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Lam, K.-T.; Taylor, E. L.; Thompson, Andrew James; Ruepp, Marc-David; Lochner, Martin; Martinez, M. J.; Brozik, James A. (2020). Direct Measurement of Single-Molecule Ligand-Receptor Interactions. Journal of physical chemistry - B, 124(36), pp. 7791-7802. American Chemical Society 10.1021/acs.jpcb.0c05474
Loffreda, Alessia; Nizzardo, Monica; Arosio, Alessandro; Ruepp, Marc-David; Calogero, Raffaele A.; Volinia, Stefano; Galasso, Marco; Bendotti, Caterina; Ferrarese, Carlo; Lunetta, Christian; Rizzuti, Mafalda; Ronchi, Antonella; Mühlemann, Oliver; Tremolizzo, Lucio; Corti, Stefania; Barabino, Silvia M.L. (2020). miR-129-5p: A key factor and therapeutic target in amyotrophic lateral sclerosis. Progress in neurobiology, 190, p. 101803. Elsevier 10.1016/j.pneurobio.2020.101803
Bracher, Lisamaria; Ferro, Iolanda; Pulido-Quetglas, Carlos; Ruepp, Marc-David; Johnson, Rory; Polacek, Norbert (2020). Human vtRNA1-1 Levels Modulate Signaling Pathways and Regulate Apoptosis in Human Cancer Cells. Biomolecules, 10(4), p. 614. MDPI 10.3390/biom10040614
Schürch, Christian M; Rölli, Matthias A.; Forster, Stefan; Wasmer, Marie-Hélène; Brühl, Frido; Maire, Renaud S.; Di Pancrazio, Sergio; Ruepp, Marc-David; Giger, Roland; Perren, Aurel; Schmitt, Anja M.; Krebs, Philippe; Charles, Roch-Philippe; Dettmer, Matthias S. (2019). Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy. Thyroid, 29(7), pp. 979-992. Mary Ann Liebert 10.1089/thy.2018.0555
Jack, Thomas; Leuenberger, Michele; Ruepp, Marc-David; Vernekar, Sanjeev Kumar V; Thompson, Andrew James; Braga-Lagache, Sophie; Heller, Manfred; Lochner, Martin (2019). Mapping the Orthosteric Binding Site of the Human 5-HT3 Receptor Using Photo-crosslinking Antagonists. ACS chemical neuroscience, 10(1), pp. 438-450. American Chemical Society 10.1021/acschemneuro.8b00327
Loughlin, Fionna E.; Lukavsky, Peter J.; Kazeeva, Tamara; Reber, Stefan; Hock, Eva-Maria; Colombo, Martino; Von Schroetter, Christine; Pauli, Phillip; Cléry, Antoine; Mühlemann, Oliver; Polymenidou, Magdalini; Ruepp, Marc-David; Allain, Frédéric H.-T. (2019). The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity. Molecular cell, 73(3), 490-504.e6. Cell Press 10.1016/j.molcel.2018.11.012
Reber, Stefan; Mechtersheimer, Jonas Matthias; Nasif, Sofia; Benitez, Julio Aguila; Colombo, Martino; Domanski, Michal; Jutzi, Daniel; Hedlund, Eva; Ruepp, Marc-David; Matera, A. Gregory (2018). CRISPR-Trap: a clean approach for the generation of gene knockouts and gene replacements in human cells. Molecular biology of the cell, 29(2), pp. 75-83. American Society for Cell Biology 10.1091/mbc.E17-05-0288
Ruepp, Marc-David; Wei, Hao; Leuenberger, Michele; Lochner, Martin; Thompson, Andrew James (2017). The binding orientation of structurally-related ligands can differ; A cautionary note. Neuropharmacology, 119, pp. 48-61. Elsevier 10.1016/j.neuropharm.2017.01.023
Thompson, Andrew J.; Metzger, Simon; Lochner, Martin; Ruepp, Marc-David (2017). The binding orientation of epibatidine at α7 nACh receptors. Neuropharmacology, 116, pp. 421-428. Elsevier 10.1016/j.neuropharm.2017.01.008
Lochner, Martin; Jack, Thomas; Simonin, Jonathan; Leuenberger, Michele; Rüefli, Pascal; Bur-Cecilio Hechavarria, Yamileidi; Ruepp, Marc-David; Thompson, Andrew J. (August 2016). Investigation of the interaction between 5-HT3R and its modulators: progress in understanding the agonist binding site. CHIMIA, 70(7/8), MC121. Schweizerische Chemische Gesellschaft
