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Spari, Daniel; Schmid, Annina; Sanchez-Taltavull, Daniel; Murugan, Shaira; Keller, Keely; Ennaciri, Nadia; Salm, Lilian; Stroka, Deborah; Beldi, Guido (2024). Released bacterial ATP shapes local and systemic inflammation during abdominal sepsis. eLife, 13 eLife Sciences Publications 10.7554/eLife.96678
Zhang, Ting; Ambrodji, Alisa; Huang, Huixing; Bouchonville, Kelly J; Etheridge, Amy S; Schmidt, Remington E; Bembenek, Brianna M; Temesgen, Zoey B; Wang, Zhiquan; Innocenti, Federico; Stroka, Deborah; Diasio, Robert B; Largiadèr, Carlo R; Offer, Steven M (2024). Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD). eLife, 13 eLife Sciences Publications 10.7554/eLife.94075
Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Esposito, Roberta; Lanzos, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 5463. Nature Publishing Group 10.1038/s41467-023-41288-5
Magyar, Christian Tibor Josef; Vashist, Yogesh K; Stroka, Deborah; Kim-Fuchs, Corina; Berger, Martin D; Banz, Vanessa M (2023). Heat shock protein 90 (HSP90) inhibitors in gastrointestinal cancer: where do we currently stand?-A systematic review. Journal of cancer research and clinical oncology, 149(10), pp. 8039-8050. Springer 10.1007/s00432-023-04689-z
Esposito, Roberta; Lanzós, Andrés; Uroda, Tina; Ramnarayanan, Sunandini; Büchi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Lia, Mela; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matúš; Basile, Giulia; Meise, Dominik F; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; ... (2023). Tumour mutations in long noncoding RNAs enhance cell fitness. Nature communications, 14(1), p. 3342. Nature Publishing Group 10.1038/s41467-023-39160-7
Koch, Jonas P; Roth, Selina M; Quintin, Aurélie; Gavini, Jacopo; Orlando, Eleonora; Riedo, Rahel; Pozzato, Chiara; Hayrapetyan, Liana; Aebersold, Ruedi; Stroka, Deborah M; Aebersold, Daniel M; Medo, Matúš; Zimmer, Yitzhak; Medova, Michaela (2023). A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response. Oncogene, 42(26), pp. 2113-2125. Nature Publishing Group 10.1038/s41388-023-02714-6
Ontsouka, Edgar; Schroeder, Mariana; Ok, Linda; Vaillancourt, Cathy; Stroka, Deborah; Albrecht, Christiane (2023). The Placenta-A New Source of Bile Acids during Healthy Pregnancy? First Results of a Gene Expression Study in Humans and Mice. International journal of molecular sciences, 24(11) MDPI 10.3390/ijms24119511
Jakob, Manuel O; Spari, Daniel; Sánchez Taltavull, Daniel; Salm, Lilian; Yilmaz, Bahtiyar; Doucet Ladevèze, Rémi; Mooser, Catherine; Pereyra, David; Ouyang, Ye; Schmidt, Theresa; Mattiola, Irene; Starlinger, Patrick; Stroka, Deborah; Tschan, Franziska; Candinas, Daniel; Gasteiger, Georg; Klose, Christoph S N; Diefenbach, Andreas; Gomez de Agüero, Mercedes and Beldi, Guido (2023). ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery. Cell reports, 42(3), p. 112269. Cell Press 10.1016/j.celrep.2023.112269
Birrer, Fabienne; Brodie, Tess; Stroka, Deborah (2023). OMIP-088: Twenty-target imaging mass cytometry panel for major cell populations in mouse formalin fixed paraffin embedded liver. Cytometry Part A, 103(3), pp. 189-192. Wiley 10.1002/cyto.a.24714
