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Georges, Nadine DF; Oberli, Beatrice; Rau, Tilman; Galván, José; Nagtegaal, Iris D; Dawson, Heather; Blank, Annika; Kohler, Andreas; Lugli, Alessandro; Zlobec, Inti (2021). Tumour budding and CD8+ T-cells: "attackers" and "defenders" in rectal cancer with and without neoadjuvant chemoradiotherapy. Histopathology, 78(7), pp. 1009-1018. Wiley 10.1111/his.14319
Rottenburger, Christof; Nicolas, Guillaume P; McDougall, Lisa; Kaul, Felix; Cachovan, Michal; Vija, A Hans; Schibli, Roger; Geistlich, Susanne; Schumann, Anne; Rau, Tilman; Glatz, Kathrin; Behe, Martin; Christ, Emanuel R; Wild, Damian (2020). Cholecystokinin-2 Receptor Agonist 177Lu-PP-F11N for Radionuclide Therapy of Medullary Thyroid Carcinoma - Results of the Lumed Phase 0a Study. Journal of nuclear medicine, 61(4), pp. 520-526. Society of Nuclear Medicine 10.2967/jnumed.119.233031
León-Castillo, Alicia; Britton, Heidi; McConechy, Melissa K; McAlpine, Jessica N; Nout, Remi; Kommoss, Stefan; Brucker, Sara Y; Carlson, Joseph W; Epstein, Elisabeth; Rau, Tilman; Bosse, Tjalling; Church, David N; Gilks, C Blake (2020). Interpretation of somatic POLE mutations in endometrial carcinoma. Journal of pathology, 250(3), pp. 323-335. Wiley 10.1002/path.5372
León-Castillo, Alicia; Gilvazquez, Ester; Nout, Remi; Smit, Vincent T H B M; McAlpine, Jessica N; McConechy, Melissa; Kommoss, Stefan; Brucker, Sara Y; Carlson, Joseph W; Epstein, Elisabeth; Rau, Tilman; Soslow, Robert A; Ganesan, Raji; Matias-Guiu, Xavier; Oliva, Esther; Harrison, Beth T; Church, David N; Gilks, C Blake; Bosse, Tjalling (2020). Clinicopathological and molecular characterisation of "multiple classifier" endometrial carcinomas. Journal of pathology, 250(3), pp. 312-322. Wiley 10.1002/path.5373
Alday-Parejo, Begoña; Richard, François; Wörthmüller, Janine; Rau, Tilman; Galván, José A.; Desmedt, Christine; Santamaria-Martinez, Albert; Rüegg, Curzio (2020). MAGI1, a New Potential Tumor Suppressor Gene in Estrogen Receptor Positive Breast Cancer. Cancers, 12(1) MDPI AG 10.3390/cancers12010223
Varga, Zsuzsanna; Li, Qiyu; Jochum, Wolfram; Perriard, Ulrike; Rau, Tilman; Tille, Jean-Christoph; Hawle, Hanne; Klingbiel, Dirk; Thuerlimann, Beat; Ruhstaller, Thomas (2019). Ki-67 assessment in early breast cancer: SAKK28/12 validation study on the IBCSG VIII and IBCSG IX cohort. Scientific reports, 9(1), p. 13534. Springer Nature 10.1038/s41598-019-49638-4
Böhm, Julian; Muenzner, Julienne Kathrin; Caliskan, Aylin; Ndreshkjana, Benardina; Erlenbach-Wünsch, Katharina; Merkel, Susanne; Croner, Roland; Rau, Tilman; Geppert, Carol Immanuel; Hartmann, Arndt; Roehe, Adriana Vial; Schneider-Stock, Regine (2019). Loss of enhancer of zeste homologue 2 (EZH2) at tumor invasion front is correlated with higher aggressiveness in colorectal cancer cells. Journal of cancer research and clinical oncology, 145(9), pp. 2227-2240. 10.1007/s00432-019-02977-1
