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Fernbach, Sonja; Mair, Nina K; Abela, Irene A; Groen, Kevin; Kuratli, Roger; Lork, Marie; Thorball, Christian W; Bernasconi, Enos; Filippidis, Paraskevas; Leuzinger, Karoline; Notter, Julia; Rauch, Andri; Hirsch, Hans H; Huber, Michael; Günthard, Huldrych F; Fellay, Jacques; Kouyos, Roger D; Hale, Benjamin G (2024). Loss of tolerance precedes triggering and lifelong persistence of pathogenic type I interferon autoantibodies. Journal of experimental medicine, 221(9) Rockefeller University Press 10.1084/jem.20240365
Neuner-Jehle, Nadia; Zeeb, Marius; Thorball, Christian W; Fellay, Jacques; Metzner, Karin J; Frischknecht, Paul; Neumann, Kathrin; Leeman, Christine; Rauch, Andri; Stöckle, Marcel; Huber, Michael; Perreau, Matthieu; Bernasconi, Enos; Notter, Julia; Hoffmann, Matthias; Leuzinger, Karoline; Günthard, Huldrych F; Pasin, Chloé; Kouyos, Roger D (2024). Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen. PLoS pathogens, 20(8), e1012385. Public Library of Science 10.1371/journal.ppat.1012385
Schwenke, Johannes M; Thorball, Christian W; Schöpf, Isabella C; Ryom, Lene; Hasse, Barbara; Lamy, Olivier; Calmy, Alexandra; Wandeler, Gilles; Marzolini, Catia; Kahlert, Christian R; Bernasconi, Enos; Kouyos, Roger; Günthard, Huldrych F; Ledergerber, Bruno; Fellay, Jacques; Burkhalter, Felix; Tarr, Philip E (2023). Association of a Polygenic Risk Score with Osteoporosis in People Living with HIV: The Swiss HIV Cohort Study. The journal of infectious diseases, 228(6), pp. 742-750. Oxford University Press 10.1093/infdis/jiad179
McLaren, Paul J; Porreca, Immacolata; Iaconis, Gennaro; Mok, Hoi Ping; Mukhopadhyay, Subhankar; Karakoc, Emre; Cristinelli, Sara; Pomilla, Cristina; Bartha, István; Thorball, Christian W; Tough, Riley H; Angelino, Paolo; Kiar, Cher S; Carstensen, Tommy; Fatumo, Segun; Porter, Tarryn; Jarvis, Isobel; Skarnes, William C; Bassett, Andrew; DeGorter, Marianne K; ... (2023). Author Correction: Africa-specific human genetic variation near CHD1L associates with HIV-1 load. Nature, 621(7979), E42. Springer Nature 10.1038/s41586-023-06591-7
McLaren, Paul J; Porreca, Immacolata; Iaconis, Gennaro; Mok, Hoi Ping; Mukhopadhyay, Subhankar; Karakoc, Emre; Cristinelli, Sara; Pomilla, Cristina; Bartha, István; Thorball, Christian W; Tough, Riley H; Angelino, Paolo; Kiar, Cher S; Carstensen, Tommy; Fatumo, Segun; Porter, Tarryn; Jarvis, Isobel; Skarnes, William C; Bassett, Andrew; DeGorter, Marianne K; ... (2023). Africa-specific human genetic variation near CHD1L associates with HIV-1 load. Nature, 620(7976), pp. 1025-1030. Springer Nature 10.1038/s41586-023-06370-4
Avery, Emma F; Kleynhans, Julia N; Ledergerber, Bruno; Schoepf, Isabella C; Thorball, Christian W; Kootstra, Neeltje A; Reiss, Peter; Ryom, Lene; Braun, Dominique L; Thurnheer, Maria C; Marzolini, Catia; Seneghini, Marco; Bernasconi, Enos; Cavassini, Matthias; Buvelot, Hélène; Kouyos, Roger D; Fellay, Jacques; Günthard, Huldrych F; Tarr, Philip E (2023). Leukocyte Count and Coronary Artery Disease Events in People with HIV: A Longitudinal Study. Clinical infectious diseases, 76(11), pp. 1969-1979. Oxford University Press 10.1093/cid/ciad033
