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Akhoundova, Dilara; Rubin, Mark Andrew (2024). The grand challenge of moving cancer whole-genome sequencing into the clinic. Nature medicine, 30(1), pp. 39-40. Nature Publishing Group 10.1038/s41591-023-02697-7
Reyna, Matthew A; Haan, David; Paczkowska, Marta; Verbeke, Lieven P C; Vazquez, Miguel; Kahraman, Abdullah; Pulido-Tamayo, Sergio; Barenboim, Jonathan; Wadi, Lina; Dhingra, Priyanka; Shrestha, Raunak; Getz, Gad; Lawrence, Michael S; Pedersen, Jakob Skou; Rubin, Mark Andrew; Wheeler, David A; Brunak, Søren; Izarzugaza, Jose M G; Khurana, Ekta; Marchal, Kathleen; ... (2020). Pathway and network analysis of more than 2500 whole cancer genomes. Nature communications, 11(1), p. 729. Nature Publishing Group 10.1038/s41467-020-14367-0
Rheinbay, Esther; Nielsen, Morten Muhlig; Abascal, Federico; Wala, Jeremiah A; Shapira, Ofer; Tiao, Grace; Hornshøj, Henrik; Hess, Julian M; Juul, Randi Istrup; Lin, Ziao; Feuerbach, Lars; Sabarinathan, Radhakrishnan; Madsen, Tobias; Kim, Jaegil; Mularoni, Loris; Shuai, Shimin; Lanzos, Andrés; Herrmann, Carl; Maruvka, Yosef E; Shen, Ciyue; ... (2020). Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Nature, 578(7793), pp. 102-111. Springer Nature 10.1038/s41586-020-1965-x
Shen, Michael M; Rubin, Mark Andrew (2019). Prostate Cancer Research at the Crossroads. Cold Spring Harbor perspectives in medicine, 9(7) Cold Spring Harbor Laboratory Press 10.1101/cshperspect.a036277
Karkampouna, Sofia; Grosjean, Joël; Klima, Irena; Genitsch, Vera; Sboner, A.; K. Y. Ng, C.; De Filippo, M.R.; Piscuoglio, S.; Spahn, M.; Rubin, Mark Andrew; Thalmann, G.N.; Kruithof-de Julio, Marianna (2019). Establishment of an androgen-sensitive patient derived xenograft model of prostate cancer. European Urology Supplements, 18(1), e1154. Elsevier 10.1016/S1569-9056(19)30831-0
Boysen, Gunther; Rodrigues, Daniel N; Rescigno, Pasquale; Seed, George; Dolling, David; Riisnaes, Ruth; Crespo, Mateus; Zafeiriou, Zafeiris; Sumanasuriya, Semini; Bianchini, Diletta; Hunt, Joanne; Moloney, Deirdre; Perez-Lopez, Raquel; Tunariu, Nina; Miranda, Susana; Figueiredo, Inês; Ferreira, Ana; Christova, Rossitza; Gil, Veronica; Aziz, Sara; ... (2018). SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity. Clinical cancer research, 24(22), pp. 5585-5593. American Association for Cancer Research 10.1158/1078-0432.CCR-18-0937
Cotter, Kellie Anne; Rubin, Mark Andrew (2018). Sequence of events in prostate cancer. Nature, 560(7720), pp. 557-559. Macmillan Journals Ltd. 10.1038/d41586-018-06029-5
Hopkins, Benjamin D; Pauli, Chantal; Du, Xing; Wang, Diana G; Li, Xiang; Wu, David; Amadiume, Solomon C; Goncalves, Marcus D; Hodakoski, Cindy; Lundquist, Mark R; Bareja, Rohan; Ma, Yan; Harris, Emily M; Sboner, Andrea; Beltran, Himisha; Rubin, Mark Andrew; Mukherjee, Siddhartha; Cantley, Lewis C (2018). Suppression of insulin feedback enhances the efficacy of PI3K inhibitors. Nature, 560(7719), pp. 499-503. Macmillan Journals Ltd. 10.1038/s41586-018-0343-4