Papadia, Andrea; Morosi, Chiara; Wang, Junjie; Gasparri, Marialuigia; Rau, Tilman; Ghezzi, Fabio; Mueller, Michael D. (2019). SLN mapping in early-stage cervical cancer as a minimal-invasive triaging tool for multimodal treatment. European journal of surgical oncology EJSO, 45(4), pp. 679-683. Elsevier 10.1016/j.ejso.2019.01.184
Trippel, Mafalda; Slotta-Huspenina, Julia; Becker, Karen; Rau, Tilman; Paepke, Stefan; Maurer-Marti, Franziska; Langer, Rupert (2018). Macroscopic Evaluation of the Trimmed Frozen Block Is a Helpful Tool for Intraoperative Assessment of Resection Margins of Breast Cancer Specimens. International journal of surgical pathology, 26(8), pp. 693-700. Sage 10.1177/1066896918780346
Graule, Janina; Uth-Gottardi, Kristin; Fischer, Elia Luca; Centeno Ramos, Irene; Galván Hernández, José Alberto; Eichmann, Micha David; Rau, Tilman; Langer, Rupert; Dawson, Heather; Nitsche, Ulrich; Traeger, Peter; Berger, Martin Dave; Schnüriger, Beat; Hädrich, Marion; Studer, Peter; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario; Zlobec, Inti (2018). CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway. Clinical epigenetics, 10(1), p. 120. Springer 10.1186/s13148-018-0548-2
Eichhorn, Philip; Andraschke, Udo; Dross, Fritz; Geppert, Carol I; Hartmann, Arndt; Rau, Tilman (2018). Restoration of an academic historical gross pathology collection-refreshed impact on current medical teaching? Virchows Archiv, 473(2), pp. 219-228. Springer 10.1007/s00428-018-2369-2
Papadia, Andrea; Gasparri, Maria Luisa; Radan, Anda-Petronela; Stämpfli, Chantal A L; Rau, Tilman; Mueller, Michael D (2018). Retrospective validation of the laparoscopic ICG SLN mapping in patients with grade 3 endometrial cancer. Journal of cancer research and clinical oncology, 144(7), pp. 1385-1393. Springer 10.1007/s00432-018-2648-y
Tegtmeyer, Nicole; Wessler, Silja; Necchi, Vittorio; Rohde, Manfred; Harrer, Aileen; Rau, Tilman; Asche, Carmen Isabell; Boehm, Manja; Loessner, Holger; Figueiredo, Ceu; Naumann, Michael; Palmisano, Ralf; Solcia, Enrico; Ricci, Vittorio; Backert, Steffen (2017). Helicobacter pylori Employs a Unique Basolateral Type IV Secretion Mechanism for CagA Delivery. Cell host & microbe, 22(4), 552-560.e5. Cell Press 10.1016/j.chom.2017.09.005
Trippel, Mafalda; Imboden, Sara; Papadia, Andrea; Mueller, Michael; Mertineit, Nando; Härmä, Kirsi Hannele; Nicolae, Alina; Vassella, Erik; Rau, Tilman (2017). Intestinal differentiated mucinous adenocarcinoma of the endometrium with sporadic MSI high status: a case report. Diagnostic pathology, 12(1), p. 39. BioMed Central 10.1186/s13000-017-0629-0
Rau, Tilman; Dawson, Heather; Hartmann, A; Rüschoff, J (2017). [Hereditary colorectal cancer : An update on genetics and entities in terms of differential diagnosis]. Der Pathologe, 38(3), pp. 156-163. Springer 10.1007/s00292-017-0294-9