Schoepf, Isabella C; Esteban-Cantos, Andrés; Thorball, Christian W; Rodés, Berta; Reiss, Peter; Rodríguez-Centeno, Javier; Riebensahm, Carlotta; Braun, Dominique L; Marzolini, Catia; Seneghini, Marco; Bernasconi, Enos; Cavassini, Matthias; Buvelot, Hélène; Thurnheer, Maria Christine; Kouyos, Roger D; Fellay, Jacques; Günthard, Huldrych F; Arribas, José R; Ledergerber, Bruno and Tarr, Philip E (2023). Epigenetic ageing accelerates before antiretroviral therapy and decelerates after viral suppression in people with HIV in Switzerland: a longitudinal study over 17 years. The Lancet. Healthy longevity, 4(5), e211-e218. Elsevier 10.1016/S2666-7568(23)00037-5
Schoepf, Isabella C; Thorball, Christian W; Kovari, Helen; Ledergerber, Bruno; Buechel, Ronny R; Calmy, Alexandra; Weber, Rainer; Kaufmann, Philipp A; Nkoulou, René; Schwenke, Johannes M; Braun, Dominique L; Fellay, Jacques; Tarr, Philip E (2023). Polygenic Risk Scores for Prediction of Subclinical Coronary Artery Disease in Persons Living with HIV: The Swiss HIV Cohort Study. Clinical infectious diseases, 76(1), pp. 48-56. Oxford University Press 10.1093/cid/ciac758
Nadeau, Sarah; Thorball, Christian W; Kouyos, Roger; Günthard, Huldrych F; Böni, Jürg; Yerly, Sabine; Perreau, Matthieu; Klimkait, Thomas; Rauch, Andri; Hirsch, Hans H; Cavassini, Matthias; Vernazza, Pietro; Bernasconi, Enos; Fellay, Jacques; Mitov, Venelin; Stadler, Tanja (2022). A phylogeny-aware GWAS framework to correct for heritable pathogen effects on infectious disease traits. Molecular Biology and Evolution, 39(8) Oxford University Press 10.1093/molbev/msac163
Bick, Alexander G; Popadin, Konstantin; Thorball, Christian W; Uddin, Md Mesbah; Zanni, Markella V; Yu, Bing; Cavassini, Matthias; Rauch, Andri; Tarr, Philip; Schmid, Patrick; Bernasconi, Enos; Günthard, Huldrych F; Libby, Peter; Boerwinkle, Eric; McLaren, Paul J; Ballantyne, Christie M; Grinspoon, Steven; Natarajan, Pradeep; Fellay, Jacques (2022). Author Correction: Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV. Scientific Reports, 12(1), p. 11638. Nature Publishing Group 10.1038/s41598-022-16151-0
Schoepf, Isabella C; Thorball, Christian W; Ledergerber, Bruno; Kootstra, Neeltje A; Reiss, Peter; Raffenberg, Marieke; Engel, Tanja; Braun, Dominique L; Hasse, Barbara; Thurnheer, Christine; Marzolini, Catia; Seneghini, Marco; Bernasconi, Enos; Cavassini, Matthias; Buvelot, Hélène; Arribas, José R; Kouyos, Roger D; Fellay, Jacques; Günthard, Huldrych F and Tarr, Philip E (2022). Telomere Length Declines In Persons Living With HIV Before Antiretroviral Therapy Start But Not After Viral Suppression: A Longitudinal Study Over >17 Years. The journal of infectious diseases, 225(9), pp. 1581-1591. Oxford University Press 10.1093/infdis/jiab603
Bick, Alexander G; Popadin, Konstantin; Thorball, Christian W; Uddin, Md Mesbah; Zanni, Markella V; Yu, Bing; Cavassini, Matthias; Rauch, Andri; Tarr, Philip; Schmid, Patrick; Bernasconi, Enos; Günthard, Huldrych F; Libby, Peter; Boerwinkle, Eric; McLaren, Paul J; Ballantyne, Christie M; Grinspoon, Steven; Natarajan, Pradeep; Fellay, Jacques (2022). Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV. Scientific reports, 12(1), p. 577. Springer Nature 10.1038/s41598-021-04308-2
