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Campos-Madueno, Edgar I.; Gmuer, Christian; Risch, Martin; Bodmer, Thomas; Endimiani, Andrea (2021). Characterization of a new blaVIM-1-carrying IncN2 plasmid from an Enterobacter hormaechei subsp. steigerwaltii. Journal of global antimicrobial resistance, 24, pp. 325-327. Elsevier 10.1016/j.jgar.2021.01.017
Egli, Konrad; Wagner, Karoline; Keller, Peter M.; Risch, Lorenz; Risch, Martin; Bodmer, Thomas (2020). Comparison of the Diagnostic Performance of qPCR, Sanger Sequencing, and Whole-Genome Sequencing in Determining Clarithromycin and Levofloxacin Resistance in Helicobacter pylori. Frontiers in cellular and infection microbiology, 10(596371), p. 596371. Frontiers 10.3389/fcimb.2020.596371
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Hilty, Markus; Wüthrich, Tsering M.; Godel, Aurélie; Adelfio, Roberto; Aebi, Susanne; Burgener, Sabrina S.; Illgen-Wilcke, Brunhilde; Benarafa, Charaf (2020). Chronic cigarette smoke exposure and pneumococcal infection induce oropharyngeal microbiota dysbiosis and contribute to long-lasting lung damage in mice. Microbial genomics, 6(12) Microbiology Society 10.1099/mgen.0.000485
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Büdel, Thomas; Kuenzli, Esther; Campos-Madueno, Edgar I; Mohammed, Ali Haji; Hassan, Nadir Khatib; Zinsstag, Jakob; Hatz, Christoph; Endimiani, Andrea (2020). On the island of Zanzibar people in the community are frequently colonized with the same MDR Enterobacterales found in poultry and retailed chicken meat. The journal of antimicrobial chemotherapy, 75(9), pp. 2432-2441. Oxford University Press 10.1093/jac/dkaa198
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Pan, Steven D.; Grandgirard, Denis; Leib, Stephen L. (2020). Adjuvant Cannabinoid Receptor Type 2 Agonist Modulates the Polarization of Microglia Towards a Non-Inflammatory Phenotype in Experimental Pneumococcal Meningitis. Frontiers in cellular and infection microbiology, 10 Frontiers 10.3389/fcimb.2020.588195
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Krämer, Julia; Do Couto Pires, Joao Pedro; Küffer, Marianne; Semaani, Eulalia; Endimiani, Andrea; Hilty, Markus; Oppliger, Anne (2017). Prevalence of extended-spectrum β-lactamase-producing Enterobacteriaceae and Methicillin-Resistant Staphylococcus aureus in pig farms in Switzerland. The Science of the total environment, 603-604, pp. 401-405. Elsevier 10.1016/j.scitotenv.2017.06.110
Abraha, Million; Bertisch, Barbara; Hauser, Christoph; Klutschke, Michael; Egli-Gany, Dianne; Smid, Joost; Unemo, Magnus; Endimiani, Andrea; Donà, Valentina; Furrer, Hansjakob; Low, Nicola; Kasraian Fard, Sara (23 November 2017). Factors associated with anitmicrobial resistant gonorrheoea infections in men who have sex with men in Switzerland: case control study. In: Swiss Public Health Conference 2017. Congress Center Basel. 22 - 23 Nov 2017.
Ruppen, Corinne; Fröhlicher, Simone; Sendi, Parham (2017). Gentamicin susceptibility of 567 clinical group B streptococcal isolates. Journal of global antimicrobial resistance, 10, pp. 304-305. Elsevier 10.1016/j.jgar.2017.07.005
Donà, Valentina; Bernasconi, Odette Joëlle; Do Couto Pires, Joao Pedro; Collaud, Alexandra; Overesch, Gudrun; Ramette, Alban Nicolas; Perreten, Vincent; Endimiani, Andrea (2017). Heterogeneous Genetic Location of mcr-1 in Colistin-Resistant Escherichia coli Isolated from Humans and Retail Chicken Meat in Switzerland: Emergence of mcr-1-Carrying IncK2 Plasmids. Antimicrobial agents and chemotherapy, 61(11) American Society for Microbiology 10.1128/AAC.01245-17
Ruppen, Corinne; Rasmussen, Magnus; Casanova, Carlo; Sendi, Parham (2017). A 10-year observational study of Streptococcus dysgalactiae bacteraemia in adults: frequent occurrence among female intravenous drug users. Swiss medical weekly, 147(w14469), w14469. EMH Schweizerischer Ärzteverlag 10.4414/smw.2017.14469
Mika, Moana; Maurer, Josua; Korten, Insa Christina Severine; Allemann, Aurélie; Aebi, Suzanne; Brugger, Silvio D; Qi, Weihong; Frey, Urs; Latzin, Philipp; Hilty, Markus (2017). Influence of the pneumococcal conjugate vaccines on the temporal variation of pneumococcal carriage and the nasal microbiota in healthy infants: a longitudinal analysis of a case-control study. Microbiome, 5(1), p. 85. BioMed Central 10.1186/s40168-017-0302-6
Perny, Michael; Solyga, Magdalena; Grandgirard, Denis; Roccio, Marta; Leib, Stephen; Senn, Pascal (2017). Streptococcus pneumoniae-induced ototoxicity in organ of Corti explant cultures. Hearing research, 350, pp. 100-109. Elsevier 10.1016/j.heares.2017.04.012
Lora-Tamayo, Jaime; Senneville, Éric; Ribera, Alba; Bernard, Louis; Dupon, Michel; Zeller, Valérie; Li, Ho Kwong; Arvieux, Cédric; Clauss, Martin; Uçkay, Ilker; Vigante, Dace; Ferry, Tristan; Iribarren, José Antonio; Peel, Trisha N; Sendi, Parham; Miksic, Nina Gorišek; Rodríguez-Pardo, Dolors; Del Toro, María Dolores; Fernández-Sampedro, Marta; Dapunt, Ulrike; ... (2017). The Not-So-Good Prognosis of Streptococcal Periprosthetic Joint Infection Managed by Implant Retention: The Results of a Large Multicenter Study. Clinical infectious diseases, 64(12), pp. 1742-1752. Oxford University Press 10.1093/cid/cix227