Mateo, Joaquin; Cheng, Heather H; Beltran, Himisha; Dolling, David; Xu, Wen; Pritchard, Colin C; Mossop, Helen; Rescigno, Pasquale; Perez-Lopez, Raquel; Sailer, Verena; Kolinsky, Michael; Balasopoulou, Ada; Bertan, Claudia; Nanus, David M; Tagawa, Scott T; Thorne, Heather; Montgomery, Bruce; Carreira, Suzanne; Sandhu, Shahneen; Rubin, Mark Andrew; ... (2018). Clinical Outcome of Prostate Cancer Patients with Germline DNA Repair Mutations: Retrospective Analysis from an International Study. European urology, 73(5), pp. 687-693. Elsevier 10.1016/j.eururo.2018.01.010
Sailer, Verena; Schiffman, Marc H; Kossai, Myriam; Cyrta, Joanna; Beg, Shaham; Sullivan, Brian; Pua, Bradley B; Lee, Kyungmouk Steve; Talenfeld, Adam D; Nanus, David M; Tagawa, Scott T; Robinson, Brian D; Rao, Rema A; Pauli, Chantal; Bareja, Rohan; Beltran, Luis S; Sigaras, Alexandros; Eng, Kenneth Wa; Elemento, Olivier; Sboner, Andrea; ... (2018). Bone biopsy protocol for advanced prostate cancer in the era of precision medicine. Cancer, 124(5), pp. 1008-1015. John Wiley & Sons 10.1002/cncr.31173
Gillessen, Silke; Attard, Gerhardt; Beer, Tomasz M; Beltran, Himisha; Bossi, Alberto; Bristow, Rob; Carver, Brett; Castellano, Daniel; Chung, Byung Ha; Clarke, Noel; Daugaard, Gedske; Davis, Ian D; de Bono, Johann; Borges Dos Reis, Rodolfo; Drake, Charles G; Eeles, Ros; Efstathiou, Eleni; Evans, Christopher P; Fanti, Stefano; Feng, Felix; ... (2018). Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017. European urology, 73(2), pp. 178-211. Elsevier 10.1016/j.eururo.2017.06.002
Shoag, Jonathan; Liu, Deli; Blattner, Mirjam; Sboner, Andrea; Park, Kyung; Deonarine, Lesa; Robinson, Brian D; Mosquera, Juan Miguel; Chen, Yu; Rubin, Mark Andrew; Barbieri, Christopher E (2018). SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG. Journal of clinical investigation, 128(1), pp. 381-386. American Society for Clinical Investigation 10.1172/JCI96551
McNair, Christopher; Xu, Kexin; Mandigo, Amy C; Benelli, Matteo; Leiby, Benjamin; Rodrigues, Daniel; Lindberg, Johan; Gronberg, Henrik; Crespo, Mateus; De Laere, Bram; Dirix, Luc; Visakorpi, Tapio; Li, Fugen; Feng, Felix Y; de Bono, Johann; Demichelis, Francesca; Rubin, Mark Andrew; Brown, Myles; Knudsen, Karen E (2018). Differential impact of RB status on E2F1 reprogramming in human cancer. Journal of clinical investigation, 128(1), pp. 341-358. American Society for Clinical Investigation 10.1172/JCI93566
D'Alfonso, Timothy M; Subramaniyam, Shivakumar; Ginter, Paula S; Mosquera, Juan Miguel; Croyle, Jaclyn; Liu, Yi-Fang; Rubin, Mark Andrew; Shin, Sandra J (2018). Characterization of CD34-deficient myofibroblastomas of the breast. The breast journal, 24(1), pp. 55-61. Wiley 10.1111/tbj.12835
Rubin, Mark Andrew; Demichelis, Francesca (2018). The Genomics of Prostate Cancer: emerging understanding with technologic advances. Modern pathology, 31(S1), S1-11. Nature Publishing Group 10.1038/modpathol.2017.166
Shukla, Shipra; Cyrta, Joanna; Murphy, Devan A; Walczak, Edward G; Ran, Leili; Agrawal, Praveen; Xie, Yuanyuan; Chen, Yuedan; Wang, Shangqian; Zhan, Yu; Li, Dan; Wong, Elissa W P; Sboner, Andrea; Beltran, Himisha; Mosquera, Juan Miguel; Sher, Jessica; Cao, Zhen; Wongvipat, John; Koche, Richard P; Gopalan, Anuradha; ... (2017). Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance. Cancer cell, 32(6), 792-806.e7. Cell Press 10.1016/j.ccell.2017.10.008