Ivanovska, Jelena; Zlobec, Inti; Forster, Stefan; Karamitopoulou, Evanthia; Dawson, Heather; Koelzer, Viktor Hendrik; Agaimy, Abbas; Garreis, Fabian; Söder, Stephan; Laqua, William; Lugli, Alessandro; Hartmann, Arndt; Rau, Tilman; Schneider-Stock, Regine (2017). Correction: DAPK loss in colon cancer tumor buds: implications for migration capacity of disseminating tumor cells. OncoTarget, 8(11), pp. 18615-18616. Impact Journals LLC 10.18632/oncotarget.16154
Vinzens Burgener, Sarah Maria; Zindel, Joel; Zweifel, Martin; Rau, Tilman; Gloor, Beat; Wochner, Annette (2017). Granulocyte Colony-stimulating Factor Producing Anaplastic Carcinoma of the Pancreas: Case Report and Review of the Literature. Anticancer research, 37(1), pp. 223-228. International Inst. of Anticancer Research 10.21873/anticanres.11310
Nolte, Sarah; Zlobec, Inti; Lugli, Alessandro; Hohenberger, Werner; Croner, Roland; Merkel, Susanne; Hartmann, Arndt; Geppert, Carol I; Rau, Tilman (2017). Construction and analysis of tissue microarrays in the era of digital pathology: a pilot study targeting CDX1 and CDX2 in a colon cancer cohort of 612 patients. The journal of pathology: clinical research, 3(1), pp. 58-70. Wiley 10.1002/cjp2.62
Rau, Tilman (2016). [Pathogenetic aspects in precursor lesions of gastrointestinal tumors]. Der Pathologe, 37(Suppl2), pp. 186-190. Springer 10.1007/s00292-016-0220-6
Luedeke, Manuel; Rinckleb, Antje E; FitzGerald, Liesel M; Geybels, Milan S; Schleutker, Johanna; Eeles, Rosalind A; Teixeira, Manuel R; Cannon-Albright, Lisa; Ostrander, Elaine A; Weikert, Steffen; Herkommer, Kathleen; Wahlfors, Tiina; Visakorpi, Tapio; Leinonen, Katri A; Tammela, Teuvo L J; Cooper, Colin S; Kote-Jarai, Zsofia; Edwards, Sandra; Goh, Chee L; McCarthy, Frank; ... (2016). Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status. Human molecular genetics, 25(24), pp. 5490-5499. Oxford University Press 10.1093/hmg/ddw349
Galon, J; Fox, B A; Bifulco, C B; Masucci, G; Rau, Tilman; Botti, G; Marincola, F M; Ciliberto, G; Pages, F; Ascierto, P A; Capone, M (2016). Immunoscore and Immunoprofiling in cancer: an update from the melanoma and immunotherapy bridge 2015. Journal of translational medicine, 14(273), p. 273. BioMed Central 10.1186/s12967-016-1029-z
Schey, R; Dornhoff, H; Baier, J L C; Purtak, M; Opoka, R; Koller, A K; Atreya, R; Rau, Tilman; Daniel, C; Amann, K; Bogdan, C; Mattner, J (2016). CD101 inhibits the expansion of colitogenic T cells. Mucosal immunology, 9(5), pp. 1205-1217. Nature Publishing Group 10.1038/mi.2015.139
Rau, Tilman; Atreya, Raja; Aust, Daniela; Baretton, Gustavo; Eck, Matthias; Erlenbach-Wünsch, Katharina; Hartmann, Arndt; Lugli, Alessandro; Stöhr, Robert; Vieth, Michael; Wirsing, Anna M; Zlobec, Inti; Katzenberger, Tiemo (2016). Inflammatory response in serrated precursor lesions of the colon classified according to WHO entities, clinical parameters and phenotype-genotype correlation. The journal of pathology: clinical research, 2(2), pp. 113-124. Wiley 10.1002/cjp2.41
Schmidt, Thomas P; Perna, Anna M; Fugmann, Tim; Böhm, Manja; Hiss, Jan; Haller, Sarah; Götz, Camilla; Tegtmeyer, Nicole; Hoy, Benjamin; Rau, Tilman; Neri, Dario; Backert, Steffen; Schneider, Gisbert; Wessler, Silja (2016). Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA. Scientific Reports, 6(23264), p. 23264. Nature Publishing Group 10.1038/srep23264