Leuenberger, Michele; Ritler, Andreas; Aerni, Valerie; Metzger, Simon G.; Ruepp, Marc-David; Lochner, Martin (August 2016). New insights into glutamate transport in brain: Concise asymmetric synthesis of TFB-TBOA and photoaffinity probes. CHIMIA, 70(7/8), MC123. Schweizerische Chemische Gesellschaft
Reber, Stefan; Stettler, Jolanda; Filosa, G.; Colombo, Martino; Jutzi, D.; Lenzken, S. C.; Schweingruber, Christoph; Bruggmann, Rémy; Bachi, A.; Barabino, S. M.; Mühlemann, Oliver; Ruepp, Marc-David (2016). Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants. EMBO journal, 35(14), pp. 1504-1521. Nature Publishing Group 10.15252/embj.201593791
Suárez-Calvet, Marc; Neumann, Manuela; Arzberger, Thomas; Abou-Ajram, Claudia; Funk, Eva; Hartmann, Hannelore; Edbauer, Dieter; Kremmer, Elisabeth; Göbl, Christoph; Resch, Moritz; Bourgeois, Benjamin; Madl, Tobias; Reber, Stefan; Jutzi, Daniel; Ruepp, Marc-David; Mackenzie, Ian R. A.; Ansorge, Olaf; Dormann, Dorothee; Haass, Christian (2016). Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS. Acta neuropathologica, 131(4), pp. 587-604. Springer 10.1007/s00401-016-1544-2
Schweingruber, Christoph; Soffientini, Paolo; Ruepp, Marc-David; Bachi, Angela; Mühlemann, Oliver (2016). Identification of Interactions in the NMD Complex Using Proximity-Dependent Biotinylation (BioID). PLoS ONE, 11(3), e0150239. Public Library of Science 10.1371/journal.pone.0150239
Leuenberger, Michele; Jack, Thomas; Ruepp, Marc-David; Lagache, Sophie; Heller, Manfred; Mühlemann, Oliver; Thompson, Andrew J.; Lochner, Martin (15 June 2015). Synthesis of photo-crosslinking probes and their application for the site-selective chemical modification of the 5-HT3 receptor (Unpublished). In: Challenges in Chemical Biology (ISACS16). Book of Abstracts. ETH Zürich, Hönggerberg, Switzerland. 15.06.-18.06.2015.
Barden, Adam O.; Goler, Adam S.; Humphreys, Sara C.; Tabatabaei, Samaneh; Lochner, Martin; Ruepp, Marc-David; Jack, Thomas; Simonin, Jonathan; Thompson, Andrew James; Jones, Jeffrey P.; Brozik, James A. (2015). Tracking individual membrane proteins and their biochemistry: The power of direct observation. Neuropharmacology, 98, pp. 22-30. Elsevier 10.1016/j.neuropharm.2015.05.003
Jack, Thomas; Simonin, Jonathan; Ruepp, Marc-David; Thompson, Andrew James; Gertsch, Jürg; Lochner, Martin (2015). Characterizing New Fluorescent Tools for Studying 5-HT3 Receptor Pharmacology. Neuropharmacology, 90, pp. 63-73. Elsevier 10.1016/j.neuropharm.2014.11.007
Raczynska, Katarzyna Dorota; Ruepp, Marc-David; Brzek, Aleksandra; Reber, Stefan; Romeo, Valentina; Rindlisbacher, Barbara; Heller, Manfred; Szweykowska-Kulinska, Zofia; Jarmolowski, Artur; Schümperli, Daniel (2015). FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors. Nucleic acids research, 43(20), pp. 9711-9728. Oxford University Press 10.1093/nar/gkv794
Ruepp, Marc-David; Brozik, James A.; de Esch, Iwan J.P.; Farndale, Richard W.; Murrell-Lagnado, Ruth D.; Thompson, Andrew J. (2015). A fluorescent approach for identifying P2X1 ligands. Neuropharmacology, 98, pp. 13-21. Elsevier 10.1016/j.neuropharm.2015.05.016
Ruepp, Marc-David (22 October 2014). The FUS(s) about splicing (Unpublished). In: TERM meeting 2014. Paris, Frankreich. 22.10.-23.10.2014.