Buschor, Stefanie; Cuenca Vera, Miguelangel; Uster, Stephanie Sarah; Schären, Olivier; Balmer, Maria L; Terrazos Miani, Miguel Angel; Schürch, Christian M; Hapfelmeier, Siegfried Hektor (2017). Innate immunity restricts Citrobacter rodentium A/E pathogenesis initiation to an early window of opportunity. PLoS pathogens, 13(6), e1006476. Public Library of Science 10.1371/journal.ppat.1006476
Schlapbach, Christoph; Sendi, Parham (2017). Serrated Marine Nose. New England journal of medicine NEJM, 376(3), p. 267. Massachusetts Medical Society MMS 10.1056/NEJMicm1604459
Jenkinson, Stephen P.; Grandgirard, Denis; Heidemann, Martina; Tscherter, Anne; Avondet, Marc-André; Leib, Stephen (2017). Embryonic Stem Cell-Derived Neurons Grown on Multi-Electrode Arrays as a Novel In vitro Bioassay for the Detection of Clostridium botulinum Neurotoxins. Frontiers in Pharmacology, 8(73) Frontiers 10.3389/fphar.2017.00073
Sendi, Parham; Hirzel, Cédric; Pfister, Stefan; Ackermann-Gäumann, Rahel; Grandgirard, Denis; Hewer, Ekkehard; Nirkko, Arto Christian (2017). Fatal Outcome of Tick-borne Encephalitis after Vaccine Failure. Frontiers in neurology, 8(119), p. 119. Frontiers Media S.A. 10.3389/fneur.2017.00119
Sendi, Parham; Borens, Olivier; Wahl, Peter; Clauss, Martin; Uçkay, Ilker (2017). Management of Asymptomatic Bacteriuria, Urinary Catheters and Symptomatic Urinary Tract Infections in Patients Undergoing Surgery for Joint Replacement: A Position Paper of the Expert Group 'Infection' of swissorthopaedics. Journal of bone and joint infection, 2(3), pp. 154-159. Ivyspring International Publisher 10.7150/jbji.20425
Oechslin, Corinne P.; Heutschi, Daniel; Lenz, Nicole; Tischhauser, Werner; Péter, Olivier; Rais, Olivier; Beuret, Christian M.; Leib, Stephen; Bankoul, Sergei; Ackermann-Gäumann, Rahel (2017). Prevalence of tick-borne pathogens in questing Ixodes ricinus ticks in urban and suburban areas of Switzerland. Parasites & Vectors, 10(1), p. 558. BioMed Central 10.1186/s13071-017-2500-2
Hotchen, Andrew J; McNally, Martin A; Sendi, Parham (2017). The Classification of Long Bone Osteomyelitis: A Systemic Review of the Literature. Journal of bone and joint infection, 2(4), pp. 167-174. Ivyspring International Publisher 10.7150/jbji.21050
Alexanian, Michael; Maric, Daniel; Jenkinson, Stephen Philip; Mina, Marco; Friedman, Clayton E.; Ting, Ching-Chia; Micheletti, Rudi; Plaisance, Isabelle; Nemir, Mohamed; Maison, Damien; Kernen, Jasmin; Pezzuto, Iole; Villeneuve, Dominic; Burdet, Frédéric; Ibberson, Mark; Leib, Stephen; Palpant, Nathan J.; Hernandez, Nouria; Ounzain, Samir and Pedrazzini, Thierry (2017). A transcribed enhancer dictates mesendoderm specification in pluripotency. Nature communications, 8(1), p. 1806. Nature Publishing Group 10.1038/s41467-017-01804-w
Agyeman, Philipp; Grandgirard, Denis; Leib, Stephen (2017). Neuroinflammation in Bacterial Meningitis. In: Lyck, R; Enzmann, G (eds.) The Blood Brain Barrier and Inflammation. Progress in Inflammation Research (pp. 213-252). Springer Nature 10.1007/978-3-319-45514-3_10
Jessen, Gerdhard L.; Lichtschlag, Anna; Ramette, Alban; Pantoja, Silvio; Rossel, Pamela E.; Schubert, Carsten J.; Struck, Ulrich; Boetius, Antje (2017). Hypoxia causes preservation of labile organic matter and changes seafloor microbial community composition (Black Sea). Science Advances, 3(2), e1601897. American Association for the Advancement of Science 10.1126/sciadv.1601897
Brugger, Silvio; Troxler, Lukas; Rüfenacht, Susanne; Frey, Pascal Marcel; Morand, Brigitte; Geyer, Rudolf; Mühlemann, Kathrin; Höck, Stefan; Thormann, Wolfgang; Furrer, Julien; Christen, Stephan; Hilty, Markus (2016). Polysaccharide capsule composition of pneumococcal serotype 19A subtypes: Unaltered among subtypes and independent of the nutritional environment. Infection and immunity, 84(11), pp. 3152-3160. American Society for Microbiology 10.1128/IAI.00474-16
Perny, Michael; Roccio, Marta; Grandgirard, Denis; Solyga, Magdalena; Senn, Pascal; Leib, Stephen (2016). The Severity of Infection Determines the Localization of Damage and Extent of Sensorineural Hearing Loss in Experimental Pneumococcal Meningitis. Journal of neuroscience, 36(29), pp. 7740-7749. Society for Neuroscience 10.1523/JNEUROSCI.0554-16.2016
Curiao, Tânia; Marchi, Emmanuela; Grandgirard, Denis; León-Sampedro, Ricardo; Viti, Carlo; Leib, Stephen; Baquero, Fernando; Oggioni, Marco R; Martinez, José Luis; Coque, Teresa M (2016). Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure. BMC Genomics, 17(491), p. 491. BioMed Central 10.1186/s12864-016-2778-z