Lett, Martin J; Mehta, Hema; Keogh, Adrian; Jaeger, Tina; Jacquet, Maxime; Powell, Kate; Meier, Marie-Anne; Fofana, Isabel; Melhem, Hassan; Vosbeck, Jürg; Cathomas, Gieri; Heigl, Andres; Heim, Markus H; Burri, Emanuel; Mertz, Kirsten D; Niess, Jan Hendrik; Kollmar, Otto; Zech, Christoph J; Ivanek, Robert; Duthaler, Urs; ... (2022). Stimulatory MAIT cell antigens reach the circulation and are efficiently metabolised and presented by human liver cells. Gut, 71(12), pp. 2526-2538. BMJ Publishing Group 10.1136/gutjnl-2021-324478
Bührer, Elias D; Amrein, Michael A; Forster, Stefan; Isringhausen, Stephan; Schürch, Christian M; Bhate, Salil S; Brodie, Tess; Zindel, Joel; Stroka, Deborah; Al Sayed, Mohamad; Nombela-Arrieta, César; Radpour, Ramin; Riether, Carsten; Ochsenbein, Adrian F (2022). Splenic red pulp macrophages provide a niche for CML stem cells and induce therapy resistance. Leukemia, 36(11), pp. 2634-2646. Springer Nature 10.1038/s41375-022-01682-2
Bayer, Julia; Stroka, Deborah; Kubes, Paul; Candinas, Daniel; Zindel, Joel (2022). Combination of Sterile Injury and Microbial Contamination to Model Post-surgical Peritoneal Adhesions in Mice. Bio-protocol, 12(16) 10.21769/BioProtoc.4491
Yarahmadov, Tural; Wang, Junhua; Sanches-Taltavull, Daniel; Rojas, Cristian A Alvarez; Brodie, Tess; Büchi, Isabel; Keogh, Adrian; Gottstein, Bruno; Stroka, Deborah; Beldi, Guido (2022). Primary Infection by E. multilocularis Induces Distinct Patterns of Cross Talk between Hepatic Natural Killer T Cells and Regulatory T Cells in Mice. Infection and immunity, 90(8), e0017422. American Society for Microbiology 10.1128/iai.00174-22
Dommann, Noëlle; Gavini, Jacopo; Sánchez-Taltavull, Daniel; Baier, Felix Alexander; Birrer, Fabienne; Loforese, Giulio; Candinas, Daniel; Stroka, Deborah (2022). LIM protein Ajuba promotes liver cell proliferation through its involvement in DNA replication and DNA damage control. FEBS letters, 596(14), pp. 1746-1764. FEBS Press 10.1002/1873-3468.14371
Melin, Nicolas; Yarahmadov, Tural; Sanchez-Taltavull, Daniel; Birrer, Fabienne E; Brodie, Tess M; Petit, Benoît; Felser, Andrea; Nuoffer, Jean-Marc; Montani, Matteo; Vozenin, Marie-Catherine; Herrmann, Evelyn; Candinas, Daniel; Aebersold, Daniel M; Stroka, Deborah (2022). A new mouse model of radiation-induced liver disease reveals mitochondrial dysfunction as an underlying fibrotic stimulus. JHEP reports, 4(7), p. 100508. Elsevier 10.1016/j.jhepr.2022.100508
Gavini, J; Leuenberger, D; Yarahmadov, T; Dommann, N; Keogh, A; Melin, N; Tschan, M; Nuoffer, J-M; Hertig, D; Zuber, B; Odriozola, A; Tombolini, R; Chrétien, M; Mbikay, M; Candinas, D; Stroka, D (2022). Intracellular Proprotein convertase subtilisin/kexin type 9: Recruitment and regulatory role in mitochondrial architecture and bioenergetic. British journal of surgery, 109(Supplement_3) Oxford University Press 10.1093/bjs/znac176.003
Zindel, Joel; Mittner, Jonas; Bayer, Julia; April-Monn, Simon L.; Kohler, Andreas; Nusse, Ysbrand; Dosch, Michel; Büchi, Isabel; Sanchez-Taltavull, Daniel; Dawson, Heather; Gomez de Agüero, Mercedes; Asahina, Kinji; Kubes, Paul; Macpherson, Andrew J.; Stroka, Deborah; Candinas, Daniel (2021). Intraperitoneal microbial contamination drives post-surgical peritoneal adhesions by mesothelial EGFR-signaling. Nature Communications, 12(1), p. 7316. Springer Nature 10.1038/s41467-021-27612-x
