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Sivapalan, Praleene; Kaas-Hansen, Benjamin Skov; Meyhoff, Tine Sylvest; Hjortrup, Peter Buhl; Kjær, Maj-Brit N; Laake, Jon Henrik; Cronhjort, Maria; Jakob, Stephan M; Cecconi, Maurizio; Nalos, Marek; Ostermann, Marlies; Malbrain, Manu L N G; Møller, Morten Hylander; Perner, Anders; Granholm, Anders (2024). Effects of IV fluid restriction according to site-specific intensity of standard fluid treatment-protocol. Acta anaesthesiologica Scandinavica, 68(7), pp. 975-982. Wiley 10.1111/aas.14423
Borthwick, Mark; Granholm, Anders; Marker, Søren; Krag, Mette; Lange, Theis; Wise, Matt P; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Schefold, Joerg C; Wetterslev, Jørn; Perner, Anders; Møller, Morten Hylander (2024). Associations between enteral nutrition and outcomes in the SUP-ICU trial: Results of exploratory post hoc analyses. (In Press). Acta anaesthesiologica Scandinavica Wiley 10.1111/aas.14471
Meyhoff, Tine Sylvest; Granholm, Anders; Hjortrup, Peter Buhl; Sivapalan, Praleene; Lange, Theis; Laake, Jon Henrik; Cronhjort, Maria; Jakob, Stephan M; Cecconi, Maurizio; Nalos, Marek; Ostermann, Marlies; Malbrain, Manu L N G; Møller, Morten Hylander; Perner, Anders (2024). Albumin use in patients with septic shock-Post-hoc analyses of an international randomised fluid trial. Acta anaesthesiologica Scandinavica, 68(3), pp. 372-384. Wiley 10.1111/aas.14359
Sivapalan, Praleene; Meyhoff, Tine Sylvest; Hjortrup, Peter Buhl; Lange, Theis; Kaas-Hansen, Benjamin Skov; Kjaer, Maj-Brit N; Laake, Jon Henrik; Cronhjort, Maria; Jakob, Stephan M; Cecconi, Maurizio; Nalos, Marek; Ostermann, Marlies; Malbrain, Manu L N G; Møller, Morten Hylander; Perner, Anders; Granholm, Anders (2024). Restrictive versus standard IV fluid therapy in adult ICU patients with septic shock-Bayesian analyses of the CLASSIC trial. Acta anaesthesiologica Scandinavica, 68(2), pp. 236-246. Wiley 10.1111/aas.14345
Wichmann, Sine; Lange, Theis; Perner, Anders; Gluud, Christian; Itenov, Theis S; Berthelsen, Rasmus E; Nebrich, Lars; Wiis, Jørgen; Brøchner, Anne C; Nielsen, Louise G; Behzadi, Meike T; Damgaard, Kjeld; Andreasen, Anne S; Strand, Kristian; Järvisalo, Mikko; Strøm, Thomas; Eschen, Camilla T; Vang, Marianne L; Hildebrandt, Thomas; Andersen, Finn H; ... (2024). Furosemide versus placebo for fluid overload in intensive care patients-The randomised GODIF trial second version: Statistical analysis plan. Acta anaesthesiologica Scandinavica, 68(1), pp. 130-136. Wiley 10.1111/aas.14320
Aslam, Tayyba N; Klitgaard, Thomas L; Ahlstedt, Christian A O; Andersen, Finn H; Chew, Michelle S; Collet, Marie O; Cronhjort, Maria; Estrup, Stine; Fossum, Ole K; Frisvold, Shirin K; Gillmann, Hans-Joerg; Granholm, Anders; Gundem, Trine M; Hauss, Kristin; Hollenberg, Jacob; Huanca Condori, Maria E; Hästbacka, Johanna; Johnstad, Bror A; Keus, Eric; Kjaer, Maj-Brit N; ... (2023). A survey of preferences for respiratory support in the intensive care unit for patients with acute hypoxaemic respiratory failure. Acta anaesthesiologica Scandinavica, 67(10), pp. 1383-1394. Wiley-Blackwell 10.1111/aas.14317
Meyhoff, Tine Sylvest; Granholm, Anders; Hjortrup, Peter Buhl; Sivapalan, Praleene; Lange, Theis; Laake, Jon Henrik; Cronhjort, Maria; Jakob, Stephan M; Cecconi, Maurizio; Nalos, Marek; Ostermann, Marlies; Malbrain, Manu L N G; Møller, Morten Hylander; Perner, Anders (2023). Albumin administration in septic shock-Protocol for post-hoc analyses of data from a multicentre RCT. Acta anaesthesiologica Scandinavica, 67(8), pp. 1128-1136. Wiley-Blackwell 10.1111/aas.14280
