Schürch, Christian

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2016

Riether, Carsten; Schürch, Christian M.; Bührer, Elias D.; Hinterbrandner, Magdalena; Huguenin, Anne-Laure; Höpner, Sabine; Zlobec, Inti; Pabst, Thomas; Radpour, Ramin; Ochsenbein, Adrian F. (2016). CD70/CD27 signaling promotes blast stemness and is a viable therapeutic target in acute myeloid leukemia. The Journal of experimental medicine, 214(2), pp. 359-380. Rockefeller Univ. Press 10.1084/jem.20152008

Studer, Nicolas; Desharnais, Lyne; Beutler, Markus; Brugiroux, Sandrine; Terrazos Miani, Miguel Angel; Menin, Laure; Schürch, Christian; McCoy, Kathy D.; Kuehne, Sarah A.; Minton, Nigel P.; Stecher, Bärbel; Bernier-Latmani, Rizlan; Hapfelmeier, Siegfried Hektor (2016). Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model. Frontiers in Cellular and Infection Microbiology, 6, p. 191. Frontiers 10.3389/fcimb.2016.00191

2015

Riether, Carsten; Gschwend, T; Huguenin, Anne-Laure; Schürch, Christian; Ochsenbein, Adrian (2015). Blocking programmed cell death 1 in combination with adoptive cytotoxic T-cell transfer eradicates chronic myelogenous leukemia stem cells. Leukemia, 29(8), pp. 1781-1785. Nature Publishing Group 10.1038/leu.2015.26

Riether, Carsten; Schürch, Christian; Flury, Christoph; Hinterbrandner, Magdalena; Drück, Linda; Huguenin, Anne-Laure; Baerlocher, Gabriela M.; Radpour, Ramin; Ochsenbein, Adrian (2015). Tyrosine kinase inhibitor-induced CD70 expression mediates drug resistance in leukemia stem cells by activating Wnt signaling. Science translational medicine, 7(298), 298ra119. American Association for the Advancement of Science 10.1126/scitranslmed.aab1740

Mager, Lukas; Riether, Carsten; Schürch, Christian; Banz Wälti, Yara; Wasmer, Marie-Hélène Christin; Stuber Roos, Regula; Theocharides, Alexandre; Li, Xiaohong; Xia, Yu; Saito, Hirohisa; Nakae, Susumu; Baerlocher, Gabriela M.; Manz, Markus G; McCoy, Kathleen; Macpherson, Andrew; Macpherson, Andrew; Ochsenbein, Adrian; Beutler, Bruce; Krebs, Philippe (2015). IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms. Journal of clinical investigation, 125(7), pp. 2579-2591. American Society for Clinical Investigation 10.1172/JCI77347

Galli, Serena; Zlobec, Inti; Schürch, Christian; Perren, Aurel; Ochsenbein, Adrian; Banz Wälti, Yara (2015). CD47 protein expression in acute myeloid leukemia: A tissue microarray-based analysis. Leukemia research, 39(7), pp. 749-756. Elsevier 10.1016/j.leukres.2015.04.007

Riether, Carsten; Schürch, Christian; Ochsenbein, Adrian (2015). Regulation of hematopoietic and leukemic stem cells by the immune system. Cell death and differentiation, 22(2), pp. 187-198. Nature Publishing Group 10.1038/cdd.2014.89

2014

Balmer, Maria L; Schürch, Christian; Saito, Yasuyuki; Geuking, Markus; Li, Hai; Cuenca, Miguelangel; Kovtonyuk, Larisa V; McCoy, Kathleen; Hapfelmeier, Siegfried; Ochsenbein, Adrian; Manz, Markus G; Slack, Emma; Macpherson, Andrew (2014). Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling. Journal of immunology, 193(10), pp. 5273-5283. American Association of Immunologists 10.4049/jimmunol.1400762

Schürch, Christian; Riether, Carsten; Ochsenbein, Adrian (2014). Cytotoxic CD8+ T cells stimulate hematopoietic progenitors by promoting cytokine release from bone marrow mesenchymal stromal cells. Cell stem cell, 14(4), pp. 460-472. Elsevier 10.1016/j.stem.2014.01.002

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

2013

Schürch, Christian M.; Riether, Carsten; Ochsenbein, Adrian F. (2013). Dendritic Cell-Based Immunotherapy for Myeloid Leukemias. Frontiers in immunology, 4(496), p. 496. Frontiers Research Foundation 10.3389/fimmu.2013.00496

