Gottstein, Bruno; Wittwer, Matthias; Schild, Marc; Merli, Michael; Leib, Stephen L.; Müller, Norbert; Müller, Joachim; Jaggi, Rolf (2010). Hepatic gene expression profile in mice perorally infected with Echinococcus multilocularis eggs. PLoS ONE, 5(4), e9779. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0009779
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Alveolar echinococcosis (AE) is a severe chronic hepatic parasitic disease currently emerging in central and eastern Europe. Untreated AE presents a high mortality (>90%) due to a severe hepatic destruction as a result of parasitic metacestode proliferation which behaves like a malignant tumor. Despite this severe course and outcome of disease, the genetic program that regulates the host response leading to organ damage as a consequence of hepatic alveolar echinococcosis is largely unknown.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Parasitology 04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Pathologie > Forschungsgruppe Molekularbiologie |
UniBE Contributor: |
Gottstein, Bruno, Leib, Stephen, Müller, Norbert, Müller, Heinz Joachim, Jaggi, Rolf |
Subjects: |
600 Technology > 630 Agriculture |
ISSN: |
1932-6203 |
Publisher: |
Public Library of Science |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:07 |
Last Modified: |
05 Dec 2022 14:00 |
Publisher DOI: |
10.1371/journal.pone.0009779 |
PubMed ID: |
20368974 |
Web of Science ID: |
000276418200003 |
BORIS DOI: |
10.7892/boris.287 |
URI: |
https://boris.unibe.ch/id/eprint/287 (FactScience: 197363) |
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