Lochner, Martin; Jack, Thomas; Simonin, Jonathan; Ruepp, Marc-David; Leuenberger, Michele; Hemmings, Jennifer Luise; Singhanat, Suradech; Thompson, Andrew James (2 October 2014). Studying Ion Channels and Receptors Using Synthetic Molecular Probes (Unpublished). In: 3rd Swiss-Japanese Chemical Biology Symposium. Bern, Switzerland. 02.-03.10.2014.
Lochner, Martin; Jack, Thomas; Simonin, Jonathan; Singhanat, Suradech; Leuenberger, Michele; Ruepp, Marc-David; Hemmings, Jennifer Luise; Thompson, Andrew James (20 August 2014). Synthesis of Molecular Tools for the Cellular Study of Ion Channels and Receptors (Unpublished). In: EMBO Conference Chemical Biology. Heidelberg, Germany. 20.-23.08.2014.
Jack, Thomas; Ruepp, Marc-David; Thompson, Andrew J.; Mühlemann, Oliver; Lochner, Martin (2014). Synthesis and Characterization of Photoaffinity Probes that Target the 5-HT<SUB>3</SUB> Receptor. CHIMIA, 68(4), pp. 239-242. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2014.239
Nizzardo, Monica; Simone, Chiara; Salani, Sabrina; Ruepp, Marc-David; Rizzo, Federica; Ruggieri, Margherita; Zanetta, Chiara; Brajkovic, Simona; Moulton, Hong M.; Mühlemann, Oliver; Bresolin, Nereo; Comi, Giacomo P.; Corti, Stefania (2014). Effect of Combined Systemic and Local Morpholino Treatment on the Spinal Muscular Atrophy Δ7 Mouse Model Phenotype. Clinical therapeutics, 36(3), 340-356.e5. Elsevier 10.1016/j.clinthera.2014.02.004
Ruepp, Marc-David (24 January 2014). The role of FUS in splicing regulation (Unpublished). In: Swiss RNA Workshop 2014. Bern, Schweiz. 24.01.2014.
Ruepp, Marc-David (24 January 2014). Genetic Engineering of Induced Pluripotent Stem Cells and Reprogramming to Motor Neurons to Elucidate Selective Motor Neuron Death in Amyotrophic Lateral Sclerosis (Unpublished). In: Swiss RNA Workshop 2014. Bern, Schweiz. 24.01.2014.
Ruepp, Marc-David (24 January 2014). Characterization of the role of the RNA-binding protein FUS in the DNA damage response (Unpublished). In: Swiss RNA Workshop 2014. Bern, Schweiz. 24.01.2014.
Ruepp, Marc-David (24 January 2014). Proteomic characterization of the FUS/TLS interactome (Unpublished). In: Swiss RNA Workshop 2014. Bern, Schweiz. 24.01.2014.
Ruepp, Marc-David (6 September 2013). Synthesis and testing of photoaffinity probes for the site-selectivechemical modifications of the 5-HT3 receptor (Unpublished). In: 2013 Fall Meeting EPFL Lausanne. EPFL Lausanne, CH. 06.09.2013.
Ruepp, Marc-David (12 August 2013). Synthesis and testing of photoaffinity probes for the site-selective chemical modifications of the 5-HT3 receptor (Unpublished). In: Swiss Summer School 2013 in Synthesis and Catalysis. Villars, CH. 12.-16.08.2013.