Balmer, Maria Luisa; Ma, Eric H; Bantug, Glenn R; Grählert, Jasmin; Pfister, Simona; Glatter, Timo; Jauch, Annaïse; Dimeloe, Sarah; Slack, Emma; Dehio, Philippe; Krzyzaniak, Magdalena A; King, Carolyn G; Burgener, Anne-Valérie; Fischer, Marco; Develioglu, Leyla; Belle, Réka; Recher, Mike; Bonilla, Weldy V; Macpherson, Andrew; Hapfelmeier, Siegfried Hektor; ... (2016). Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function. Immunity, 44(6), pp. 1312-1324. Cell Press 10.1016/j.immuni.2016.03.016
van de Beek, D; Cabellos, C; Dzupova, O; Esposito, S; Klein, M; Kloek, A T; Leib, Stephen; Mourvillier, B; Ostergaard, C; Pagliano, P; Pfister, H W; Read, R C; Sipahi, O Resat; Brouwer, M C (2016). ESCMID guideline: diagnosis and treatment of acute bacterial meningitis. Clinical microbiology and infection, 22(Suppl 3), S37-S62. Blackwell Publishing 10.1016/j.cmi.2016.01.007
Gomez de Agüero Tamargo, Maria de la Mercedes; Ganal-Vonarburg, Stephanie C; Fuhrer, Tobias; Rupp, Sandra Carina; Uchimura, Yasuhiro; Li, Hai; Steinert, Anna; Heikenwalder, Mathias; Hapfelmeier, Siegfried Hektor; Sauer, Uwe; McCoy, Kathleen; Macpherson, Andrew (2016). The maternal microbiota drives early postnatal innate immune development. Science, 351(6279), pp. 1296-1302. American Association for the Advancement of Science 10.1126/science.aad2571
Fernández-López, David; Faustino, Joel; Klibanov, Alexander L; Derugin, Nikita; Blanchard, Elodie; Simon, Franziska; Leib, Stephen; Vexler, Zinaida S (2016). Microglial Cells Prevent Hemorrhage in Neonatal Focal Arterial Stroke. Journal of neuroscience, 36(10), pp. 2881-2893. Society for Neuroscience 10.1523/JNEUROSCI.0140-15.2016
Bürki, Sarah Elisabeth; Grandgirard, Denis; Datta, Alexandre N; Hackenberg, Annette; Martin, Florence; Schmitt-Mechelke, Thomas; Leib, Stephen L; Steinlin, Maja (2016). Inflammatory markers in pediatric stroke: An attempt to better understanding the pathophysiology. European journal of paediatric neurology, 20(2), pp. 252-260. Elsevier 10.1016/j.ejpn.2015.12.006
Bally, Lia; Grandgirard, Denis; Leib, Stephen (2016). Inhibition of Hippocampal Regeneration by Adjuvant Dexamethasone in Experimental Infant Rat Pneumococcal Meningitis. Antimicrobial agents and chemotherapy, 60(3), pp. 1841-1846. American Society for Microbiology 10.1128/AAC.02429-15
Hathaway, Lucy Jane; Grandgirard, Denis; Valente, Luca Gabriele; Täuber, Martin G.; Leib, Stephen (2016). Streptococcus pneumoniae capsule determines disease severity in experimental pneumococcal meningitis. Open Biology, 6(3) The Royal Society Publishing 10.1098/rsob.150269
Zürcher, Patrick; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Grossholz, Marius; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2016). A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model. BMC neurology, 16, p. 43. BioMed Central 10.1186/s12883-016-0565-8
Baumgartner, Denja; Aebi, Susanne; Grandgirard, Denis; Leib, Stephen; Draeger, Annette; Babiychuk, Eduard; Hathaway, Lucy Jane (2016). Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes. BMC microbiology, 16(1), p. 154. BioMed Central 10.1186/s12866-016-0777-5
Cuenca Vera, Miguelangel; Pfister, Simona; Buschor, Stefanie; Bayramova, Firuza; Hernandez, Sara B.; Cava, Felipe; Kuru, Erkin; Van Nieuwenhze, Michael S.; Brun, Yves V.; Matos Coelho, Fernanda; Hapfelmeier, Siegfried Hektor (2016). D-Alanine-Controlled Transient Intestinal Mono-Colonization with Non-Laboratory-Adapted Commensal E. coli Strain HS. PLoS ONE, 11(3), e0151872. Public Library of Science 10.1371/journal.pone.0151872
Moor, Kathrin; Wotzka, Sandra Y; Toska, Albulena; Diard, Médéric; Hapfelmeier, Siegfried Hektor; Slack, Emma (2016). Peracetic Acid Treatment Generates Potent Inactivated Oral Vaccines from a Broad Range of Culturable Bacterial Species. Frontiers in immunology, 7(34), p. 34. Frontiers Research Foundation 10.3389/fimmu.2016.00034
Studer, Nicolas; Desharnais, Lyne; Beutler, Markus; Brugiroux, Sandrine; Terrazos Miani, Miguel Angel; Menin, Laure; Schürch, Christian; McCoy, Kathy D.; Kuehne, Sarah A.; Minton, Nigel P.; Stecher, Bärbel; Bernier-Latmani, Rizlan; Hapfelmeier, Siegfried Hektor (2016). Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model. Frontiers in cellular and infection microbiology, 6(191), p. 191. Frontiers 10.3389/fcimb.2016.00191
Chevalier, Claire; Stojanović, Ozren; Colin, Didier J; Suarez-Zamorano, Nicolas; Tarallo, Valentina; Veyrat-Durebex, Christelle; Rigo, Dorothée; Fabbiano, Salvatore; Stevanović, Ana; Hagemann, Stefanie Claudia; Montet, Xavier; Seimbille, Yann; Zamboni, Nicola; Hapfelmeier, Siegfried Hektor; Trajkovski, Mirko (2015). Gut Microbiota Orchestrates Energy Homeostasis during Cold. Cell, 163(6), pp. 1360-1374. Cell Press 10.1016/j.cell.2015.11.004
