Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis.

Flohr, Sarah; Ramette, Alban; Agyeman, Philipp K. A.; Duppenthaler, Andrea; Scherer, Cordula; Keller, Peter M.; Aebi, Christoph (2020). Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis. Open Forum Infectious Diseases, 7(11), ofaa506. Oxford University Press 10.1093/ofid/ofaa506

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Mycobacterium chelonae infections usually resolve with adequate therapy. We report the case of an adolescent with a chronic and progressive M chelonae infection refractory to combined antimicrobial and surgical therapy. Whole genome sequence analysis of consecutive isolates distinguished reinfection from recurrence and contributed to the diagnosis of a factitious disorder.

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