Jack, Thomas; Ruepp, Marc-David; Mühlemann, Oliver; Thompson, Andrew James; Lummis, Sarah C. R.; Lochner, Martin (August 2013). Synthesis and testing of photoaffinity probes for the site-selective chemical modification of the 5-HT3 receptor. CHIMIA, 67(7/8), p. 519. Schweizerische Chemische Gesellschaft
Simonin, Jonathan; Jack, Thomas; Ruepp, Marc-David; Hothersall, Daniel; Connolly, Christopher; Chicca, Andrea; Gertsch, Jürg; Thompson, Andrew James; Lummis, Sarah C. R.; Lochner, Martin (August 2013). Synthesis of fluorescent probes for the study of the 5-HT3 receptor: applications in imaging and fluorescence polarization. CHIMIA, 67(7/8), p. 524. Schweizerische Chemische Gesellschaft
Singhanat, Suradech; Ruepp, Marc-David; Jack, Thomas; Rougier, Jean-Sébastien; Abriel, Hugues; Mühlemann, Oliver; Lochner, Martin (August 2013). Towards the site-specific modification of the hERG K+ channel. CHIMIA, 67(7/8), p. 532. Schweizerische Chemische Gesellschaft
Ruepp, Marc-David (11 June 2013). The FUS protein is required for cell proliferation (Unpublished). In: 18th International Annual Meeting of the RNA Society. Davos, CH. 11.-15.06.2013.
Ruepp, Marc-David (11 June 2013). Combined systemic and local morpholino treatment rescues the phenotype of the SMA Delta 7 mouse model (Unpublished). In: 18th International Annual Meeting of the RNA Society. Davos, CH. 11.-15.06.2013.
Ruepp, Marc-David (11 June 2013). Characterization of the potential role for RNA-binding protein FUS in DNA damage response: A quantitative proteomic approach (Unpublished). In: 18th International Annual Meeting of the RNA Society. Davos, CH. 11.-15.06.2013.
Ruepp, Marc-David (11 June 2013). The involvement of miRNA Dysregulation in Amyotrophic Lateral Sclerosis (Unpublished). In: 18th International Annual Meeting of the RNA Society. Davos, CH. 11.-15.06.2013.
Ruepp, Marc-David (11 June 2013). FUS protein interacts with U7 snRNP and plays a role in replication-dependant histone genes expression (Unpublished). In: 18th International Annual Meeting of the RNA Society. 11.-15.06.2013.
Ruepp, Marc-David (10 June 2013). Synthesis and testing of photoaffinity probes for the site-selectivechemical modifications of the 5-HT3 receptor (Unpublished). In: CUSO Subject Day "Modern Synthetic Methods and their Application in the Context of Natural Products". Neuchâtel, CH. 10.-11.06.2013.
Lochner, Martin; Jack, Thomas; Simonin, Jonathan; Singhanat, Suradech; Hemmings, Jennifer Luise; Leuenberger, Michele; Ruepp, Marc-David; Thompson, Andrew James (9 June 2013). Synthesis of Molecular Tools for the Cellular Study of Ion Channels and Receptors (Unpublished). In: Gordon Research Conference Bioorganic Chemistry. Andover, NH, USA. 09.-14.06.2013.
Lochner, Martin; Jack, Thomas; Simonin, Jonathan; Singhanat, Suradech; Hemmings, Jennifer Luise; Leuenberger, Michele; Thompson, Andrew James; Ruepp, Marc-David (26 April 2013). Chemical Tools for the Study and Modification of Ion Channels and Receptors (Unpublished). In: BioChemLig Meeting. Bern. 26.04.2013.
Ruepp, Marc-David (25 January 2013). Characterization of the potential role for RNA-binding protein FUS/TLS in DNA damage response: A quantitative proteomic approach (Unpublished). In: Swiss RNA Workshop 2013. Bern, CH. 25.01.2013.