Kjær, Maj-Brit Nørregaard; Meyhoff, Tine Sylvest; Sivapalan, Praleene; Granholm, Anders; Hjortrup, Peter Buhl; Madsen, Martin Bruun; Møller, Morten Hylander; Egerod, Ingrid; Wetterslev, Jørn; Lange, Theis; Cronhjort, Maria; Laake, Jon Henrik; Jakob, Stephan M; Nalos, Marek; Ostermann, Marlies; Gould, Doug; Cecconi, Maurizio; Malbrain, Manu L N G; Ahlstedt, Christian; Kiel, Louise Bendix; ... (2023). Long-term effects of restriction of intravenous fluid in adult ICU patients with septic shock. Intensive care medicine, 49(7), pp. 820-830. Springer 10.1007/s00134-023-07114-8
Borthwick, Mark; Granholm, Anders; Marker, Søren; Krag, Mette; Lange, Theis; Wise, Matt P; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Schefold, Joerg C; Wetterslev, Jørn; Perner, Anders; Møller, Morten Hylander (2023). Associations between enteral nutrition and outcomes in the SUP-ICU trial: Protocol for exploratory post-hoc analyses. Acta anaesthesiologica Scandinavica, 67(4), pp. 481-486. Wiley-Blackwell 10.1111/aas.14194
Granholm, Anders; Munch, Marie Warrer; Andersen-Ranberg, Nina; Myatra, Sheila Nainan; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Venkatesh, Balasubramanian; Jha, Vivekanand; Rubenson, Rebecka Wahlin; Jakob, Stephan M; Cioccari, Luca; Møller, Morten Hylander; Perner, Anders (2023). Heterogenous treatment effects of dexamethasone 12 mg vs. 6 mg in patients with COVID-19 and severe hypoxaemia - post hoc exploratory analyses of the COVID STEROID 2 trial. Acta anaesthesiologica Scandinavica, 67(2), pp. 195-205. Wiley 10.1111/aas.14167
Meyhoff, Tine S; Hjortrup, Peter B; Wetterslev, Jørn; Sivapalan, Praleene; Laake, Jon H; Cronhjort, Maria; Jakob, Stephan M; Cecconi, Maurizio; Nalos, Marek; Ostermann, Marlies; Malbrain, Manu; Pettilä, Ville; Møller, Morten H; Kjær, Maj-Brit N; Lange, Theis; Overgaard-Steensen, Christian; Brand, Björn A; Winther-Olesen, Marie; White, Jonathan O; Quist, Lars; ... (2022). Restriction of Intravenous Fluid in ICU Patients with Septic Shock. The New England journal of medicine, 386(26), pp. 2459-2470. Massachusetts Medical Society 10.1056/NEJMoa2202707
Granholm, Anders; Kjær, Maj-Brit Nørregaard; Munch, Marie Warrer; Myatra, Sheila Nainan; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Cronhjort, Maria; Wahlin, Rebecka Rubenson; Jakob, Stephan M; Cioccari, Luca; Vesterlund, Gitte Kingo; Meyhoff, Tine Sylvest; Helleberg, Marie; Møller, Morten Hylander; Benfield, Thomas; Venkatesh, Balasubramanian; Hammond, Naomi E; Micallef, Sharon; Bassi, Abhinav; John, Oommen; Jha, Vivekanand; ... (2022). Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia. Intensive care medicine, 48(5), pp. 580-589. Springer 10.1007/s00134-022-06677-2
Granholm, Anders; Munch, Marie Warrer; Myatra, Sheila Nainan; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Cronhjort, Maria; Wahlin, Rebecka Rubenson; Jakob, Stephan M; Cioccari, Luca; Kjær, Maj-Brit Nørregaard; Vesterlund, Gitte Kingo; Meyhoff, Tine Sylvest; Helleberg, Marie; Møller, Morten Hylander; Benfield, Thomas; Venkatesh, Balasubramanian; Hammond, Naomi E; Micallef, Sharon; Bassi, Abhinav; John, Oommen; Jha, Vivekanand; ... (2022). Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial. Intensive care medicine, 48(1), pp. 45-55. Springer 10.1007/s00134-021-06573-1