Suárez-Zamorano, Nicolas; Fabbiano, Salvatore; Chevalier, Claire; Stojanović, Ozren; Colin, Didier J; Stevanović, Ana; Veyrat-Durebex, Christelle; Tarallo, Valentina; Rigo, Dorothée; Germain, Stéphane; Ilievska, Miroslava; Montet, Xavier; Seimbille, Yann; Hapfelmeier, Siegfried Hektor; Trajkovski, Mirko (2015). Microbiota depletion promotes browning of white adipose tissue and reduces obesity. Nature medicine, 21(12), pp. 1497-1501. Nature Publishing Group 10.1038/nm.3994
Frick, Tamara; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Hänggi, Matthias (2015). An improved simple rat model for global cerebral ischaemia by induced cardiac arrest. Neurological research, 38(4), pp. 373-380. Maney 10.1179/1743132815Y.0000000090
Liechti, Fabian D; Grandgirard, Denis; Leib, Stephen (2015). Bacterial meningitis: insights into pathogenesis and evaluation of new treatment options: a perspective from experimental studies. Future microbiology, 10(7), pp. 1195-1213. Future Medicine 10.2217/fmb.15.43
Liechti, F D; Grandgirard, Denis; Leib, Stephen (2015). The antidepressant fluoxetine protects the hippocampus from brain damage in experimental pneumococcal meningitis. Neuroscience, 297, pp. 89-94. Elsevier 10.1016/j.neuroscience.2015.03.056
Grandgirard, Denis; Furi, Leonardo; Ciusa, Maria Laura; Baldassarri, Lucilla; Knight, Daniel R; Morrissey, Ian; Largiadèr, Carlo Rodolfo; Leib, Stephen; Oggioni, Marco R (2015). Mutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression. BMC Genomics, 16(345), p. 345. BioMed Central 10.1186/s12864-015-1544-y
Wang, Junhua; Vuitton, Dominique A; Müller, Norbert; Hemphill, Andrew; Spiliotis, Markus; Blagosklonov, Oleg; Grandgirard, Denis; Leib, Stephen; Shalev, Itay; Levy, Gary; Lu, Xiaomei; Lin, Renyong; Wen, Hao; Gottstein, Bruno (2015). Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4+ CD25+ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice. PLoS neglected tropical diseases, 9(5), e0003755. Public Library of Science 10.1371/journal.pntd.0003755
Spaniol, Violeta; Bernhard, Sara; Aebi, Christoph (2015). Moraxella catarrhalis AcrAB-OprM efflux pump contributes to antimicrobial resistance and is enhanced during cold shock response. Antimicrobial agents and chemotherapy, 59(4), pp. 1886-1894. American Society for Microbiology 10.1128/AAC.03727-14
Bendel, Stepani; Springe, Dirk; Pereira, Adriano José; Grandgirard, Denis; Leib, Stephen; Putzu, Alessandro; Schlickeiser, Jannis; Jakob, Stephan M.; Takala, Jukka; Hänggi, Matthias (2015). Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? BMC anesthesiology, 15(2), p. 2. BioMed Central 10.1186/1471-2253-15-2
Liechti, Fabian D; Bächtold, Fabian; Grandgirard, Denis; Leppert, David; Leib, Stephen (2015). The matrix metalloproteinase inhibitor RS-130830 attenuates brain injury in experimental pneumococcal meningitis. Journal of neuroinflammation, 12(43), p. 43. BioMed Central 10.1186/s12974-015-0257-0
Pop Ristova, Petra; Wenzhöfer, Frank; Ramette, Alban; Felden, Janine; Boetius, Antje (2015). Spatial scales of bacterial community diversity at cold seeps (Eastern Mediterranean Sea). The ISME journal, 9(6), pp. 1306-1318. Nature Publishing Group 10.1038/ismej.2014.217
Ricci, Susanna; Grandgirard, Denis; Wenzel, Michael; Braccini, Tiziana; Salvatore, Paola; Oggioni, Marco R; Leib, Stephen; Koedel, Uwe (2014). Inhibition of matrix metalloproteinases attenuates brain damage in experimental meningococcal meningitis. BMC infectious diseases, 14(726), p. 726. BioMed Central 10.1186/s12879-014-0726-6
Hilty, Markus; Wüthrich, Daniel; Salter, Susannah J; Engel, Hans Jürg; Campbell, Samuel; Sá-Leão, Raquel; de Lencastre, Hermínia; Hermans, Peter; Sadowy, Ewa; Turner, Paul; Chewapreecha, Claire; Diggle, Mathew; Pluschke, Gerd; McGee, Lesley; Eser, Ozgen Köseoğlu; Low, Donald E; Smith-Vaughan, Heidi; Endimiani, Andrea; Küffer, Marianne; Dupasquier, Mélanie; ... (2014). Global phylogenomic analysis of nonencapsulated Streptococcus pneumoniae reveals a deep-branching classic lineage that is distinct from multiple sporadic lineages. Genome biology and evolution, 6(12), pp. 3281-3294. Oxford University Press 10.1093/gbe/evu263
Maffioli, Carola; Grandgirard, Denis; Engler, Olivier; Leib, Stephen (2014). A tick-borne encephalitis model in infant rats infected with langat virus. Journal of neuropathology and experimental neurology, 73(12), pp. 1107-1115. Lippincott Williams & Wilkins 10.1097/NEN.0000000000000131
Balmer, Maria L; Schürch, Christian; Saito, Yasuyuki; Geuking, Markus; Li, Hai; Cuenca, Miguelangel; Kovtonyuk, Larisa V; McCoy, Kathleen; Hapfelmeier, Siegfried; Ochsenbein, Adrian; Manz, Markus G; Slack, Emma; Macpherson, Andrew (2014). Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling. Journal of immunology, 193(10), pp. 5273-5283. American Association of Immunologists 10.4049/jimmunol.1400762
Coutinho, Leonam G; Christen, Stephan; Bellac, Caroline L; Fontes, Fabrícia; de Souza, Fladjule; Grandgirard, Denis; Leib, Stephen; Agnez-Lima, Lucymara F (2014). The kynurenine pathway is involved in bacterial meningitis. Journal of neuroinflammation, 11(169), p. 169. BioMed Central 10.1186/s12974-014-0169-4