Schoepf, Isabella C; Thorball, Christian W; Ledergerber, Bruno; Engel, Tanja; Raffenberg, Marieke; Kootstra, Neeltje A; Reiss, Peter; Hasse, Barbara; Marzolini, Catia; Thurnheer, Christine; Seneghini, Marco; Bernasconi, Enos; Cavassini, Matthias; Buvelot, Hélène; Kouyos, Roger; Günthard, Huldrych F; Fellay, Jacques; Tarr, Philip E (2021). Coronary Artery Disease–Associated and Longevity-Associated Polygenic Risk Scores for Prediction of Coronary Artery Disease Events in Persons Living With Human Immunodeficiency Virus: The Swiss HIV Cohort Study. Clinical infectious diseases, 73(9), pp. 1597-1604. The University of Chicago Press 10.1093/cid/ciab521
Engel, Tanja; Raffenberg, Marieke; Schoepf, Isabella C; Kootstra, Neeltje A; Reiss, Peter; Thorball, Christian W; Hasse, Barbara; Hirzel, Cédric; Wissel, Kerstin; Roth, Jan A; Bernasconi, Enos; Darling, Katharine E A; Calmy, Alexandra; Fellay, Jacques; Kouyos, Roger D; Günthard, Huldrych F; Ledergerber, Bruno; Tarr, Philip E (2021). Telomere Length, Traditional Risk Factors, HIV-related Factors and Coronary Artery Disease Events in Swiss Persons Living with HIV. Clinical infectious diseases, 73(7), e2070-e2076. Oxford University Press 10.1093/cid/ciaa1034
Thorball, Christian W; Oudot-Mellakh, Tiphaine; Ehsan, Nava; Hammer, Christian; Santoni, Federico A; Niay, Jonathan; Costagliola, Dominique; Goujard, Cécile; Meyer, Laurence; Wang, Sophia S; Hussain, Shehnaz K; Theodorou, Ioannis; Cavassini, Matthias; Rauch, Andri; Battegay, Manuel; Hoffmann, Matthias; Schmid, Patrick; Bernasconi, Enos; Günthard, Huldrych F; Mohammadi, Pejman; ... (2021). Genetic variation near CXCL12 is associated with susceptibility to HIV-related non-Hodgkin lymphoma. Haematologica - the hematology journal, 106(8), pp. 2233-2241. Ferrata-Storti Foundation 10.3324/haematol.2020.247023
Dietrich, Léna G; Thorball, Christian W; Ryom, Lene; Burkhalter, Felix; Hasse, Barbara; Thurnheer, Maria Christine; Weisser, Maja; Schmid, Patrick; Bernasconi, Enos; Darling, Kathrine E A; Buvelot, Hélène; Fellay, Jacques; Ledergerber, Bruno; Tarr, Philip E (2021). Rapid Progression of Kidney Dysfunction in Swiss People Living with HIV: Contribution of Polygenic Risk Score and D:A:D Clinical Risk Score. The journal of infectious diseases, 223(12), pp. 2145-2153. Oxford University Press 10.1093/infdis/jiaa695
Borghesi, Alessandro; Trück, Johannes; Asgari, Samira; Sancho-Shimizu, Vanessa; Agyeman, Philipp KA; Bellos, Evangelos; Giannoni, Eric; Stocker, Martin; Posfay-Barbe, Klara M; Heininger, Ulrich; Bernhard-Stirnemann, Sara; Niederer-Loher, Anita; Kahlert, Christian R; Natalucci, Giancardlo; Relly, Christa; Riedel, Thomas; Kuehni, Claudia E; Thorball, Christian W; Chaturvedi, Nimisha; Martinon-Torres, Federico; ... (2020). Whole-exome sequencing for the identification of rare variants in primary immunodeficiency genes in children with sepsis - a prospective population-based cohort study. Clinical infectious diseases, 71(10), e614-e623. The University of Chicago Press 10.1093/cid/ciaa290
Thorball, Christian W; Borghesi, Alessandro; Bachmann, Nadine; Von Siebenthal, Chantal; Vongrad, Valentina; Turk, Teja; Neumann, Kathrin; Beerenwinkel, Niko; Bogojeska, Jasmina; Roth, Volker; Kok, Yik Lim; Parbhoo, Sonali; Wieser, Mario; Böni, Jürg; Perreau, Matthieu; Klimkait, Thomas; Yerly, Sabine; Battegay, Manuel; Rauch, Andri; Schmid, Patrick; ... (2020). Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment. Journal of acquired immune deficiency syndromes, 85(4), pp. 517-524. Wolters Kluwer Health 10.1097/QAI.0000000000002473
