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Eggimann, Matthias; Akhoundova, Dilara; Nilius, Henning; Hoffmann, Michèle; Hayoz, Michael; Aebi, Yolanda; Largiadèr, Carlo R; Daskalakis, Michael; Bacher, Ulrike; Pabst, Thomas (2024). Safety and Efficacy of High-Dose Chemotherapy with TreoMel 200 vs. TreoMel 140 in Acute Myeloid Leukemia Patients Undergoing Autologous Stem Cell Transplantation. Cancers, 16(10) MDPI AG 10.3390/cancers16101887
Morandi, Sophia C; Herzog, Elio L; Munk, Marion; Kreuzer, Marco; Largiadèr, Carlo R; Wolf, Sebastian; Zinkernagel, Martin; Zysset-Burri, Denise C (2024). The gut microbiome and HLA-B27-associated anterior uveitis: a case-control study. Journal of neuroinflammation, 21(120) BioMed Central 10.1186/s12974-024-03109-4
Neyer, Peter J; Kaboré, Bérenger; Nakas, Christos T; Diallo, Salou; Tinto, Halidou; Post, Annelies; van der Ven, Andre J; Huber, Andreas R; Largiadèr, Carlo R; Hammerer-Lercher, Angelika (2024). Increased erythroferrone levels in malarial anaemia. British journal of haematology, 204(5), pp. 2066-2070. Wiley 10.1111/bjh.19309
Zhang, Ting; Ambrodji, Alisa; Huang, Huixing; Bouchonville, Kelly J; Etheridge, Amy S; Schmidt, Remington E; Bembenek, Brianna M; Temesgen, Zoey B; Wang, Zhiquan; Innocenti, Federico; Stroka, Deborah; Diasio, Robert B; Largiadèr, Carlo R; Offer, Steven M (2024). Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD). eLife, 13 eLife Sciences Publications 10.7554/eLife.94075
Le Teuff, Gwénaël; Cozic, Nathalie; Boyer, Jean-Christophe; Boige, Valérie; Diasio, Robert B; Taieb, Julien; Meulendijks, Didier; Palles, Claire; Schwab, Matthias; Deenen, Maarten; Largiadèr, Carlo R; Marinaki, Anthony; Jennings, Barbara A; Wettergren, Yvonne; Di Paolo, Antonello; Gross, Eva; Budai, Barna; Ackland, Stephen P; van Kuilenburg, André B P; McLeod, Howard L; ... (2024). Dihydropyrimidine dehydrogenase gene variants for predicting grade 4-5 fluoropyrimidine-induced toxicity: FUSAFE individual patient data meta-analysis. British journal of cancer, 130(5), pp. 808-818. Springer Nature 10.1038/s41416-023-02517-2
Neyer, Peter J; Kaboré, Bérenger; Nakas, Christos T.; Hartmann, Britta; Post, Annelies; Diallo, Salou; Tinto, Halidou; Hammerer-Lercher, Angelika; Largiadèr, Carlo R; van der Ven, Andre J; Huber, Andreas R (2023). Exploring the host factors affecting asymptomatic Plasmodium falciparum infection: insights from a rural Burkina Faso study. Malaria journal, 22(1), p. 252. BioMed Central 10.1186/s12936-023-04686-0
Kueng, Nicholas; Sidler, Daniel; Banz, Vanessa; Largiadèr, Carlo R; Ng, Charlotte K Y; Amstutz, Ursula (2023). Investigation of Different Library Preparation and Tissue of Origin Deconvolution Methods for Urine and Plasma cfDNA Methylome Analysis. Diagnostics, 13(15) MDPI 10.3390/diagnostics13152505
Gillich, Cédric; Akhoundova, Dilara; Hayoz, Michael; Aebi, Yolanda; Largiadèr, Carlo R; Seipel, Katja; Daskalakis, Michael; Bacher, Vera; Pabst, Thomas (2023). Efficacy and Safety of High-Dose Chemotherapy with Treosulfan and Melphalan in Multiple Myeloma. Cancers, 15(10) MDPI AG 10.3390/cancers15102699
Kueng, Nicholas; Arcioni, Séverine; Sandberg, Fanny; Kuhn, Christian; Banz, Vanessa; Largiadèr, Carlo R; Sidler, Daniel; Amstutz, Ursula (2023). Comparison of methods for donor-derived cell-free DNA quantification in plasma and urine from solid organ transplant recipients. Frontiers in genetics, 14(1089830), p. 1089830. Frontiers Media SA 10.3389/fgene.2023.1089830