Ruepp, Marc-David (25 January 2013). The multifunctional FUS protein: Characterization of the biological effects of its depletion (Unpublished). In: Swiss RNA Workshop 2013. Bern, CH. 25.01.2013.
Ruepp, Marc-David (25 January 2013). Unravelling the multiple roles of FUS in RNA processing and on ALS pathogenesis (Unpublished). In: Swiss RNA Workshop 2013. Bern, CH. 25.01.2013.
Ruepp, Marc-David (25 January 2013). Unravelling the impact of microRNA on Amyotrophic Lateral Sclerosis (ALS) pathogenesis (Unpublished). In: Swiss RNA Workshop 2013. Bern, CH. 25.01.2013.
Ruepp, Marc-David (11 January 2013). Synthesis and testing of photoaffinity probes for the site-selective chemical modifications of the 5-HT3 receptor (Unpublished). In: 11th Swiss Snow Symposium 2013. Saas-Fee, CH. 11.-13.01.2013.
Metze, Stefanie; Herzog, Veronika A.; Ruepp, Marc-David; Mühlemann, Oliver (2013). Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways. RNA - a publication of the RNA Society, 19(10), pp. 1432-1448. Woodbury, N.Y.: Cold Spring Harbor Laboratory Press 10.1261/rna.038893.113
Vivarelli, Silvia; Lenzken, Silvia C.; Ruepp, Marc-David; Ranzini, Francesco; Maffioletti, Andrea; Alvarez, Reinaldo; Mühlemann, Oliver; Barabino, Silvia M. L.; Buratti, Emanuele (2013). Paraquat Modulates Alternative Pre-mRNA Splicing by Modifying the Intracellular Distribution of SRPK2. PLoS ONE, 8(4), e61980. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0061980
Ruepp, Marc-David; Schweingruber, Christoph; Kleinschmidt, Nicole; Schümperli, Daniel (2011). Interactions of CstF-64, CstF-77, and symplekin: Implications on localisation and function. Molecular biology of the cell, 22(1), pp. 91-104. Bethesda, Md.: American Society for Cell Biology 10.1091/mbc.E10-06-0543
Ruepp, Marc-David; Schümperli, Daniel; Barabino, Silvia M.L. (2011). mRNA 3' end processing and more - multiple functions of mammalian cleavage factor I-68. RNA - a publication of the RNA Society, 2(1), pp. 79-91. Woodbury, N.Y.: Cold Spring Harbor Laboratory Press 10.1002/wrna.35
Ruepp, Marc-David; Schweingruber, Christoph; Kleinschmidt, Nicole; Schümperli, Daniel (2010). Interactions of symplekin, CstF-64, and CstF-77. Implications for localisation, stability and function. In: The Fifteenth Annual Meeting of the RNA Society Seattle, Washington USA, June 22-26, 2010 (p. 1). RNA Society
Ruepp, Marc-David; Vivarelli, Silvia; Pillai, Ramesh S.; Kleinschmidt, Nicole; Azzouz, Teldja N.; Barabino, Silvia M.L.; Schümperli, Daniel (2010). The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 30-end processing of animal histone mRNAs. Nucleic acids research, 38(21), pp. 7637-7650. London: Oxford University Press 10.1093/nar/gkq613
Meyer, Kathrin; Marquis, Julien; Trüb, Judith; Nlend Nlend, Rachel; Verp, Sonia; Ruepp, Marc-David; Imboden, Hans; Barde, Isabelle; Trono, Didier; Schümperli, Daniel (2009). Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation. Human molecular genetics, 18(3), pp. 546-555. Oxford: Oxford University Press 10.1093/hmg/ddn382
Ruepp, Marc-David; Aringhieri, Chiara; Vivarelli, Silvia; Cardinale, Stefano; Paro, Simona; Schümperli, Daniel; Barabino, Silvia M.L. (2009). Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export. Molecular biology of the cell, 20(24), pp. 5211-23. Bethesda, Md.: American Society for Cell Biology 10.1091/mbc.E09-05-0389