Schaffner, Thierry Oliver; Hinds, Jason; Gould, Katherine A; Wüthrich, Daniel; Bruggmann, Rémy; Küffer, Marianne; Mühlemann, Kathrin; Hilty, Markus; Hathaway, Lucy Jane (2014). A point mutation in cpsE renders Streptococcus pneumoniae nonencapsulated and enhances its growth, adherence and competence. BMC microbiology, 14(210), p. 210. BioMed Central 10.1186/s12866-014-0210-x
Meichtry, Jurka; Born, Rita; Küffer, Marianne; Zwahlen, Marcel; Albrich, Werner C.; Brugger, Silvio; Mühlemann, Kathrin; Hilty, Markus (2014). Serotype epidemiology of invasive pneumococcal disease in Swiss adults: A nationwide population-based study. Vaccine, 32(40), pp. 5185-5191. Elsevier 10.1016/j.vaccine.2014.07.060
Balmer, Maria Luisa; Slack, Emma; De Gottardi, Andrea; Lawson, Melissa; Hapfelmeier, Siegfried Hektor; Miele, Luca; Grieco, Antonio; Van Vlierberghe, Hans; Fahrner, René; Patuto, Nicola; Bernsmeier, Christine; Ronchi, Francesca; Wyss, Madeleine; Keogh-Stroka, Deborah M.; Dickgreber, Nina; Heim, Markus H; McCoy, Kathy D; Macpherson, Andrew (2014). The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota. Science translational medicine, 6(237), 237ra66. American Association for the Advancement of Science 10.1126/scitranslmed.3008618
Agyeman, Philipp; Grandgirard, Denis; Leib, Stephen (2014). Pathogenesis and Pathophysiology of Bacterial Infections. In: Scheld, Michael; Whitley, Richard J.; Marra, Christina M. (eds.) Infections of the Central Nervous System (pp. 341-364). Philadelphia, PA, USA: Lippincott Williams & Wilkins
Engel, Hans Jürg; Mika, Moana; Denapaite, Dalia; Hakenbeck, Regine; Mühlemann, Kathrin; Heller, Manfred; Hathaway, Lucy Jane; Hilty, Markus (2014). A low affinity penicillin-binding protein 2x is required for heteroresistance in Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 58(7), pp. 3934-3941. American Society for Microbiology 10.1128/AAC.02547-14
Liechti, Fabian D; Grandgirard, Denis; Leppert, David; Leib, Stephen (2014). Matrix metalloproteinase inhibition lowers mortality and brain injury in experimental pneumococcal meningitis. Infection and immunity, 82(4), pp. 1710-1718. American Society for Microbiology 10.1128/IAI.00073-14
Hirt-Minkowski, Patricia; Marti, Hans-Peter; Hönger, Gideon; Grandgirard, Denis; Leib, Stephen; Amico, Patrizia; Schaub, Stefan (2014). Correlation of serum and urinary matrix metalloproteases/tissue inhibitors of metalloproteases with subclinical allograft fibrosis in renal transplantation. Transplant immunology, 30(1), pp. 1-6. Elsevier 10.1016/j.trim.2013.11.004
Holler, Jon G.; Brandt, Christian T.; Leib, Stephen L.; Rowland, Ian J.; Ostergaard, Christian (2014). Increase in hippocampal water diffusion and volume during experimental pneumococcal meningitis is aggravated by bacteremia. BMC infectious diseases, 14(1), p. 240. BioMed Central 10.1186/1471-2334-14-240
Liechti, Fabian D; Stüdle, Nicolas; Theurillat, Regula; Grandgirard, Denis; Thormann, Wolfgang; Leib, Stephen (2014). The mood-stabilizer lithium prevents hippocampal apoptosis and improves spatial memory in experimental meningitis. PLoS ONE, 9(11), e113607. Public Library of Science 10.1371/journal.pone.0113607
Baranger, Kévin; Rivera, Santiago; Liechti, Fabian D; Grandgirard, Denis; Bigas, Judit; Seco, Jesús; Tarrago, Teresa; Leib, Stephen; Khrestchatisky, Michel (2014). Endogenous and synthetic MMP inhibitors in CNS physiopathology. In: Dityatev, Alexander; Wehrle-Haller, Bernhard; Pitkänen, Asla (eds.) Brain Extracellular Matrix in Health and Disease. Progress in Brain Research: Vol. 214 (pp. 313-351). Elsevier 10.1016/B978-0-444-63486-3.00014-1
Coutinho, Leonam G; Grandgirard, Denis; Leib, Stephen L.; Agnez-Lima, Lucymara F (2013). Cerebrospinal-fluid cytokine and chemokine profile in patients with pneumococcal and meningococcal meningitis. BMC infectious diseases, 13(1), p. 326. BioMed Central 10.1186/1471-2334-13-326
Spaniol, Violeta; Wyder, Stefan; Aebi, Christoph (2013). RNA-Seq-based analysis of the physiologic cold shock-induced changes in Moraxella catarrhalis gene expression. PLoS ONE, 8(7), e68298. Public Library of Science 10.1371/journal.pone.0068298
Monney, Thierry; Grandgirard, Denis; Leib, Stephen; Hemphill, Andrew (2013). Use of a Th1 Stimulator Adjuvant for Vaccination against Neospora caninum Infection in the Pregnant Mouse Model. Pathogens, 2(2), pp. 193-208. MDPI AG 10.3390/pathogens2020193
Grandgirard, Denis; Gäumann, Rahel; Coulibaly, Boubacar; Dangy, Jean-Pierre; Sie, Ali; Junghanss, Thomas; Schudel, Hans; Pluschke, Gerd; Leib, Stephen L. (2013). The causative pathogen determines the inflammatory profile in cerebrospinal fluid and outcome in patients with bacterial meningitis. Mediators of inflammation, 2013, p. 312476. Hindawi Publishing Corp. 10.1155/2013/312476