Lee, D; Fontugne, J; Gumpeni, N; Park, K; MacDonald, T Y; Robinson, B D; Sboner, A; Rubin, Mark Andrew; Mosquera, J M; Barbieri, C E (2017). Molecular alterations in prostate cancer and association with MRI features. Prostate cancer and prostatic diseases, 20(4), pp. 430-435. Nature 10.1038/pcan.2017.33
Pauli, C; Moch, H; Rubin, Mark Andrew (2017). [Establishment of a living biobank : Improved guidance of precision cancer care with in vitro and in vivo cancer models]. Der Pathologe, 38(Suppl 2), pp. 160-168. Springer 10.1007/s00292-017-0346-1
Wilkes, David C; Sailer, Verena; Xue, Hui; Cheng, Hongwei; Collins, Colin C; Gleave, Martin; Wang, Yuzhuo; Demichelis, Francesca; Beltran, Himisha; Rubin, Mark Andrew; Rickman, David S (2017). A germline FANCA alteration that is associated with increased sensitivity to DNA damaging agents. Cold Spring Harbor molecular case studies, 3(5) Cold Spring Harbor Laboratory Press 10.1101/mcs.a001487
Dai, Xiangpeng; Gan, Wenjian; Li, Xiaoning; Wang, Shangqian; Zhang, Wei; Huang, Ling; Liu, Shengwu; Zhong, Qing; Guo, Jianping; Zhang, Jinfang; Chen, Ting; Shimizu, Kouhei; Beca, Francisco; Blattner, Mirjam; Vasudevan, Divya; Buckley, Dennis L; Qi, Jun; Buser, Lorenz; Liu, Pengda; Inuzuka, Hiroyuki; ... (2017). Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. Nature medicine, 23(9), pp. 1063-1071. Nature Publishing Group 10.1038/nm.4378
Minciacchi, V R; Zijlstra, A; Rubin, Mark Andrew; Di Vizio, D (2017). Extracellular vesicles for liquid biopsy in prostate cancer: where are we and where are we headed? Prostate cancer and prostatic diseases, 20(3), pp. 251-258. Nature 10.1038/pcan.2017.7
Huang, Franklin W; Mosquera, Juan Miguel; Garofalo, Andrea; Oh, Coyin; Baco, Maria; Amin-Mansour, Ali; Rabasha, Bokang; Bahl, Samira; Mullane, Stephanie A; Robinson, Brian D; Aldubayan, Saud; Khani, Francesca; Karir, Beerinder; Kim, Eejung; Chimene-Weiss, Jeremy; Hofree, Matan; Romanel, Alessandro; Osborne, Joseph R; Kim, Jong Wook; Azabdaftari, Gissou; ... (2017). Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations. Cancer discovery, 7(9), pp. 973-983. American Association for Cancer Research 10.1158/2159-8290.CD-16-0960
Wang, Hui; Barbieri, Christopher E; He, Jintang; Gao, Yuqian; Shi, Tujin; Wu, Chaochao; Schepmoes, Athena A; Fillmore, Thomas L; Chae, Sung-Suk; Huang, Dennis; Mosquera, Juan Miguel; Qian, Wei-Jun; Smith, Richard D; Srivastava, Sudhir; Kagan, Jacob; Camp, David G; Rodland, Karin D; Rubin, Mark Andrew; Liu, Tao (2017). Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics. Journal of translational medicine, 15(1), p. 175. BioMed Central 10.1186/s12967-017-1276-7
Sanda, Martin G; Feng, Ziding; Howard, David H; Tomlins, Scott A; Sokoll, Lori J; Chan, Daniel W; Regan, Meredith M; Groskopf, Jack; Chipman, Jonathan; Patil, Dattatraya H; Salami, Simpa S; Scherr, Douglas S; Kagan, Jacob; Srivastava, Sudhir; Thompson, Ian M; Siddiqui, Javed; Fan, Jing; Joon, Aron Y; Bantis, Leonidas E; Rubin, Mark Andrew; ... (2017). Association Between Combined TMPRSS2:ERG and PCA3 RNA Urinary Testing and Detection of Aggressive Prostate Cancer. JAMA oncology, 3(8), pp. 1085-1093. American Medical Association 10.1001/jamaoncol.2017.0177