Croner, Roland S; Sevim, Müzeyyen; Metodiev, Metodi V; Jo, Peter; Ghadimi, Michael; Schellerer, Vera; Brunner, Maximillian; Geppert, Carol; Rau, Tilman; Stürzl, Michael; Naschberger, Elisabeth; Matzel, Klaus E; Hohenberger, Werner; Lottspeich, Friedrich; Kellermann, Josef (2016). Identification of Predictive Markers for Response to Neoadjuvant Chemoradiation in Rectal Carcinomas by Proteomic Isotope Coded Protein Label (ICPL) Analysis. International journal of molecular sciences, 17(2), p. 209. MDPI 10.3390/ijms17020209
Mager, Lukas; Wasmer, Marie-Hélène; Rau, Tilman; Krebs, Philippe (2016). Cytokine-Induced Modulation of Colorectal Cancer. Frontiers in oncology, 6(96), p. 96. Frontiers Research Foundation 10.3389/fonc.2016.00096
Feiersinger, Fabian; Nolte, Elke; Wach, Sven; Rau, Tilman; Vassos, Nikolaos; Geppert, Carol; Konrad, Andreas; Merkel, Susanne; Taubert, Helge; Stürzl, Michael; Croner, Roland S (2016). MiRNA-21 Expression Decreases from Primary Tumors to Liver Metastases in Colorectal Carcinoma. PLoS ONE, 11(2), e0148580. Public Library of Science 10.1371/journal.pone.0148580
Naschberger, E.; Liebl, A.; Schellerer, V. S.; Schutz, M.; Britzen-Laurent, N.; Kolbel, P.; Schaal, U.; Haep, L.; Regensburger, D.; Wittmann, T.; Klein-Hitpass, L.; Rau, Tilman; Dietel, B.; Meniel, V. S.; Clarke, A. R.; Merkel, S.; Croner, R. S.; Hohenberger, W.; Sturzl, M. (2016). Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinoma. Journal of clinical investigation, 126(11), pp. 4187-4204. American Society for Clinical Investigation 10.1172/JCI78260
Ivanovska, Jelena; Zlobec, Inti; Forster, Stefan; Karamitopoulou, Evanthia; Dawson, Heather; Kölzer, Viktor; Agaimy, Abbas; Garreis, Fabian; Söder, Stephan; Laqua, William; Lugli, Alessandro; Hartmann, Arndt; Rau, Tilman; Schneider-Stock, Regine (2015). DAPK loss in colon cancer tumor buds: implications for migration capacity of disseminating tumor cells. OncoTarget, 6(34), pp. 36774-36788. Impact Journals LLC 10.18632/oncotarget.4908
Raithel, Martin; Rau, Tilman; Hagel, Alexander F; Albrecht, Heinz; de Rossi, Thomas; Kirchner, Thomas; Hahn, Eckhart G (2015). Jejunitis and brown bowel syndrome with multifocal carcinogenesis of the small bowel. World journal of gastroenterology, 21(36), pp. 10461-10467. WJG Press 10.3748/wjg.v21.i36.10461
Foersch, Sebastian; Sperka, Tobias; Lindner, Christina; Taut, Astrid; Rudolph, Karl L; Breier, Georg; Boxberger, Frank; Rau, Tilman; Hartmann, Arndt; Stürzl, Michael; Wittkopf, Nadine; Haep, Lisa; Wirtz, Stefan; Neurath, Markus F; Waldner, Maximilian J (2015). VEGFR2 Signaling Prevents Colorectal Cancer Cell Senescence to Promote Tumorigenesis in Mice With Colitis. Gastroenterology, 149(1), 177-189.e10. Elsevier 10.1053/j.gastro.2015.03.016
