Zens, Philipp Immanuel

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2024

Karatkevich, Darya; Losmanová, Tereza; Zens, Philipp; Deng, Haibin; Dubey, Christelle; Zhang, Tuo; Casty, Corsin; Gao, Yanyun; Neppl, Christina; Berezowska, Sabina; Wang, Wenxiang; Peng, Ren-Wang; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas (2024). Chemotherapy increases CDA expression and sensitizes malignant pleural mesothelioma cells to capecitabine treatment. Scientific Reports, 14(18206) Nature Publishing Group 10.1038/s41598-024-69347-x

Maillard, Marie; Neppl, Christina; Zens, Philipp; Anex, Julie; Peters, Solange; Krueger, Thorsten; Berezowska, Sabina (2024). Multicenter study on tumor budding in lung squamous cell carcinoma: comparison between biopsy and resection with interobserver variability assessment. (In Press). Modern pathology, 37(10), p. 100571. Elsevier 10.1016/j.modpat.2024.100571

2023

Wang, Jun; Sun, Na; Kunzke, Thomas; Shen, Jian; Zens, Philipp; Prade, Verena M; Feuchtinger, Annette; Berezowska, Sabina; Walch, Axel (2023). Spatial metabolomics identifies distinct tumor-specific and stroma-specific subtypes in patients with lung squamous cell carcinoma. NPJ precision oncology, 7(1), p. 114. Springer Nature 10.1038/s41698-023-00434-4

Shen, Jian; Sun, Na; Wang, Jun; Zens, Philipp; Kunzke, Thomas; Buck, Achim; Prade, Verena M; Wang, Qian; Feuchtinger, Annette; Hu, Ronggui; Berezowska, Sabina; Walch, Axel (2023). Patterns of Carbon-Bound Exogenous Compounds Impact Disease Pathophysiology in Lung Cancer Subtypes in Different Ways. ACS nano, 17(17), pp. 16396-16411. American Chemical Society 10.1021/acsnano.2c11161

König, D; Savic Prince, S; Hayoz, S; Zens, P; Berezowska, S; Jochum, W; Stauffer, E; Braunersreuther, V; Trachsel, B; Thierstein, S; Mark, M; Schmid, S; Curioni-Fontecedro, A; Addeo, A; Opitz, I; Guckenberger, M; Früh, M; Betticher, D C; Ris, H-B; Stupp, R; ... (2023). Neoadjuvant treatment does not influence PD-L1 expression in stage III non-small-cell lung cancer: a retrospective analysis of tumor samples from the trials SAKK 16/96, 16/00, 16/01, and 16/14. ESMO open, 8(4), p. 101595. BMJ 10.1016/j.esmoop.2023.101595

Barrera, Cristian; Corredor, Germán; Viswanathan, Vidya Sankar; Ding, Ruiwen; Toro, Paula; Fu, Pingfu; Buzzy, Christina; Lu, Cheng; Velu, Priya; Zens, Philipp; Berezowska, Sabina; Belete, Merzu; Balli, David; Chang, Han; Baxi, Vipul; Syrigos, Konstantinos; Rimm, David L; Velcheti, Vamsidhar; Schalper, Kurt; Romero, Eduardo; ... (2023). Deep computational image analysis of immune cell niches reveals treatment-specific outcome associations in lung cancer. NPJ precision oncology, 7(1), p. 52. Springer Nature 10.1038/s41698-023-00403-x

Frei, Ana Leni; Khan, Amjad; Zens, Philipp; Lugli, Alessandro; Zlobec, Inti; Fischer, Andreas (28 April 2023). GammaFocus: An image augmentation method to focus model attention for classification. In: Medical Imaging with Deep Learning 2023.

Frei, Ana Leni; Khan, Amjad; Studer, Linda; Zens, Philipp; Lugli, Alessandro; Fischer, Andreas; Zlobec, Inti (28 April 2023). Local and global feature aggregation for accurate epithelial cell classification using graph attention mechanisms in histopathology images. In: Medical Imaging with deep Learning 2023.

