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van der Spoel, Evie; van Vliet, Nicolien A; Poortvliet, Rosalinde K E; Du Puy, Robert S; den Elzen, Wendy P J; Quinn, Terence J; Stott, David J; Sattar, Naveed; Kearney, Patricia M; Blum, Manuel R; Alwan, Heba; Rodondi, Nicolas; Collet, Tinh-Hai; Westendorp, Rudi G J; Ballieux, Bart E; Jukema, J Wouter; Dekkers, Olaf M; Gussekloo, Jacobijn; Mooijaart, Simon P and van Heemst, Diana (2024). Incidence and determinants of spontaneous normalization of subclinical hypothyroidism in older adults. The journal of clinical endocrinology and metabolism, 109(3), e1167-e1174. Oxford University Press 10.1210/clinem/dgad623
Baretella, Oliver; Alwan, Heba; Feller, Martin; Aubert, Carole; Del Giovane, Cinzia; Papazoglou, Dimitrios; Christiaens, Antoine; Meinders, Arend-Jan; Byrne, Stephen; Kearney, Patricia M; O'Mahony, Denis; Knol, Wilma; Boland, Benoît; Gencer, Baris; Aujesky, Drahomir; Rodondi, Nicolas (2023). Overtreatment and associated risk factors among multimorbid older patients with diabetes. Journal of the American Geriatrics Society, 71(9), pp. 2893-2901. Wiley 10.1111/jgs.18465
Netzer, Seraina; Chocano-Bedoya, Patricia; Feller, Martin; Janett-Pellegri, Camilla; Wildisen, Lea; Büchi, Annina E; Moutzouri, Elisavet; Rodriguez, Elena Gonzalez; Collet, Tinh-Hai; Poortvliet, Rosalinde K E; Mc Carthy, Vera J C; Aeberli, Daniel; Aujesky, Drahomir; Westendorp, Rudi; Quinn, Terence J; Gussekloo, Jacobijn; Kearney, Patricia M; Mooijaart, Simon; Bauer, Douglas C and Rodondi, Nicolas (2023). The effect of thyroid hormone therapy on muscle function, strength and mass in older adults with subclinical hypothyroidism-an ancillary study within two randomized placebo controlled trials. Age and ageing, 52(1), afag326. Oxford University Press 10.1093/ageing/afac326
Lyko, Christina; Blum, Manuel R; Abolhassani, Nazanin; Stuber, Mirah J; Del Giovane, Cinzia; Feller, Martin; Moutzouri, Elisavet; Oberle, Jolanda; Jungo, Katharina T; Collet, Tinh-Hai; den Elzen, Wendy P J; Poortvliet, Rosalinde K E; Du Puy, Robert S; Dekkers, Olaf M; Trompet, Stella; Jukema, J Wouter; Aujesky, Drahomir; Quinn, Terry; Westendorp, Rudi; Kearney, Patricia M; ... (2022). Thyroid antibodies and levothyroxine effects in subclinical hypothyroidism: A pooled analysis of two randomized controlled trials. Journal of internal medicine, 292(6), pp. 892-903. Wiley 10.1111/joim.13544
Büchi, Annina Elisabeth; Feller, Martin; Netzer, Seraina; Blum, Manuel R; Rodriguez, Elena Gonzalez; Collet, Tinh-Hai; Del Giovane, Cinzia; van Heemst, Diana; Quinn, Terry; Kearney, Patricia M; Westendorp, Rudi G J; Gussekloo, Jacobijn; Mooijaart, Simon; Hans, Didier; Bauer, Douglas C; Rodondi, Nicolas; Aeberli, Daniel (2022). Bone geometry in older adults with subclinical hypothyroidism upon levothyroxine therapy: A nested study within a randomized placebo controlled trial. Bone, 161, p. 116404. Elsevier 10.1016/j.bone.2022.116404
Du Puy, Robert S; Poortvliet, Rosalinde K E; Mooijaart, Simon P; Stott, David J; Quinn, Terry; Sattar, Naveed; Westendorp, Rudi G J; Kearney, Patricia M; McCarthy, Vera J C; Byrne, Stephen; Rodondi, Nicolas; Baretella, Oliver; Collet, Tinh-Hai; van Heemst, Diana; Dekkers, Olaf M; Jukema, J Wouter; Smit, Johannes W A; Gussekloo, Jacobijn; den Elzen, Wendy P J (2022). No effect of levothyroxine on hemoglobin in older adults with subclinical hypothyroidism: pooled results from two RCTs. Journal of clinical endocrinology and metabolism, 107(6), e2339-e2347. Endocrine Society 10.1210/clinem/dgac106