Fritz, Jörg H; Rojas, Olga Lucia; Simard, Nathalie; McCarthy, Douglas D; Hapfelmeier, Siegfried; Rubino, Stephen; Robertson, Susan J; Larijani, Mani; Gosselin, Jean; Ivanov, Ivaylo I; Martin, Alberto; Casellas, Rafael; Philpott, Dana J; Girardin, Stephen E; McCoy, Kathy D; Macpherson, Andrew J; Paige, Christopher J; Gommerman, Jennifer L (2012). Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut. Nature, 481(7380), pp. 199-203. London: Macmillan Journals Ltd. 10.1038/nature10698
Slack, Emma; Balmer, Maria Luisa; Fritz, Jörg H; Hapfelmeier, Siegfried (2012). Functional flexibility of intestinal IgA - broadening the fine line. Frontiers in immunology, 3, p. 100. Lausanne: Frontiers Research Foundation 10.3389/fimmu.2012.00100
Macpherson, Andrew J; Geuking, Markus B; Slack, Emma; Hapfelmeier, Siegfried; McCoy, Kathy D (2012). The habitat, double life, citizenship, and forgetfulness of IgA. Immunological reviews, 245(1), pp. 132-146. Oxford: Wiley-Blackwell 10.1111/j.1600-065X.2011.01072.x
Lüer, Sonja; Troller, Rolf; Jetter, Marion; Spaniol, Violeta; Aebi, Christoph (2011). Topical curcumin can inhibit deleterious effects of upper respiratory tract bacteria on human oropharyngeal cells in vitro: potential role for patients with cancer therapy induced mucositis? Supportive care in cancer, 19(6), pp. 799-806. Berlin: Springer-Verlag 10.1007/s00520-010-0894-x
Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007
Geuking, Markus B; Cahenzli, Julia; Lawson, Melissa A E; Ng, Derek C K; Slack, Emma; Hapfelmeier, Siegfried; McCoy, Kathy D; Macpherson, Andrew J (2011). Intestinal bacterial colonization induces mutualistic regulatory T cell responses. Immunity, 34(5), pp. 794-806. Cambridge, Mass.: Cell Press 10.1016/j.immuni.2011.03.021
Woehrl, Bianca; Klein, Matthias; Grandgirard, Denis; Koedel, Uwe; Leib, Stephen (2011). Bacterial meningitis: current therapy and possible future treatment options. Expert review of anti-infective therapy, 9(11), pp. 1053-1065. London: Expert Reviews 10.1586/ERI.11.129
Hofer, Sandra; Grandgirard, Denis; Burri, Denise; Fröhlich, Tanja K.; Leib, Stephen L. (2011). Bacterial meningitis impairs hippocampal neurogenesis. Journal of neuropathology and experimental neurology, 70(10), pp. 890-899. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/NEN.0b013e3182303f31
Monney, Thierry; Rütti, David; Schorer, Michelle; Debache, Karim; Grandgirard, Denis; Leib, Stephen L.; Hemphill, Andrew (2011). RecNcMIC3-1-R is a microneme- and rhoptry-based chimeric antigen that protects against acute neosporosis and limits cerebral parasite load in the mouse model for Neospora caninum infection. Vaccine, 29(40), pp. 6967-6975. Amsterdam: Elsevier 10.1016/j.vaccine.2011.07.038
Blaser, Cornelia; Wittwer, Matthias; Grandgirard, Denis; Leib, Stephen L. (2011). Adjunctive dexamethasone affects the expression of genes related to inflammation, neurogenesis and apoptosis in infant rat pneumococcal meningitis. PLoS ONE, 6(3), e17840. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0017840
Margos, M.C.; Grandgirard, Denis; Leib, Stephen; Gottstein, Bruno (2011). In vitro induction of lymph node cell proliferation by mouse bone marrow dendritic cells following stimulation with different Echinococcus multilocularis antigens. Journal of helminthology, 85(2), pp. 128-137. Cambridge: Cambridge University Press 10.1017/S0022149X10000878
Spaniol, Violeta; Troller, Rolf; Schaller, André; Aebi, Christoph (2011). Physiologic cold shock of Moraxella catarrhalis affects the expression of genes involved in the iron acquisition, serum resistance and immune evasion. BMC microbiology, 11, p. 182. London: BioMed Central 10.1186/1471-2180-11-182
Barbier, François; Lebeaux, David; Hernandez, David; Delannoy, Anne-Sophie; Caro, Valérie; François, Patrice; Schrenzel, Jacques; Ruppé, Etienne; Gaillard, Kevin; Wolff, Michel; Brisse, Sylvain; Andremont, Antoine; Ruimy, Raymond (2011). High prevalence of the arginine catabolic mobile element in carriage isolates of methicillin-resistant Staphylococcus epidermidis. Journal of antimicrobial chemotherapy, 66(1), pp. 29-36. Oxford University Press 10.1093/jac/dkq410
Mégevand, C; Gervaix, A; Heininger, U; Berger, C; Aebi, C; Vaudaux, B; Kind, C; Gnehm, H-P; Hitzler, M; Renzi, G; Schrenzel, J; François, P (2010). Molecular epidemiology of the nasal colonization by methicillin-susceptible Staphylococcus aureus in Swiss children. Clinical microbiology and infection, 16(9), pp. 1414-20. Oxford: Blackwell Publishing 10.1111/j.1469-0691.2009.03090.x
Hapfelmeier, Siegfried; Macpherson, Andrew J. (2010). In remembrance of commensal intestinal microbes. Communicative & integrative biology, 3(6), pp. 569-571. Austin, Tex.: Landes Bioscience 10.4161/cib.3.6.13011
Jetter, Marion; Spaniol, Violeta; Troller, Rolf; Aebi, Christoph (2010). Down-regulation of porin M35 in Moraxella catarrhalis by aminopenicillins and environmental factors and its potential contribution to the mechanism of resistance to aminopenicillins. Journal of antimicrobial chemotherapy, 65(10), pp. 2089-96. Oxford: Oxford University Press 10.1093/jac/dkq312
