: Oxford University Press 10.1093/cvr/cvm089

Keller, Markus; Kao, Joseph P Y; Egger, Marcel; Niggli, Ernst (2007). Calcium waves driven by "sensitization" wave-fronts. Cardiovascular research, 74(1), pp. 39-45. Oxford: Elsevier Science 10.1016/j.cardiores.2007.02.006

Niggli, Ernst; Kléber, André; Weingart, Robert (2006). Founder of cardiac cellular electrophysiology: honouring Silvio Weidmann, 7 April 1921- 11 July 2005. Journal of physiology, 570(Pt 3), pp. 431-2. Oxford: Wiley-Blackwell 10.1113/jphysiol.2005.101550

Keller, M.; Pignier, C.; Niggli, E.; Egger, M. (2004). Mechanisms of Na+-Ca2+ Exchange Inhibition by Amphiphiles in CardiacMyocytes: Importance of Transbilayer Movement. The Journal of Membrane Biology, 198(3), pp. 159-175. Springer-Verlag 10.1007/s00232-004-0668-9

Niggli, Ernst; Lipp, Peter (1995). Subcellular features of calcium signalling in heart muscle: What do we learn? Cardiovascular research, 29(4), pp. 441-448. Elsevier Science 10.1016/S0008-6363(96)88517-8

Schulze, Dan; Kofuji, Paulo; Hadley, Robert; Kirby, Mark S; Kieval, Robert S; Doering, Andrea; Niggli, Ernst; Lederer, W J (1993). Sodium/calcium exchanger in heart muscle: molecular biology, cellular function, and its special role in excitation-contraction coupling. Cardiovascular research, 27(10), pp. 1726-1734. Oxford University Press 10.1093/cvr/27.10.1726

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