The alphavbeta6 integrin is a highly specific immunohistochemical marker for cholangiocarcinoma

Patsenker, E; Wilkens, L; Banz, V; Osterreicher, C H; Weimann, R; Eisele, S; Keogh, A; Stroka, D; Zimmermann, A; Stickel, F (2010). The alphavbeta6 integrin is a highly specific immunohistochemical marker for cholangiocarcinoma. Journal of hepatology, 52(3), pp. 362-9. Amsterdam: Elsevier 10.1016/j.jhep.2009.12.006

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Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are common primary hepatic malignancies. Their immunohistological differentiation using specific markers is pivotal for treatment and prognosis. We found alphavbeta6 integrin strongly upregulated in biliary fibrosis, but its expression in primary and secondary liver tumours is unknown. Here, we aimed to evaluate the diagnostic applicability of alphavbeta6 integrin in differentiating primary liver cancers.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

Weimann, Rosemarie; Keogh-Stroka, Deborah M.; Zimmermann, Arthur and Stickel, Felix

ISSN:

0168-8278

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:08

Last Modified:

04 May 2014 23:04

Publisher DOI:

10.1016/j.jhep.2009.12.006

PubMed ID:

20137822

Web of Science ID:

000276577900009

URI:

https://boris.unibe.ch/id/eprint/705 (FactScience: 200421)

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