Munch, Marie W; Myatra, Sheila N; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Saseedharan, Sanjith; Benfield, Thomas; Wahlin, Rebecka R; Rasmussen, Bodil S; Andreasen, Anne Sofie; Poulsen, Lone M; Cioccari, Luca; Khan, Mohd S; Kapadia, Farhad; Divatia, Jigeeshu V; Brøchner, Anne C; Bestle, Morten H; Helleberg, Marie; Michelsen, Jens; Padmanaban, Ajay; Bose, Neeta; Møller, Anders; ... (2021). Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial. JAMA : the journal of the American Medical Association, 326(18), pp. 1807-1817. American Medical Association 10.1001/jama.2021.18295
Munch, Marie Warrer; Meyhoff, Tine Sylvest; Helleberg, Marie; Kjaer, Maj-Brit Nørregaard; Granholm, Anders; Hjortsø, Carl Johan Steensen; Jensen, Thomas Steen; Møller, Morten Hylander; Hjortrup, Peter Buhl; Wetterslev, Mik; Vesterlund, Gitte Kingo; Russell, Lene; Jørgensen, Vibeke Lind; Kristiansen, Klaus Tjelle; Benfield, Thomas; Ulrik, Charlotte Suppli; Andreasen, Anne Sofie; Bestle, Morten Heiberg; Poulsen, Lone Musaeus; Hildebrandt, Thomas; ... (2021). Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia: The COVID STEROID randomised, placebo-controlled trial. Acta anaesthesiologica Scandinavica, 65(10), pp. 1421-1430. Wiley 10.1111/aas.13941
Munch, Marie Warrer; Granholm, Anders; Myatra, Sheila Nainan; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Cronhjort, Maria; Wahlin, Rebecka Rubenson; Jakob, Stephan M; Cioccari, Luca; Kjaer, Maj-Brit Nørregaard; Vesterlund, Gitte Kingo; Meyhoff, Tine Sylvest; Helleberg, Marie; Møller, Morten Hylander; Benfield, Thomas; Venkatesh, Balasubramanian; Hammond, Naomi; Micallef, Sharon; Bassi, Abhinav; John, Oommen; Jha, Vivekanand; ... (2021). Higher vs. Lower Doses of Dexamethasone in Patients with COVID-19 and Severe Hypoxia (COVID STEROID 2) trial: protocol and statistical analysis plan. Acta anaesthesiologica Scandinavica, 65(6), pp. 834-845. Wiley-Blackwell 10.1111/aas.13795
Granholm, Anders; Munch, Marie Warrer; Myatra, Sheila Nainan; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Cronhjort, Maria; Wahlin, Rebecka Rubenson; Jakob, Stephan M; Cioccari, Luca; Kjaer, Maj-Brit Nørregaard; Vesterlund, Gitte Kingo; Meyhoff, Tine Sylvest; Helleberg, Marie; Møller, Morten Hylander; Benfield, Thomas; Venkatesh, Balasubramanian; Hammond, Naomi; Micallef, Sharon; Bassi, Abhinav; John, Oommen; Jha, Vivekanand; ... (2021). Higher vs Lower Doses of Dexamethasone in Patients with COVID-19 and Severe Hypoxia (COVID STEROID 2) trial: Protocol for a secondary Bayesian analysis. Acta anaesthesiologica Scandinavica, 65(5), pp. 702-710. Wiley-Blackwell 10.1111/aas.13793
Schjørring, Olav L; Klitgaard, Thomas L; Perner, Anders; Wetterslev, Jørn; Lange, Theis; Siegemund, Martin; Bäcklund, Minna; Keus, Frederik; Laake, Jon H; Morgan, Matthew; Thormar, Katrin M; Rosborg, Søren A; Bisgaard, Jannie; Erntgaard, Annette E S; Lynnerup, Anne-Sofie H; Pedersen, Rasmus L; Crescioli, Elena; Gielstrup, Theis C; Behzadi, Meike T; Poulsen, Lone M; ... (2021). Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure. The New England journal of medicine, 384(14), pp. 1301-1311. Massachusetts Medical Society 10.1056/NEJMoa2032510
Vesterlund, Gitte K; Ostermann, Marlies; Myatra, Sheila N; Arabi, Yaseen M; Sadat, Musharaf; Zampieri, Fernando G; Cronhjort, Maria; Schefold, Joerg C.; Stöhr, Frederik; Buanes, Eirik A; Bäcklund, Minna; Thormar, Katrin M; Perner, Anders (2021). Preferences for measurement and supplementation of magnesium, phosphate and zinc in ICUs: The international WhyTrace survey. Acta anaesthesiologica Scandinavica, 65(3), pp. 390-396. Wiley-Blackwell 10.1111/aas.13738