Buttgereit, Thomas; Palmowski, Andriko; Forsat, Noah; Boers, Maarten; Witham, Miles D; Rodondi, Nicolas; Moutzouri, Elisavet; Navidad, Antonio Jesus Quesada; Van't Hof, Arnoud W J; van der Worp, Bart; Coll-Planas, Laura; Voshaar, Marieke; de Wit, Maarten; da Silva, José; Stegemann, Sven; Bijlsma, Johannes W; Koeller, Marcus; Mooijaart, Simon; Kearney, Patricia M and Buttgereit, Frank (2021). Barriers and potential solutions in the recruitment and retention of older patients in clinical trials-lessons learned from six large multicentre randomized controlled trials. Age and ageing, 50(6), pp. 1988-1996. Oxford University Press 10.1093/ageing/afab147
Zijlstra, Laurien E; Jukema, J Wouter; Westendorp, Rudi G J; Du Puy, Robert S; Poortvliet, Rosalinde K E; Kearney, Patricia M; O'Keeffe, Linda; Dekkers, Olaf M; Blum, Manuel R.; Rodondi, Nicolas; Collet, Tinh-Hai; Quinn, Terence J; Sattar, Naveed; Stott, David J; Trompet, Stella; den Elzen, Wendy P J; Gussekloo, Jacobijn; Mooijaart, Simon P (2021). Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials. Frontiers in endocrinology, 12, p. 674841. Frontiers Research Foundation 10.3389/fendo.2021.674841
Stuber, Mirah J.; Moutzouri, Elisavet; Feller, Martin; Del Giovane, Cinzia; Bauer, Douglas C; Blum, Manuel R.; Collet, Tinh-Hai; Gussekloo, Jacobijn; Mooijaart, Simon P; McCarthy, Vera J C; Aujesky, Drahomir; Westendorp, Rudi; Stott, David J; Glynn, Nancy W; Kearney, Patricia M; Rodondi, Nicolas (2020). Effect of Thyroid Hormone Therapy on Fatigability in Older Adults With Subclinical Hypothyroidism: A Nested Study Within a Randomized Placebo-Controlled Trial. Journals of gerontology. Series A - biological sciences and medical sciences, 75(9), e89-e94. Oxford University Press 10.1093/gerona/glaa123
de Montmollin, Maria Karolina; Feller, Martin; Beglinger, Shanthi; McConnachie, Alex; Aujesky, Drahomir; Collet, Tinh-Hai; Ford, Ian; Gussekloo, Jacobijn; Kearney, Patricia M; McCarthy, Vera J C; Mooijaart, Simon; Poortvliet, Rosalinde K E; Quinn, Terence; Stott, David J; Watt, Torquil; Westendorp, Rudi; Rodondi, Nicolas; Bauer, Douglas C (2020). L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial. Annals of internal medicine, 172(11), pp. 709-716. American College of Physicians 10.7326/M19-3193
Gonzalez Rodriguez, Elena; Stuber, Mirah; Del Giovane, Cinzia; Feller, Martin; Collet, Tinh-Hai; Löwe, Axel L; Blum, Manuel R; van Vliet, Nicolien A; van Heemst, Diana; Kearney, Patricia M; Gussekloo, Jacobijn; Mooijaart, Simon; Westendorp, Rudi G J; Stott, David J; Aeberli, Daniel; Bauer, Douglas C; Hans, Didier; Rodondi, Nicolas (2020). Skeletal Effects of Levothyroxine for Subclinical Hypothyroidism in Older Adults: A TRUST Randomized Trial Nested Study. Journal of clinical endocrinology and metabolism, 105(1), dgz058. Endocrine Society 10.1210/clinem/dgz058
Mooijaart, Simon P; Du Puy, Robert S; Stott, David J; Kearney, Patricia M; Rodondi, Nicolas; Westendorp, Rudi G J; den Elzen, Wendy P J; Postmus, Iris; Poortvliet, Rosalinde K E; van Heemst, Diana; van Munster, Barbara C; Peeters, Robin P; Ford, Ian; Kean, Sharon; Messow, Claudia-Martina; Blum, Manuel R; Collet, Tinh-Hai; Watt, Torquil; Dekkers, Olaf M; Jukema, J Wouter; ... (2019). Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism. JAMA - the journal of the American Medical Association, 322(20), pp. 1977-86. American Medical Association 10.1001/jama.2019.17274