Schürch, Christian M.; Riether, Carsten; Ochsenbein, Adrian F. (2013). Interferons in hematopoiesis and leukemia. Oncoimmunology, 2(6), e24572. Landes Bioscience 10.4161/onci.24572

Schürch, Christian; Birrer, Michèle Andrea; Estella, Isabelle; Kappeler, Andreas; Hewer, Ekkehard; Vajtai, Istvan (2013). "Leiomyomatoid angiomatous neuroendocrine tumor" (LANT) of the pituitary reflects idiosyncratic angiogenesis in adenomas of the gonadotroph cell lineage. Pathology, research and practice, 209(3), pp. 155-160. Elsevier 10.1016/j.prp.2013.01.003

Schürch, Christian; Riether, Carsten; Amrein, Michael A.; Ochsenbein, Adrian F. (2013). Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ. Journal of experimental medicine, 210(3), pp. 605-621. Rockefeller University Press 10.1084/jem.20121229

Riether, Carsten; Schürch, Christian; Ochsenbein, Adrian F. (2013). From "magic bullets" to specific cancer immunotherapy. Swiss medical weekly, 143, w13734. EMH Schweizerischer Ärzteverlag 10.4414/smw.2013.13734

Galli, S.; Schürch, C.; Zlobec, I.; Perren, A.; Banz Wälti, Y. (2013). Analysis of CD47 expression in acute myeloid leukemia in a bone marrow tissue microarray. Pathologe, 34(6), p. 608. Springer-Medizin-Verlag

2012

Schürch, Christian; Riether, Carsten; Matter, Matthias S; Tzankov, Alexandar; Ochsenbein, Adrian (2012). CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression. Journal of clinical investigation, 122(2), pp. 624-38. Ann Arbor, Mich.: American Society for Clinical Investigation 10.1172/JCI45977

Riether, Carsten; Schürch, Christian; Ochsenbein, Adrian (2012). Modulating CD27 signaling to treat cancer. Oncoimmunology, 1(9), pp. 1604-1606. Austin, Tex.: Landes Bioscience 10.4161/onci.21425

Claus, Christina; Riether, Carsten; Schürch, Christian; Matter, Matthias S; Hilmenyuk, Tamara; Ochsenbein, Adrian (2012). CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth. Cancer research, 72(14), pp. 3664-76. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-11-2791

2011

Matter, Matthias S; Hilmenyuk, Tamara; Claus, Christina; Marone, Romina; Schürch, Christian; Tinguely, Marianne; Terracciano, Luigi; Luther, Sanjiv A; Ochsenbein, Adrian (2011). Destruction of lymphoid organ architecture and hepatitis caused by CD4+ T cells. PLoS ONE, 6(9), e24772. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0024772

2010

Mumprecht, Sabine Barbara; Schürch, Christian; Scherrer, Sandro; Claus, Christina; Ochsenbein, Adrian (2010). Chronic myelogenous leukemia maintains specific CD8(+) T cells through IL-7 signaling. European journal of immunology, 40(10), pp. 2720-2730. Weinheim: Wiley-VCH 10.1002/eji.201040404

2009

Mumprecht, Sabine Barbara; Schürch, Christian; Schwaller, Juerg; Solenthaler, Max; Ochsenbein, Adrian F (2009). Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression. Blood, 114(8), pp. 1528-1536. Washington, D.C.: American Society of Hematology 10.1182/blood-2008-09-179697

Mumprecht, Sabine; Claus, Christina; Schürch, Christian; Pavelic, Viktor; Matter, Matthias S; Ochsenbein, Adrian F (2009). Defective homing and impaired induction of cytotoxic T cells by BCR/ABL-expressing dendritic cells. Blood, 113(19), pp. 4681-9. Washington, D.C.: American Society of Hematology 10.1182/blood-2008-05-156471

2007

Grandgirard, Denis; Schürch, Christian; Cottagnoud, Philippe; Leib, Stephen L. (2007). Prevention of brain injury by the nonbacteriolytic antibiotic daptomycin in experimental pneumococcal meningitis. Antimicrobial agents and chemotherapy, 51(6), pp. 2173-2178. Washington, D.C.: American Society for Microbiology 10.1128/AAC.01014-06

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