Kashani, Elham; Schnidrig, Désirée; Hashemi Gheinani, Ali; Ninck, Martina Selina; Zens, Philipp; Maragkou, Theoni; Baumgartner, Ulrich; Schucht, Philippe; Rätsch, Gunnar; Rubin, Mark A; Berezowska, Sabina; Ng, Charlotte K Y; Vassella, Erik (2023). Integrated longitudinal analysis of adult grade 4 diffuse gliomas with long-term relapse interval revealed upregulation of TGF-β signaling in recurrent tumors. Neuro-Oncology, 25(4), pp. 662-673. Oxford University Press 10.1093/neuonc/noac220

2022

Zens, Philipp; Bello, Corina Manuela; Scherz, Amina; von Gunten, Michael; Ochsenbein, Adrian; Schmid, Ralph A; Berezowska, Sabina (2022). The effect of neoadjuvant therapy on PD-L1 expression and CD8+lymphocyte density in non-small cell lung cancer. Modern pathology, 35(12), pp. 1848-1859. Springer Nature 10.1038/s41379-022-01139-y

Kündig, Alexandra; Zens, Philipp; Fung, Christian; Scherz, Amina; Cerciello, Ferdinando; Herrmann, Evelyn; Ermis, Ekin; Schmid, Ralph A; Vassella, Erik; Berezowska, Sabina (2022). Programmed Death-Ligand 1 Expression in Lung Cancer and Paired Brain Metastases-a Single-Center Study in 190 Patients. JTO clinical and research reports, 3(11), p. 100413. 10.1016/j.jtocrr.2022.100413

Ding, Ruiwen; Prasanna, Prateek; Corredor, Germán; Barrera, Cristian; Zens, Philipp; Lu, Cheng; Velu, Priya; Leo, Patrick; Beig, Niha; Li, Haojia; Toro, Paula; Berezowska, Sabina; Baxi, Vipul; Balli, David; Belete, Merzu; Rimm, David L; Velcheti, Vamsidhar; Schalper, Kurt; Madabhushi, Anant (2022). Image analysis reveals molecularly distinct patterns of TILs in NSCLC associated with treatment outcome. NPJ precision oncology, 6(1), p. 33. Springer Nature 10.1038/s41698-022-00277-5

Shen, Jian; Sun, Na; Zens, Philipp; Kunzke, Thomas; Buck, Achim; Prade, Verena M; Wang, Jun; Wang, Qian; Hu, Ronggui; Feuchtinger, Annette; Berezowska, Sabina Anna; Walch, Axel (2022). Spatial metabolomics for evaluating response to neoadjuvant therapy in non-small cell lung cancer patients. Cancer communications, 42(6), pp. 517-535. Wiley 10.1002/cac2.12310

Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209

2021

Vassella, Erik; Kashani, Elham; Zens, Philipp; Kündig, Alexandra; Fung, Christian; Scherz, Amina; Herrmann, Evelyn; Ermis, Ekin; Schmid, Ralph A.; Berezowska, Sabina (2021). Mutational profiles of primary pulmonary adenocarcinoma and paired brain metastases disclose the importance of KRAS mutations. European journal of cancer, 159, pp. 227-236. Elsevier 10.1016/j.ejca.2021.10.006

Losmanová, Tereza; Zens, Philipp; Scherz, Amina; Schmid, Ralph; Tschan, Mario P.; Berezowska, Sabina Anna (2021). Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Advanced Non-Small Cell Lung Cancer after Neoadjuvant Therapy. Cells, 10(10) MDPI 10.3390/cells10102731

Zens, Philipp; Bello, Corina; Scherz, Amina; Koenigsdorf, Julia; Pöllinger, Alexander; Schmid, Ralph A.; Ochsenbein, Adrian; Neppl, Christina; Langer, Rupert; Berezowska, Sabina Anna (2021). A prognostic score for non-small cell lung cancer resected after neoadjuvant therapy in comparison with the tumor-node-metastases classification and major pathological response. Modern pathology, 34(7), pp. 1333-1344. Springer Nature 10.1038/s41379-021-00777-y

Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2

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