Adam, Luise; Moutzouri, Elisavet; Baumgartner, Christine; Loewe, Axel Lennart; Feller, Martin; M'Rabet Bensalah, Khadija; Schwab, Nathalie; Hossmann, Stefanie; Schneider, Claudio; Jegerlehner, Sabrina; Floriani, Carmen; Limacher, Andreas; Jungo, Katharina Tabea; Huibers, Corlina Johanna Alida; Streit, Sven; Schwenkglenks, Matthias; Spruit, Marco; van Dorland, Hendrika Anette; Donzé, Jacques; Kearney, Patricia M; ... (2019). Rationale and design of OPtimising thERapy to prevent Avoidable hospital admissions in Multimorbid older people (OPERAM): a cluster randomised controlled trial [protocol]. BMJ open, 9(6), e026769. BMJ Publishing Group 10.1136/bmjopen-2018-026769
Meuwese, Christiaan L; van Diepen, Merel; Cappola, Anne R; Sarnak, Mark J; Shlipak, Michael G; Bauer, Douglas C; Fried, Linda P; Iacoviello, Massimo; Vaes, Bert; Degryse, Jean; Khaw, Kay-Tee; Luben, Robert N; Åsvold, Bjørn O; Bjøro, Trine; Vatten, Lars J; de Craen, Anton J M; Trompet, Stella; Iervasi, Giorgio; Molinaro, Sabrina; Ceresini, Graziano; ... (2019). Low thyroid function is not associated with an accelerated deterioration in renal function. Nephrology, dialysis, transplantation, 34(4), pp. 650-659. Oxford University Press 10.1093/ndt/gfy071
Feller, Martin; Snel, Marieke; Moutzouri, Elisavet; Bauer, Douglas C; de Montmollin, Maria; Aujesky, Drahomir; Ford, Ian; Gussekloo, Jacobijn; Kearney, Patricia M; Mooijaart, Simon; Quinn, Terry; Stott, David; Westendorp, Rudi; Rodondi, Nicolas; Dekkers, Olaf M (2018). Association of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis. JAMA - the journal of the American Medical Association, 320(13), pp. 1349-1359. American Medical Association 10.1001/jama.2018.13770
O Riordan, David; Aubert, Carole Elodie; Walsh, Kieran A; van Dorland, Anette; Rodondi, Nicolas; Du Puy, Robert S; Poortvliet, Rosalinde K E; Gussekloo, Jacobijn; Sinnott, Carol; Byrne, Stephen; Galvin, Rose; Jukema, J Wouter; Mooijaart, Simon P; Baumgartner, Christine; McCarthy, Vera; Walsh, Elaine K; Collet, Tinh-Hai; Dekkers, Olaf M; Blum, Manuel R and Kearney, Patricia M (2018). Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study. BMJ open, 8(3), e019003. BMJ Publishing Group 10.1136/bmjopen-2017-019003
Aubert, Carole E; Floriani, Carmen; Bauer, Douglas C; Da Costa, Bruno; Segna, Daniel; Blum, Manuel R; Collet, Tinh-Hai; Fink, Howard A; Cappola, Anne R; Syrogiannouli, Lamprini; Peeters, Robin P; Åsvold, Bjørn O; den Elzen, Wendy Pj; Luben, Robert N; Bremner, Alexandra P; Gogakos, Apostolos; Eastell, Richard; Kearney, Patricia M; Hoff, Mari; Le Blanc, Erin; ... (2017). Thyroid function tests in the reference range and fracture: individual participant analysis of prospective cohorts. Journal of clinical endocrinology and metabolism, 102(8), pp. 2719-2728. Endocrine Society 10.1210/jc.2017-00294
Stott, David J; Rodondi, Nicolas; Kearney, Patricia M; Ford, Ian; Westendorp, Rudi G J; Mooijaart, Simon P; Sattar, Naveed; Aubert, Carole E; Aujesky, Drahomir; Bauer, Douglas C; Baumgartner, Christine; Blum, Manuel R; Browne, John P; Byrne, Stephen; Collet, Tinh-Hai; Dekkers, Olaf M; den Elzen, Wendy P J; Du Puy, Robert S; Ellis, Graham; Feller, Martin; ... (2017). Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism. New England journal of medicine NEJM, 376(26), pp. 2534-2544. Massachusetts Medical Society MMS 10.1056/NEJMoa1603825