Schmulenson, Eduard; Bovet, Cédric; Theurillat, Regula; Decosterd, Laurent Arthur; Largiadèr, Carlo R; Prost, Jean-Christophe; Csajka, Chantal; Bärtschi, Daniela; Guckenberger, Matthias; von Moos, Roger; Bastian, Sara; Joerger, Markus; Jaehde, Ulrich (2022). Population pharmacokinetic analyses of regorafenib and capecitabine in patients with locally advanced rectal cancer (SAKK 41/16 RECAP). British journal of clinical pharmacology, 88(12), pp. 5336-5347. Wiley-Blackwell 10.1111/bcp.15461
Horn, Michael P; Jonsdottir, Hulda R; Brigger, Daniel; Damonti, Lauro; Suter-Riniker, Franziska; Endrich, Olga; Froehlich, Tanja K; Fiedler, Martin; Largiadèr, Carlo R; Marschall, Jonas; Weber, Benjamin; Eggel, Alexander; Nagler, Michael (2022). Serological testing for SARS-CoV-2 antibodies in clinical practice: a comparative diagnostic accuracy study. Allergy, 77(7), pp. 2090-2103. Wiley 10.1111/all.15206
Begré, Ursina B M; Jörger, Markus; Aebi, Stefan; Amstutz, Ursula; Largiadèr, Carlo R (2022). Clinical Implementation of DPYD Pharmacogenetic Testing to Prevent Early-Onset Fluoropyrimidine-Related Toxicity in Cancer Patients in Switzerland. Frontiers in Pharmacology, 13, p. 885259. Frontiers 10.3389/fphar.2022.885259
Gurevich, Ekaterina; Hayoz, Michael; Aebi, Yolanda; Largiadèr, Carlo R; Mansouri Taleghani, Behrouz; Bacher, Ulrike; Pabst, Thomas (2022). Comparison of Melphalan Combined with Treosulfan or Busulfan as High-Dose Chemotherapy before Autologous Stem Cell Transplantation in AML. Cancers, 14(4) MDPI AG 10.3390/cancers14041024
Dietmann, Anelia; Wenzel, Elena; van der Meer, Julia; Ringli, Maya; Warncke, Jan D; Edwards, Ellen; Schmidt, Markus H; Bernasconi, Corrado A; Nirkko, Arto; Strub, Mathias; Miano, Silvia; Manconi, Mauro; Acker, Jens; von Manitius, Sigrid; Baumann, Christian R; Valko, Philip O; Yilmaz, Bahtiyar; Brunner, Andreas-David; Tzovara, Athina; Zhang, Zhongxing; ... (2021). The Swiss Primary Hypersomnolence and Narcolepsy Cohort study (SPHYNCS): Study protocol for a prospective, multicentre cohort observational study. Journal of sleep research, 30(5), e13296. Wiley 10.1111/jsr.13296
Tarasco, Erika; Bütikofer, Lukas; Friedman, Kenneth D; George, James N; Hrachovinova, Ingrid V; Knöbl, Paul; Matsumoto, Masanori; von Krogh, Anne Sophie; Aebi-Huber, Isabella; Cermakova, Zuzana; Górska-Kosicka, Magdalena; Jalowiec, Katarzyna A; Largiadèr, Carlo R; Prohaszka, Zoltan; Sinkovits, György; Windyga, Jerzy; Lämmle, Bernhard; Kremer Hovinga, Johanna A (2021). Annual Incidence and Severity of Acute Episodes in Hereditary Thrombotic Thrombocytopenic Purpura. Blood, 137(25), pp. 3563-3575. American Society of Hematology 10.1182/blood.2020009801
Sistonen, Johanna; Smith, Chingying; Fu, Yung-Kang; Largiadèr, Carlo R (2012). A new DPYD genotyping assay for improving the safety of 5-fluorouracil therapy. Clinica chimica acta, 414, pp. 109-111. Amsterdam: Elsevier 10.1016/j.cca.2012.08.015
Amstutz, Ursula; Andrey-Zürcher, Gisela; Suciu, Dominic; Jaggi, Rolf; Häberle, Johannes; Largiadèr, Carlo R (2011). Sequence capture and next-generation resequencing of multiple tagged nucleic acid samples for mutation screening of urea cycle disorders. Clinical chemistry, 57(1), pp. 102-11. Washington, D.C.: American Association for Clinical Chemistry 10.1373/clinchem.2010.150706