Petersen, Marie Warrer; Meyhoff, Tine Sylvest; Helleberg, Marie; Kjær, Maj-Brit Nørregaard; Granholm, Anders; Hjortsø, Carl Johan Steensen; Jensen, Thomas Steen; Møller, Morten Hylander; Hjortrup, Peter Buhl; Wetterslev, Mik; Vesterlund, Gitte Kingo; Russell, Lene; Jørgensen, Vibeke Lind; Tjelle, Klaus; Benfield, Thomas; Ulrik, Charlotte Suppli; Andreasen, Anne Sofie; Mohr, Thomas; Bestle, Morten H; Poulsen, Lone Musaeus; ... (2020). Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia (COVID STEROID) trial-Protocol and statistical analysis plan. Acta anaesthesiologica Scandinavica, 64(9), pp. 1365-1375. Wiley-Blackwell 10.1111/aas.13673
Kjaer, Maj-Brit Nørregaard; Meyhoff, Tine Sylvest; Madsen, Martin Bruun; Hjortrup, Peter Buhl; Møller, Morten Hylander; Egerod, Ingrid; Wetterslev, Jørn; Lange, Theis; Cronhjort, Maria; Laake, Jon Henrik; Jakob, Stephan M.; Nalos, Marek; Pettilä, Ville; van der Horst, Iwan C C; Ostermann, Marlies; Mouncey, Paul; Cecconi, Maurizio; Ferrer, Ricard; L N G Malbrain, Manu; Ahlstedt, Christian; ... (2020). Long-term patient-important outcomes after septic shock: a protocol for 1-year follow-up of the CLASSIC-trial. Acta anaesthesiologica Scandinavica, 64(3), pp. 410-416. Wiley-Blackwell 10.1111/aas.13519
Granholm, Anders; Lange, Theis; Anthon, Carl Thomas; Marker, Søren; Krag, Mette; Meyhoff, Tine Sylvest; Wise, Matt P; Borthwick, Mark; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Schefold, Jörg C.; Wetterslev, Jørn; Perner, Anders; Møller, Morten Hylander (2019). Time to onset of gastrointestinal bleeding in the SUP-ICU trial: a preplanned substudy. Acta anaesthesiologica Scandinavica, 63(10), pp. 1346-1356. Wiley-Blackwell 10.1111/aas.13459
Marker, Søren; Krag, Mette; Perner, Anders; Wetterslev, Jørn; Lange, Theis; Wise, Matt P; Borthwick, Mark; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Schefold, Jörg Christian; Rasmussen, Bodil S; Elkmann, Thomas; Bestle, Morten; Arenkiel, Bjørn; Laake, Jon H; Kamper, Maj K; Lång, Maarit; Pawlowicz-Dworzanska, Malgorzata B; Karlsson, Sari; ... (2019). Pantoprazole in ICU patients at risk for gastrointestinal bleeding-1-year mortality in the SUP-ICU trial. Acta anaesthesiologica Scandinavica, 63(9), pp. 1184-1190. Wiley-Blackwell 10.1111/aas.13436
Meyhoff, Tine Sylvest; Hjortrup, Peter Buhl; Møller, Morten Hylander; Wetterslev, Jørn; Lange, Theis; Kjaer, Maj-Brit Nørregaard; Jonsson, Andreas Bender; Hjortsø, Carl Johan Steensen; Cronhjort, Maria; Laake, Jon Henrik; Jakob, Stephan M.; Nalos, Marek; Pettilä, Ville; van der Horst, Iwan; Ostermann, Marlies; Mouncey, Paul; Rowan, Kathy; Cecconi, Maurizio; Ferrer, Ricard; Malbrain, Manu L N G; ... (2019). Conservative vs liberal fluid therapy in septic shock (CLASSIC) trial-Protocol and statistical analysis plan. Acta anaesthesiologica Scandinavica, 63(9), pp. 1262-1271. Wiley-Blackwell 10.1111/aas.13434
Schefold, Jörg Christian; Krag, Mette; Marker, Søren; Perner, Anders; Wetterslev, Jørn; Wise, Matt P.; Borthwick, Mark; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Lange, Theis; Møller, Morten Hylander (2019). Outcomes of Prophylactic Pantoprazole in Adult Intensive Care Unit Patients Receiving Dialysis: Results of a Randomized Trial. American journal of nephrology, 50(4), pp. 312-319. Karger 10.1159/000502732
Marker, Søren; Perner, Anders; Wetterslev, Jørn; Krag, Mette; Lange, Theis; Wise, Matt P; Borthwick, Mark; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Schefold, Jörg Christian; Møller, Morten Hylander (2019). Pantoprazole prophylaxis in ICU patients with high severity of disease: a post hoc analysis of the placebo-controlled SUP-ICU trial. Intensive care medicine, 45(5), pp. 609-618. Springer-Verlag 10.1007/s00134-019-05589-y