Stott, David J; Gussekloo, Jacobijn; Kearney, Patricia M; Rodondi, Nicolas; Westendorp, Rudi G J; Mooijaart, Simon; Kean, Sharon; Quinn, Terence J; Sattar, Naveed; Hendry, Kirsty; Du Puy, Robert; Den Elzen, Wendy P J; Poortvliet, Rosalinde K E; Smit, Jan W A; Jukema, J Wouter; Dekkers, Olaf M; Blum, Manuel; Collet, Tinh-Hai; McCarthy, Vera; Hurley, Caroline; ... (2017). Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism - a randomised placebo controlled Trial (TRUST). BMC Endocrine Disorders, 17(1), p. 6. BioMed Central 10.1186/s12902-017-0156-8
Boef, Anna G C; le Cessie, Saskia; Dekkers, Olaf M; Frey, Peter; Kearney, Patricia M; Kerse, Ngaire; Mallen, Christian D; McCarthy, Vera J C; Mooijaart, Simon P; Muth, Christiane; Rodondi, Nicolas; Rosemann, Thomas; Russell, Audrey; Schers, Henk; Virgini, Vanessa; de Waal, Margot W M; Warner, Alex; Gussekloo, Jacobijn; den Elzen, Wendy P J (2016). Physician's Prescribing Preference as an Instrumental Variable: Exploring Assumptions Using Survey Data. Epidemiology, 27(2), pp. 276-283. Wolters Kluwer Health, Lippincott Williams & Wilkins 10.1097/EDE.0000000000000425
Blum, Manuel; Wijsman, Liselotte W; Virgini, Vanessa S; Bauer, Douglas C; den Elzen, Wendy P J; Jukema, J Wouter; Buckley, Brendan M; de Craen, Anton J M; Kearney, Patricia M; Stott, David J; Gussekloo, Jacobjin; Westendorp, Rudi G J; Mooijaart, Simon P; Rodondi, Nicolas (2016). Subclinical Thyroid Dysfunction and Depressive Symptoms among Elderly: A Prospective Cohort Study. Neuroendocrinology, 103(3-4), pp. 291-299. Karger 10.1159/000437387
Åsvold, Bjørn O; Vatten, Lars J; Bjøro, Trine; Bauer, Douglas C; Bremner, Alexandra; Cappola, Anne R; Ceresini, Graziano; den Elzen, Wendy P J; Ferrucci, Luigi; Franco, Oscar H; Franklyn, Jayne A; Gussekloo, Jacobijn; Iervasi, Giorgio; Imaizumi, Misa; Kearney, Patricia M; Khaw, Kay-Tee; Maciel, Rui M B; Newman, Anne B; Peeters, Robin P; Psaty, Bruce M; ... (2015). Thyroid function within the normal range and risk of coronary heart disease: an individual participant data analysis of 14 cohorts. JAMA Internal Medicine, 175(6), pp. 1037-1047. American Medical Association 10.1001/jamainternmed.2015.0930
Blum, Manuel R; Bauer, Douglas C; Collet, Tinh-Hai; Fink, Howard A; Cappola, Anne R; da Costa, Bruno R; Wirth, Christina D; Peeters, Robin P; Åsvold, Bjørn O; den Elzen, Wendy P J; Luben, Robert N; Imaizumi, Misa; Bremner, Alexandra P; Gogakos, Apostolos; Eastell, Richard; Kearney, Patricia M; Strotmeyer, Elsa S; Wallace, Erin R; Hoff, Mari; Ceresini, Graziano; ... (2015). Subclinical thyroid dysfunction and fracture risk: a meta-analysis. JAMA - the journal of the American Medical Association, 313(20), pp. 2055-2065. American Medical Association 10.1001/jama.2015.5161
Virgini, Vanessa Sophie; Wijsman, Liselotte W; Rodondi, Nicolas; Bauer, Douglas C; Kearney, Patricia M; Gussekloo, Jacobijn; den Elzen, Wendy P J; Jukema, J Wouter; Westendorp, Rudi G J; Ford, Ian; Stott, David J; Mooijaart, Simon P (2014). Subclinical thyroid dysfunction and functional capacity among elderly. Thyroid, 24(2), pp. 208-214. Mary Ann Liebert 10.1089/thy.2013.0071