Dhingra, Priyanka; Martinez-Fundichely, Alexander; Berger, Adeline; Huang, Franklin W; Forbes, Andre Neil; Liu, Eric Minwei; Liu, Deli; Sboner, Andrea; Tamayo, Pablo; Rickman, David S; Rubin, Mark Andrew; Khurana, Ekta (2017). Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network. Genome biology, 18(1), p. 141. BioMed Central Ltd. 10.1186/s13059-017-1266-3
Zou, Min; Toivanen, Roxanne; Mitrofanova, Antonina; Floch, Nicolas; Hayati, Sheida; Sun, Yanping; Le Magnen, Clémentine; Chester, Daniel; Mostaghel, Elahe A; Califano, Andrea; Rubin, Mark Andrew; Shen, Michael M; Abate-Shen, Cory (2017). Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer. Cancer discovery, 7(7), pp. 736-749. American Association for Cancer Research 10.1158/2159-8290.CD-16-1174
O'Malley, Padraic G; Nguyen, Daniel P.; Al Hussein Al Awamlh, Bashir; Wu, Guojiao; Thompson, Ian M; Sanda, Martin; Rubin, Mark Andrew; Wei, John T; Lee, Richard; Christos, Paul; Barbieri, Christopher; Scherr, Douglas S (2017). Racial Variation in the Utility of Urinary Biomarkers PCA3 and T2ERG in a Large Multicenter Study. The journal of urology, 198(1), pp. 42-49. Elsevier 10.1016/j.juro.2017.01.058
Romanel, Alessandro; Garritano, Sonia; Stringa, Blerta; Blattner, Mirjam; Dalfovo, Davide; Chakravarty, Dimple; Soong, David; Cotter, Kellie Anne; Petris, Gianluca; Dhingra, Priyanka; Gasperini, Paola; Cereseto, Anna; Elemento, Olivier; Sboner, Andrea; Khurana, Ekta; Inga, Alberto; Rubin, Mark Andrew; Demichelis, Francesca (2017). Inherited determinants of early recurrent somatic mutations in prostate cancer. Nature communications, 8(1), p. 48. Nature Publishing Group 10.1038/s41467-017-00046-0
Rickman, David S; Beltran, Himisha; Demichelis, Francesca; Rubin, Mark Andrew (2017). Biology and evolution of poorly differentiated neuroendocrine tumors. Nature medicine, 23(6), pp. 664-673. Nature Publishing Group 10.1038/nm.4341
Huang, Linda; Fernandes, Helen; Zia, Hamid; Tavassoli, Peyman; Rennert, Hanna; Pisapia, David; Imielinski, Marcin; Sboner, Andrea; Rubin, Mark Andrew; Kluk, Michael; Elemento, Olivier (2017). The cancer precision medicine knowledge base for structured clinical-grade mutations and interpretations. Journal of the American Medical Informatics Association, 24(3), pp. 513-519. Oxford University Press 10.1093/jamia/ocw148
Imielinski, Marcin; Rubin, Mark Andrew (2017). Prostate cancer: Clinical hallmarks in whole cancer genomes. Nature reviews - clinical oncology, 14(5), pp. 265-266. Nature Publishing Group 10.1038/nrclinonc.2017.45
Pauli, Chantal; Hopkins, Benjamin D; Prandi, Davide; Shaw, Reid; Fedrizzi, Tarcisio; Sboner, Andrea; Sailer, Verena; Augello, Michael; Puca, Loredana; Rosati, Rachele; McNary, Terra J; Churakova, Yelena; Cheung, Cynthia; Triscott, Joanna Catherine Caprio; Pisapia, David; Rao, Rema; Mosquera, Juan Miguel; Robinson, Brian; Faltas, Bishoy M; Emerling, Brooke E; ... (2017). Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine. Cancer discovery, 7(5), pp. 462-477. American Association for Cancer Research 10.1158/2159-8290.CD-16-1154