Grandgirard, Denis; Leib, Stephen L. (2010). Meningitis in neonates: bench to bedside. Clinics in perinatology, 37(3), pp. 655-676. New York, N.Y.: Elsevier 10.1016/j.clp.2010.05.004
Wittwer, Matthias; Grandgirard, Denis; Rohrbach, Janine; Leib, Stephen L. (2010). Tracking the transcriptional host response from the acute to the regenerative phase of experimental pneumococcal meningitis. BMC infectious diseases, 10(176), p. 176. London: BioMed Central 10.1186/1471-2334-10-176
Blaser, Cornelia; Klein, Matthias; Grandgirard, Denis; Wittwer, Matthias; Peltola, Heikki; Weigand, Michael; Koedel, Uwe; Leib, Stephen L. (2010). Adjuvant glycerol is not beneficial in experimental pneumococcal meningitis. BMC infectious diseases, 10(84), p. 84. London: BioMed Central 10.1186/1471-2334-10-84
Grandgirard, Denis; Oberson, Kevin; Bühlmann, Angela; Gäumann, Rahel; Leib, Stephen L. (2010). Attenuation of cerebrospinal fluid inflammation by the nonbacteriolytic antibiotic daptomycin versus that by ceftriaxone in experimental pneumococcal meningitis. Antimicrobial agents and chemotherapy, 54(3), pp. 1323-1326. Washington, D.C.: American Society for Microbiology 10.1128/AAC.00812-09
Slack, Emma; Hapfelmeier, Siegfried; Stecher, Bärbel; Velykoredko, Yuliya; Stoel, Maaike; Lawson, Melissa A E; Geuking, Markus B; Beutler, Bruce; Tedder, Thomas F; Hardt, Wolf-Dietrich; Bercik, Premysl; Verdu, Elena F; McCoy, Kathy D; Macpherson, Andrew J (2009). Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. Science, 325(5940), pp. 617-620. Washington, D.C.: American Association for the Advancement of Science 10.1126/science.1172747
Spaniol, Violeta; Heiniger, Nadja; Troller, Rolf; Aebi, Christoph (2008). Outer membrane protein UspA1 and lipooligosaccharide are involved in invasion of human epithelial cells by Moraxella catarrhalis. Microbes and infection, 10(1), pp. 3-11. Paris: Elsevier Masson SAS 10.1016/j.micinf.2007.09.014
Gehre, F.; Leib, Stephen L.; Grandgirard, Denis; Kummer, Jürg; Bühlmann, Angela; Simon, Franziska; Gäumann, R.; Kharat, A. S.; Täuber, Martin G.; Tomasz, A. (2008). Essential role of choline for pneumococcal virulence in an experimental model of meningitis. Internal medicine journal, 264(2), pp. 143-154. Sydney: Blackwell 10.1111/j.1365-2796.2008.01930.x
Sury, Matthias D.; Agarinis, Claudia; Widmer, Hans-Rudolf; Leib, Stephen L.; Christen, Stephan (2008). JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 32(1), pp. 142-150. Amsterdam: Elsevier 10.1016/J.nbd.2008.07.006
Sellner, Johann; Greeve, Isabell; Findling, Oliver; Kamm, Christian P.; Minten, Carsten; Engelhardt, Britta; Grandgirard, Denis; Leib, Stephen L.; Mattle, Heinrich P (2008). Effect of interferon-beta and atorvastatin on Th1/Th2 cytokines in multiple sclerosis. Neurochemistry international, 53(1-2), pp. 17-21. Amsterdam: Elsevier 10.1016/j.neuint.2008.04.004
Grandgirard, Denis; Loeffler, Jutta M.; Fischetti, Vincent A.; Leib, Stephen L. (2008). Phage lytic enzyme Cpl-1 for antibacterial therapy in experimental pneumococcal meningitis. Journal of infectious diseases, 197(11), pp. 1519-1522. Cary, N.C.: The University of Chicago Press 10.1086/587942
Sellner, Johann; Greeve, I; Findling, O; Grandgirard, Denis; Leib, Stephen L.; Mattle, H P (2008). Atorvastatin does not alter serum levels of sCD95 and sCD95L in multiple sclerosis. Clinical and experimental immunology, 152(2), pp. 280-284. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2249.2008.03630.x
Hapfelmeier, Siegfried; Müller, Andreas J; Stecher, Bärbel; Kaiser, Patrick; Barthel, Manja; Endt, Kathrin; Eberhard, Matthias; Robbiani, Riccardo; Jacobi, Christoph A; Heikenwalder, Mathias; Kirschning, Carsten; Jung, Steffen; Stallmach, Thomas; Kremer, Marcus; Hardt, Wolf-Dietrich (2008). Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitis. The Journal of experimental medicine, 205(2), pp. 437-450. Rockefeller Univ. Press 10.1084/jem.20070633
Macpherson, Andrew J; Hapfelmeier, Siegfried; McCoy, Kathy D (2007). The armed truce between the intestinal microflora and host mucosal immunity. Seminars in immunology, 19(2), pp. 57-58. W.B. Saunders 10.1016/j.smim.2007.04.001
Suar, Mrutyunjay; Jantsch, Jonathan; Hapfelmeier, Siegfried; Kremer, Marcus; Stallmach, Thomas; Barrow, Paul A; Hardt, Wolf-Dietrich (2006). Virulence of broad- and narrow-host-range Salmonella enterica serovars in the streptomycin-pretreated mouse model. Infection and immunity, 74(1), pp. 632-644. American Society for Microbiology 10.1128/IAI.74.1.632-644.2006
Rhême, Céline; Ehrengruber, Markus U; Grandgirard, Denis (2005). Alphaviral cytotoxicity and its implication in vector development. Experimental physiology, 90(1), pp. 45-52. Blackwell 10.1113/expphysiol.2004.028142
Bifrare, Yoeng-Delphine; Kummer, Jürg; Joss, Philipp; Täuber, Martin G.; Leib, Stephen (2005). Brain-derived neurotrophic factor protects against multiple forms of brain injury in bacterial meningitis. Journal of infectious diseases, 191(1), pp. 40-45. The University of Chicago Press 10.1086/426399
