Williams, Hannah L.; Frei, Ana Leni; Koessler, Thibaud; Berger, Martin D.; Dawson, Heather; Michielin, Olivier; Zlobec, Inti (2024). The current landscape of spatial biomarkers for prediction of response to immune checkpoint inhibition. NPJ precision oncology, 8(1), p. 178. Springer Nature 10.1038/s41698-024-00671-1
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Enabling the examination of cell-cell relationships in tissue, spatially resolved omics technologies have revolutionised our perspectives on cancer biology. Clinically, the development of immune checkpoint inhibitors (ICI) has advanced cancer therapeutics. However, a major challenge of effective implementation is the identification of predictive biomarkers of response. In this review we examine the potential added predictive value of spatial biomarkers of response to ICI beyond current clinical benchmarks.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology > Clinical Pathology 04 Faculty of Medicine > Service Sector > Institute of Pathology 04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology |
Graduate School: |
Graduate School for Cellular and Biomedical Sciences (GCB) |
UniBE Contributor: |
Williams, Hannah Louise, Frei, Ana Leni, Berger, Martin Dave, Dawson, Heather, Zlobec, Inti |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
2397-768X |
Publisher: |
Springer Nature |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
14 Aug 2024 09:18 |
Last Modified: |
14 Aug 2024 09:26 |
Publisher DOI: |
10.1038/s41698-024-00671-1 |
PubMed ID: |
39138341 |
BORIS DOI: |
10.48350/199684 |
URI: |
https://boris.unibe.ch/id/eprint/199684 |
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