Sailer, Verena; Pauli, Chantal; Merzier, Elyze C; Mosquera, Juan Miguel; Beltran, Himisha; Rubin, Mark Andrew; Rao, Rema A (2017). On-site Cytology for Development of Patient-Derived Three-dimensional Organoid Cultures - A Pilot Study. Anticancer research, 37(4), pp. 1569-1573. International Inst. of Anticancer Research 10.21873/anticanres.11486
Blattner, Mirjam; Liu, Deli; Robinson, Brian D; Huang, Dennis; Poliakov, Anton; Gao, Dong; Nataraj, Srilakshmi; Deonarine, Lesa D; Augello, Michael A; Sailer, Verena; Ponnala, Lalit; Ittmann, Michael; Chinnaiyan, Arul M; Sboner, Andrea; Chen, Yu; Rubin, Mark Andrew; Barbieri, Christopher E (2017). SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling. Cancer cell, 31(3), pp. 436-451. Cell Press 10.1016/j.ccell.2017.02.004
Mateo, Joaquin; Boysen, Gunther; Barbieri, Christopher E; Bryant, Helen E; Castro, Elena; Nelson, Pete S; Olmos, David; Pritchard, Colin C; Rubin, Mark Andrew; de Bono, Johann S (2017). DNA Repair in Prostate Cancer: Biology and Clinical Implications. European urology, 71(3), pp. 417-425. Elsevier 10.1016/j.eururo.2016.08.037
Barbieri, Christopher E; Chinnaiyan, Arul M; Lerner, Seth P; Swanton, Charles; Rubin, Mark Andrew (2017). The Emergence of Precision Urologic Oncology: A Collaborative Review on Biomarker-driven Therapeutics. European urology, 71(2), pp. 237-246. Elsevier 10.1016/j.eururo.2016.08.024
Villers, Arnauld; Rubin, Mark Andrew (2017). Re: Prognostic Significance of Percentage and Architectural Types of Contemporary Gleason Pattern 4 Prostate Cancer in Radical Prostatectomy. European urology, 71(2), p. 301. Elsevier 10.1016/j.eururo.2016.09.017
Mu, Ping; Zhang, Zeda; Benelli, Matteo; Karthaus, Wouter R; Hoover, Elizabeth; Chen, Chi-Chao; Wongvipat, John; Ku, Sheng-Yu; Gao, Dong; Cao, Zhen; Shah, Neel; Adams, Elizabeth J; Abida, Wassim; Watson, Philip A; Prandi, Davide; Huang, Chun-Hao; de Stanchina, Elisa; Lowe, Scott W; Ellis, Leigh; Beltran, Himisha; ... (2017). SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer. Science, 355(6320), pp. 84-88. American Association for the Advancement of Science 10.1126/science.aah4307
Bishop, Jennifer L; Thaper, Daksh; Vahid, Sepideh; Davies, Alastair; Ketola, Kirsi; Kuruma, Hidetoshi; Jama, Randy; Nip, Ka Mun; Angeles, Arkhjamil; Johnson, Fraser; Wyatt, Alexander W; Fazli, Ladan; Gleave, Martin E; Lin, Dong; Rubin, Mark Andrew; Collins, Colin C; Wang, Yuzhuo; Beltran, Himisha; Zoubeidi, Amina (2017). The Master Neural Transcription Factor BRN2 Is an Androgen Receptor-Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer. Cancer discovery, 7(1), pp. 54-71. American Association for Cancer Research 10.1158/2159-8290.CD-15-1263
Bolis, Marco; Bossi, Daniela; Vallerga, Arianna; Cavalli, Manuela; di Rito, Laura; Zoni, Eugenio; Mosole, Simone; Rinaldi, Andrea; Pereira Mestre, Ricardo; D'Antonio, Eugenia; Ferrari, Matteo; Stoffel, Flavio; Jermini, Fernando; Gillessen Sommer, Silke; Bubendorf, Lukas; Schraml, Peter; Moch, Holger; Spahn, Martin; Thalmann, George; Kruithof-de Julio, Marianna; ... (15 March 2021). Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression. Research Square 10.21203/rs.3.rs-296396/v1