Benderska, Natalya; Dittrich, Anna-Lena; Knaup, Sabine; Rau, Tilman; Neufert, Clemens; Wach, Sven; Fahlbusch, Fabian B; Rauh, Manfred; Wirtz, Ralph M; Agaimy, Abbas; Srinivasan, Swetha; Mahadevan, Vijayalakshmi; Rümmele, Petra; Rapti, Emmanouela; Gazouli, Maria; Hartmann, Arndt; Schneider-Stock, Regine (2015). miRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis. Inflammatory bowel diseases, 21(9), pp. 2039-2051. Lippincott Williams & Wilkins 10.1097/MIB.0000000000000453
Bachmann, Leonhard; Besendörfer, Manuel; Carbon, Roman; Lux, Philipp; Agaimy, Abbas; Hartmann, Arndt; Rau, Tilman (2015). Immunohistochemical panel for the diagnosis of Hirschsprung's disease using antibodies to MAP2, calretinin, GLUT1 and S100. Histopathology, 66(6), pp. 824-835. Blackwell Scientific Publications 10.1111/his.12527
Nalleweg, Nancy; Chiriac, Mircea Teodor; Podstawa, Eva; Lehmann, Christian; Rau, Tilman; Atreya, Raja; Krauss, Ekaterina; Hundorfean, Gheorghe; Fichtner-Feigl, Stefan; Hartmann, Arndt; Becker, Christoph; Mudter, Jonas (2015). IL-9 and its receptor are predominantly involved in the pathogenesis of UC. Gut, 64(5), pp. 743-755. BMJ Publishing Group 10.1136/gutjnl-2013-305947
Kraus, Cornelia; Rau, Tilman; Lux, Philipp; Erlenbach-Wünsch, Katharina; Löhr, Sabine; Krumbiegel, Mandy; Thiel, Christian T; Stöhr, Robert; Agaimy, Abbas; Croner, Roland S; Stürzl, Michael; Hohenberger, Werner; Hartmann, Arndt; Reis, André (2015). Comprehensive screening for mutations associated with colorectal cancer in unselected cases reveals penetrant and nonpenetrant mutations. International journal of cancer, 136(6), E559-E568. Wiley-Blackwell 10.1002/ijc.29149
Bujok, Krystyna; Glaeser, Hartmut; Schuh, Wolfgang; Rau, Tilman; Schmidt, Ingrid; Fromm, Martin F; Mandery, Kathrin (2015). Interplay between the prostaglandin transporter OATP2A1 and prostaglandin E2-mediated cellular effects. Cellular signalling, 27(3), pp. 663-672. Elsevier 10.1016/j.cellsig.2014.11.027
Sokol, Lena; Kölzer, Viktor; Rau, Tilman; Karamitopoulou, Evanthia; Zlobec, Inti; Lugli, Alessandro (2015). Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer. Journal of translational medicine, 13(279), p. 279. BioMed Central 10.1186/s12967-015-0647-1
Geppert, C-I; Rümmele, P; Sarbia, M; Langer, Rupert; Feith, M; Morrison, L; Pestova, E; Schneider-Stock, R; Hartmann, A; Rau, Tilman (2014). Multi-colour FISH in oesophageal adenocarcinoma-predictors of prognosis independent of stage and grade. British journal of cancer, 110(12), pp. 2985-2995. Nature Publishing Group 10.1038/bjc.2014.238
Rau, Tilman; Agaimy, Abbas; Gehoff, Anastasia; Geppert, Carol; Jung, Klaus; Knobloch, Katharina; Langner, Cord; Lugli, Alessandro; Groenbus-Lurkin, Irene; Nagtegaal, Iris D; Rüschoff, Josef; Saegert, Xavier; Sarbia, Mario; Schneider-Stock, Regine; Vieth, Michael; Zwarthoff, Ellen C; Hartmann, Arndt (2014). Defined morphological criteria allow reliable diagnosis of colorectal serrated polyps and predict polyp genetics. Virchows Archiv, 464(6), pp. 663-672. Springer 10.1007/s00428-014-1569-7