Hapfelmeier, Siegfried; Hardt, Wolf-Dietrich (2005). A mouse model for S. typhimurium-induced enterocolitis. Trends in microbiology, 13(10), pp. 497-503. Elsevier Current Trends 10.1016/j.tim.2005.08.008
Stecher, Bärbel; Macpherson, Andrew J; Hapfelmeier, Siegfried; Kremer, Marcus; Stallmach, Thomas; Hardt, Wolf-Dietrich (2005). Comparison of Salmonella enterica serovar Typhimurium colitis in germfree mice and mice pretreated with streptomycin. Infection and immunity, 73(6), pp. 3228-3241. American Society for Microbiology 10.1128/IAI.73.6.3228-3241.2005
Hapfelmeier, Siegfried; Stecher, Bärbel; Barthel, Manja; Kremer, Marcus; Müller, Andreas J; Heikenwalder, Mathias; Stallmach, Thomas; Hensel, Michael; Pfeffer, Klaus; Akira, Shizuo; Hardt, Wolf-Dietrich (2005). The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms. Journal of immunology, 174(3), pp. 1675-1685. American Association of Immunologists
Gianinazzi, Christian; Grandgirard, Denis; Simon, Franziska; Imboden, Hans; Joss, Philipp; Täuber, Martin G.; Leib, Stephen (2004). Apoptosis of hippocampal neurons in organotypic slice culture models: direct effect of bacteria revisited. Journal of neuropathology and experimental neurology, 63(6), pp. 610-617. Lippincott Williams & Wilkins
Stecher, Bärbel; Hapfelmeier, Siegfried; Müller, Catherine; Kremer, Marcus; Stallmach, Thomas; Hardt, Wolf-Dietrich (2004). Flagella and chemotaxis are required for efficient induction of Salmonella enterica serovar Typhimurium colitis in streptomycin-pretreated mice. Infection and immunity, 72(7), pp. 4138-4150. American Society for Microbiology 10.1128/IAI.72.7.4138-4150.2004
Ehrbar, Kristin; Hapfelmeier, Siegfried; Stecher, Bärbel; Hardt, Wolf-Dietrich (2004). InvB is required for type III-dependent secretion of SopA in Salmonella enterica serovar Typhimurium. Journal of bacteriology, 186(4), pp. 1215-1219. American Society for Microbiology 10.1128/JB.186.4.1215-1219.2004
Hapfelmeier, Siegfried; Ehrbar, Kristin; Stecher, Bärbel; Barthel, Manja; Kremer, Marcus; Hardt, Wolf-Dietrich (2004). Role of the Salmonella pathogenicity island 1 effector proteins SipA, SopB, SopE, and SopE2 in Salmonella enterica subspecies 1 serovar Typhimurium colitis in streptomycin-pretreated mice. Infection and immunity, 72(2), pp. 795-809. American Society for Microbiology 10.1128/IAI.72.2.795-809.2004
Gianinazzi, Christian; Grandgirard, Denis; Imboden, Hans; Egger, Lotti; Meli, Damian N; Bifrare, Yoeng-Delphine; Joss, Philipp; Täuber, Martin G.; Borner, Christoph; Leib, Stephen (2003). Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis. Acta neuropathologica, 105(5), pp. 499-507. Springer 10.1007/s00401-003-0672-7
Barthel, Manja; Hapfelmeier, Siegfried; Quintanilla-Martínez, Leticia; Kremer, Marcus; Rohde, Manfred; Hogardt, Michael; Pfeffer, Klaus; Rüssmann, Holger; Hardt, Wolf-Dietrich (2003). Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host. Infection and immunity, 71(5), pp. 2839-2858. American Society for Microbiology 10.1128/IAI.71.5.2839-2858.2003
Baron, C; Domke, N; Beinhofer, M; Hapfelmeier, Siegfried (2001). Elevated temperature differentially affects virulence, VirB protein accumulation, and T-pilus formation in different Agrobacterium tumefaciens and Agrobacterium vitis strains. Journal of bacteriology, 183(23), pp. 6852-6861. American Society for Microbiology 10.1128/JB.183.23.6852-6861.2001
Hapfelmeier, Siegfried; Domke, N; Zambryski, P C; Baron, C (2000). VirB6 is required for stabilization of VirB5 and VirB3 and formation of VirB7 homodimers in Agrobacterium tumefaciens. Journal of bacteriology, 182(16), pp. 4505-4511. American Society for Microbiology 10.1128/JB.182.16.4505-4511.2000
Grandgirard, Denis; Studer, Erwin; Monney, Laurent; Belser, Tanja; Fellay, Isabelle; Borner, Christoph; Michel, Marcel R. (1998). Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2. EMBO journal, 17(5), pp. 1268-1278. Nature Publishing Group 10.1093/emboj/17.5.1268
Leib, Stephen (1994). [A case from practice (305). Recurrent erysipelas--tinea pedis et unginum--chronic venous insufficiency]. Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis, 83(39), pp. 1089-1090.
Schittny, Johannes C.; Timpl, Rupert; Engel, Jürgen (1988). High resolution immunoelectron microscopic localization of functional domains of laminin, nidogen, and heparan sulfate proteoglycan in epithelial basement membrane of mouse cornea reveals different topological orientations. Journal of cell biology, 107(4), pp. 1599-1610. Rockefeller Institute Press
Preiswerk, Benjamin; Imkamp, Frank; Vorburger, Denise; Hömke, Rico V.; Keller, Peter M.; Wagner, Karoline (2020). Mycoplasma penetrans bacteremia in an immunocompromised patient detected by metagenomic sequencing: a case report. BMC infectious diseases, 20(1), p. 7. BioMed Central 10.1186/s12879-019-4723-7