Amstutz, Ursula; Froehlich, Tanja K; Largiadèr, Carlo R (2011). Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity. Pharmacogenomics, 12(9), pp. 1321-36. London: Future Medicine 10.2217/PGS.11.72
Kuhn-Nentwig, Lucia; Largiadèr, Carlo R; Streitberger, Kathrin; Chandru, Sathyan; Baumann, Tommy; Kämpfer, Urs; Schaller, Johann; Schürch, Stefan; Nentwig, Wolfgang (2011). Purification, cDNA structure and biological significance of a single insulin-like growth factor-binding domain protein (SIBD-1) identified in the hemocytes of the spider Cupiennius salei. Insect biochemistry and molecular biology, 41(11), pp. 891-901. Amsterdam: Elsevier 10.1016/j.ibmb.2011.08.003
van Kuilenburg, André B P; Largiadèr, Carlo R (2011). SNPs and Haplotypes in DPYD and Outcome of Capecitabine-Letter. Clinical cancer research, 17(17), 5837; author reply 5835-6. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-11-1258
Bittner, David; Cossins, Andrew R; Segner, Helmut; Excoffier, Laurent; Largiadèr, Carlo R (2011). Identification of candidate genes and physiological pathways involved in gonad deformation in whitefish (Coregonus spp.) from Lake Thun, Switzerland. International journal of environmental research and public health, 8(7), pp. 2706-33. Basel: MDPI 10.3390/ijerph8072706
Baumann, Tommy; Kuhn-Nentwig, Lucia; Largiadèr, Carlo R; Nentwig, Wolfgang (2010). Expression of defensins in non-infected araneomorph spiders. Cellular and molecular life sciences, 67(15), pp. 2643-51. Basel: SP Birkhäuser Verlag Basel 10.1007/s00018-010-0354-2
Amstutz, Ursula; Farese, Simone; Aebi, Stefan; Largiadèr, Carlo R (2008). Hypermethylation of the DPYD promoter region is not a major predictor of severe toxicity in 5-fluorouracil based chemotherapy. Clinical cancer research, 27(1), p. 54. Philadelphia, Pa.: American Association for Cancer Research 10.1186/1756-9966-27-54
Engel, Katharina; Nuoffer, Jean-Marc; Mühlhausen, Chris; Klaus, Vera; Largiadèr, Carlo R; Tsiakas, Konstantinos; Santer, René; Wermuth, Bendicht; Häberle, Johannes (2008). Analysis of mRNA transcripts improves the success rate of molecular genetic testing in OTC deficiency. Molecular genetics and metabolism, 94(3), pp. 292-7. Amsterdam: Elsevier 10.1016/j.ymgme.2008.03.009
Giger, Thomas; Excoffier, Laurent; Amstutz, Ursula; Day, Philip J R; Champigneulle, Alexis; Hansen, Michael M; Kelso, Janet; Largiadèr, Carlo R (2008). Population transcriptomics of life-history variation in the genus Salmo. Molecular Ecology, 17(13), pp. 3095-3108. Oxford: Wiley-Blackwell 10.1111/j.1365-294X.2008.03820.x
Neuenschwander, Samuel; Largiadèr, Carlo R; Ray, Nicolas; Currat, Mathias; Vonlanthen, Pascal; Excoffier, Laurent (2008). Colonization history of the Swiss Rhine basin by the bullhead (Cottus gobio): inference under a Bayesian spatially explicit framework. Molecular Ecology, 17(3), pp. 757-772. Oxford: Wiley-Blackwell 10.1111/j.1365-294X.2007.03621.x
Giger, Thomas; Excoffier, Laurent; Day, Philip J R; Champigneulle, Alexis; Hansen, Michael M; Powell, Richard; Largiadèr, Carlo R (2006). Life history shapes gene expression in salmonids. Current Biology, 16(8), R281-R282. Cambridge, Mass.: Cell Press 10.1016/j.cub.2006.03.053
Bakker, Theo C M; Zbinden, Marc; Frommen, Joachim G; Weiss, Alexander; Largiadèr, Carlo R (2006). Slow fertilization of stickleback eggs: the result of sexual conflict? BMC ecology, 6(1), p. 7. London: BioMed Central 10.1186/1472-6785-6-7
