High Prevalence of Extended-Spectrum β-Lactamase, Plasmid-Mediated AmpC and Carbapenemase genes in Food for Pets

Seiffert, Salome Nadja; Carattoli, Alessandra; Tinguely, Regula; Lupo, Agnese; Perreten, Vincent; Endimiani, Andrea (2014). High Prevalence of Extended-Spectrum β-Lactamase, Plasmid-Mediated AmpC and Carbapenemase genes in Food for Pets. Antimicrobial agents and chemotherapy, 58(10), pp. 6320-6323. American Society for Microbiology 10.1128/AAC.03185-14

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We evaluated the pet food contained in thirty packages as potential origin of extended-spectrum cephalosporin-resistant Gram-negative organisms and β-lactamase genes (bla). Alive bacteria were not detected by selective culture. However, PCR investigations on food DNA extracts indicated that samples harbored blaCTX-M-15 (53.3%), blaCMY-4 (20%), and blaVEB-4-like (6.7%). Particularly worrisome was the presence of blaOXA-48-like carbapenemases (13.3%). Original pet food ingredients and/or the production process were highly contaminated with bacteria carrying clinically relevant acquired bla genes.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > General Bacteriology

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Seiffert, Salome Nadja; Carattoli, Alessandra; Tinguely, Regula; Lupo, Agnese; Perreten, Vincent and Endimiani, Andrea

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 590 Animals (Zoology)
600 Technology > 610 Medicine & health

ISSN:

0066-4804

Publisher:

American Society for Microbiology

Funders:

[112] St. Hilda's College, Oxford
[UNSPECIFIED] Internal funds of IFIK

Language:

English

Submitter:

Andrea Endimiani

Date Deposited:

22 May 2015 15:44

Last Modified:

22 May 2015 15:44

Publisher DOI:

10.1128/AAC.03185-14

PubMed ID:

25092703

BORIS DOI:

10.7892/boris.69113

URI:

https://boris.unibe.ch/id/eprint/69113

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