Krag, Mette; Marker, Søren; Perner, Anders; Wetterslev, Jørn; Wise, Matt P; Schefold, Joerg C.; Keus, Frederik; Guttormsen, Anne B; Bendel, Stepani; Borthwick, Mark; Lange, Theis; Rasmussen, Bodil S; Siegemund, Martin; Bundgaard, Helle; Elkmann, Thomas; Jensen, Jacob V; Nielsen, Rune D; Liboriussen, Lisbeth; Bestle, Morten H; Elkjær, Jeanie M; ... (2018). Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU. The New England journal of medicine, 379(23), pp. 2199-2208. Massachusetts Medical Society 10.1056/NEJMoa1714919
Collet, Marie O; Caballero, Jesús; Sonneville, Romain; Bozza, Fernando A; Nydahl, Peter; Schandl, Anna; Wøien, Hilden; Citerio, Giuseppe; van den Boogaard, Mark; Hästbacka, Johanna; Hänggi, Matthias; Colpaert, Kirsten; Rose, Louise; Barbateskovic, Marija; Lange, Theis; Jensen, Aksel; Krog, Martin B; Egerod, Ingrid; Nibro, Helle L; Wetterslev, Jørn; ... (2018). Prevalence and risk factors related to haloperidol use for delirium in adult intensive care patients: the multinational AID-ICU inception cohort study. Intensive care medicine, 44(7), pp. 1081-1089. Springer 10.1007/s00134-018-5204-y
Perner, Anders; Cecconi, Maurizio; Cronhjort, Maria; Darmon, Michael; Jakob, Stephan; Pettilä, Ville; van der Horst, Iwan C C (2018). Expert statement for the management of hypovolemia in sepsis. Intensive care medicine, 44(6), pp. 791-798. Springer-Verlag 10.1007/s00134-018-5177-x
Schefold, Joerg C.; Perner, Anders; Lange, Theis; Wetterslev, Jørn; Wise, Matt P; Borthwick, Mark; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Marker, Søren; Krag, Mette; Møller, Morten Hylander (2018). Effects of stress ulcer prophylaxis in adult ICU patients receiving renal replacement therapy (Sup-Icu RENal, SIREN): Study protocol for a pre-planned observational study. Trials, 19(1), p. 26. BioMed Central 10.1186/s13063-017-2408-3
Varis, Elina; Pettilä, Ville Yrjö Olavi; Poukkanen, Meri; Jakob, Stephan; Karlsson, Sari; Perner, Anders; Takala, Jukka; Wilkman, Erika (2017). Evolution of Blood Lactate and 90-Day Mortality in Septic Shock. A Post Hoc Analysis of the Finnaki Study. Shock, 47(5), pp. 574-581. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000772
Pettilä, Ville Yrjö Olavi; Hjortrup, Peter Buhl; Jakob, Stephan; Wilkman, Erika; Perner, Anders; Takala, Jukka (2016). Control groups in recent septic shock trials: a systematic review. Intensive care medicine, 42(12), pp. 1912-1921. Springer 10.1007/s00134-016-4444-y
Pettilä, Ville Yrjö Olavi; Merz, Tobias Michael; Wilkman, Erika; Perner, Anders; Karlsson, Sari; Lange, Theis; Hästbacka, Johanna; Hjortrup, Peter Buhl; Kuitunen, Anne; Jakob, Stephan; Takala, Jukka (2016). Targeted tissue perfusion versus macrocirculation-guided standard care in patients with septic shock (TARTARE-2S): study protocol and statistical analysis plan for a randomized controlled trial. Trials, 17(384), p. 384. BioMed Central 10.1186/s13063-016-1515-x
Krag, Mette; Perner, Anders; Wetterslev, Jørn; Wise, Matt P.; Borthwick, Mark; Bendel, Stepani; Pelosi, Paolo; Keus, Frederik; Guttormsen, Anne Berit; Schefold, Joerg C.; Møller, Morten Hylander (2016). Stress ulcer prophylaxis with a proton pump inhibitor versus placebo in critically ill patients (SUP-ICU trial): study protocol for a randomised controlled trial. Trials, 17(205), p. 205. BioMed Central 10.1186/s13063-016-1331-3