Dietrich, Léna G; Barceló, Catalina; Thorball, Christian W; Ryom, Lene; Burkhalter, Felix; Hasse, Barbara; Furrer, Hansjakob; Weisser, Maja; Steffen, Ana; Bernasconi, Enos; Cavassini, Matthias; de Seigneux, Sophie; Csajka, Chantal; Fellay, Jacques; Ledergerber, Bruno; Tarr, Philip E (2020). Contribution of genetic background and clinical D:A:D risk score to chronic kidney disease in Swiss HIV-positive persons with normal baseline estimated glomerular filtration rate. Clinical infectious diseases, 70(5), pp. 890-897. Oxford University Press 10.1093/cid/ciz280
Barceló, Catalina; Guidi, Monia; Thorball, Christian W; Hammer, Christian; Chaouch, Aziz; Scherrer, Alexandra U; Hasse, Barbara; Cavassini, Matthias; Furrer, Hansjakob; Calmy, Alexandra; Haubitz, Sebastian; Bernasconi, Enos; Buclin, Thierry; Fellay, Jacques; Tarr, Philip E; Csajka, Chantal (2020). Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy. Open Forum Infectious Diseases, 7(1), ofz464. Oxford University Press 10.1093/ofid/ofz464
Nguyen, Huyen; Thorball, Christian W; Fellay, Jacques; Böni, Jürg; Yerly, Sabine; Perreau, Matthieu; Klimkait, Thomas; Kusjeko, Katharina; Bachmann, Nadine; Chaudron, Sandra E; Paioni, Paolo; Thurnheer Zürcher, Maria Christine; Battegay, Manuel; Cavassini, Matthias; Vernazza, Pietro; Bernasconi, Enos; Günthard, Huldrych F; Kouyos, Roger (2019). HIV transmission chains exhibit greater HLA-B homogeneity than randomly expected. Journal of acquired immune deficiency syndromes JAIDS, 81(5), pp. 508-515. Lippincott Williams & Wilkins 10.1097/QAI.0000000000002077
Bachmann, Nadine; von Siebenthal, Chantal; Vongrad, Valentina; Turk, Teja; Neumann, Kathrin; Beerenwinkel, Niko; Bogojeska, Jasmina; Fellay, Jaques; Roth, Volker; Kok, Yik Lim; Thorball, Christian W; Borghesi, Alessandro; Parbhoo, Sonali; Wieser, Mario; Böni, Jürg; Perreau, Matthieu; Klimkait, Thomas; Yerly, Sabine; Battegay, Manuel; Rauch, Andri; ... (2019). Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART. Nature communications, 10(1), pp. 1-11. Nature Publishing Group 10.1038/s41467-019-10884-9
Rusert, Peter; Kouyos, Roger D; Kadelka, Claus; Ebner, Hanna; Schanz, Merle; Huber, Michael; Braun, Dominique L; Hozé, Nathanael; Scherrer, Alexandra; Magnus, Carsten; Weber, Jacqueline; Uhr, Therese; Cippa, Valentina; Thorball, Christian W; Kuster, Herbert; Cavassini, Matthias; Bernasconi, Enos; Hoffmann, Matthias; Calmy, Alexandra; Battegay, Manuel; ... (2016). Determinants of HIV-1 broadly neutralizing antibody induction. Nature medicine, 22(11), pp. 1260-1267. Nature Publishing Group 10.1038/nm.4187
Bick, Alexander G; Popadin, Konstantin; Thorball, Christian W; Uddin, Md Mesbah; Zanni, Markella; Yu, Bing; Cavassini, Matthias; Rauch, Andri; Tarr, Philip; Schmid, Patrick; Bernasconi, Enos; Gunthard, Huldrych; Libby, Peter; Boerwinkle, Eric; McLaren, Paul; Ballantyne, Christie M; Grinspoon, Steven K; Natarajan, Pradeep; Fellay, Jacques (7 November 2020). Increased CHIP Prevalence Amongst People Living with HIV. (medRxiv). Cold Spring Harbor Laboratory 10.1101/2020.11.06.20225607
