Aldeia, Claudia; Campos-Madueno, Edgar I; Endimiani, Andrea (2024). Genomic insights into Leminorella grimontii and its chromosomal class A GRI β-lactamase. European journal of clinical microbiology & infectious diseases, 43(9), pp. 1855-1860. Springer 10.1007/s10096-024-04888-7
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Leminorella grimontii strain LG-KP-E1-2-T0 was isolated from Zophobas morio larvae. It showed a susceptibility phenotype compatible with the expression of an inducible extended-spectrum β-lactamase. The presence of a chromosomal bla gene encoding for the class A GRI-1 β-lactamase was revealed by whole-genome sequencing. GRI-1 shared the highest amino acid identity with RIC-1 and OXY-type β-lactamases (76-80%). Analysis of six further publicly-available L. grimontii draft genomes deposited in NCBI revealed that blaGRI-1 was always present. Core-genome analysis indicated that LG-KP-E1-2-T0 was unique from other strains. We provided the first complete genome of L. grimontii and new insights on its chromosomal β-lactamases.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases |
Graduate School: |
Graduate School for Cellular and Biomedical Sciences (GCB) |
UniBE Contributor: |
Azevedo da Aldeia, Claudia Cristina, Campos-Madueno, Edgar Igor, Endimiani, Andrea |
Subjects: |
600 Technology > 610 Medicine & health 500 Science > 570 Life sciences; biology |
ISSN: |
0934-9723 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
04 Jul 2024 09:29 |
Last Modified: |
28 Aug 2024 00:14 |
Publisher DOI: |
10.1007/s10096-024-04888-7 |
PubMed ID: |
38958811 |
Uncontrolled Keywords: |
Leminorella Zophobas ESBL GRI-1 Genome Sequencing β-lactamases |
BORIS DOI: |
10.48350/198483 |
URI: |
https://boris.unibe.ch/id/eprint/198483 |
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