Wang, Zhong-Yi; Keogh, Adrian; Waldt, Annick; Cuttat, Rachel; Neri, Marilisa; Zhu, Shanshan; Schuierer, Sven; Ruchti, Alexandra; Crochemore, Christophe; Knehr, Judith; Bastien, Julie; Ksiazek, Iwona; Sánchez-Taltavull, Daniel; Ge, Hui; Wu, Jing; Roma, Guglielmo; Helliwell, Stephen B; Stroka, Deborah; Nigsch, Florian (2021). Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis. Scientific reports, 11(1), p. 19396. Springer Nature 10.1038/s41598-021-98806-y
Zwicky, Simone N.; Stroka, Deborah; Zindel, Joel (2021). Sterile Injury Repair and Adhesion Formation at Serosal Surfaces. Frontiers in immunology, 12, p. 684967. Frontiers Research Foundation 10.3389/fimmu.2021.684967
Ferro, Iolanda; Gavini, Jacopo; Gallo, Stefano; Bracher, Lisamaria; Landolfo, Marc; Candinas, Daniel; Keogh-Stroka, Deborah M.; Polacek, Norbert (2021). The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome in hepatocellular carcinoma. Autophagy, 18(1), pp. 191-203. Landes Bioscience 10.1080/15548627.2021.1922983
Baier, Felix Alexander; Sánchez-Taltavull, Daniel; Yarahmadov, Tural; Castellà, Cristina Gómez; Jebbawi, Fadi; Keogh, Adrian; Tombolini, Riccardo; Odriozola, Adolfo; Castro Dias, Mariana; Deutsch, Urban; Furuse, Mikio; Engelhardt, Britta; Zuber, Benoît; Odermatt, Alex; Candinas, Daniel; Keogh-Stroka, Deborah M. (2021). Loss of claudin-3 impairs hepatic metabolism, biliary barrier function and cell proliferation in the murine liver. Cellular and molecular gastroenterology and hepatology, 12(2), pp. 745-767. Elsevier 10.1016/j.jcmgh.2021.04.003
Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3
Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913
Sánchez-Taltavull, Daniel; Perkins, Theodore J; Dommann, Noelle; Melin, Nicolas; Keogh, Adrian; Candinas, Daniel; Stroka, Deborah; Beldi, Guido (2020). Bayesian correlation is a robust gene similarity measure for single-cell RNA-seq data. NAR genomics and bioinformatics, 2(1) Oxford University Press 10.1093/nargab/lqaa002
Gavini, Jacopo; Dommann, Noëlle; Jakob, Manuel O.; Keogh, Adrian; Bouchez, Laure C; Karkampouna, Sofia; Kruithof-de Julio, Marianna; Medova, Michaela; Zimmer, Yitzhak; Schläfli, Anna M; Tschan, Mario P.; Candinas, Daniel; Stroka, Deborah; Banz, Vanessa (2019). Verteporfin-induced lysosomal compartment dysregulation potentiates the effect of sorafenib in hepatocellular carcinoma. Cell death & disease, 10(10), p. 749. Springer Nature 10.1038/s41419-019-1989-z
Jakob, Manuel O.; Sánchez-Taltavull, Daniel; Yilmaz, Bahtiyar; Malinka, Thomas; Mooser, Catherine; Spari, Daniel; Salm, Lilian A.; Freiburghaus, Katrin; Pereyra, David; Hapfelmeier, Siegfried; Masoodi, Mojgan; Starlinger, Patrick; Stroka, Deborah; Tschan, Franziska; Candinas, Daniel; Gomez de Agüero, Mercedes; Beldi, Guido (19 September 2019). Compartmentalization of intestinal bacteria by hepatic ILC3s prevents infections after surgery (bioRxiv). Cold Spring Harbor Laboratory 10.1101/773150
Castro Dias, Mariana; Coisne, Caroline; Lazarevic, Ivana; Baden, Pascale; Hata, Masaki; Iwamoto, Noriko; Ferreira Francisco, David Miguel; Vanlandewijck, Michael; He, Liqun; Baier, Felix A.; Stroka, Deborah; Bruggmann, Rémy; Lyck, Ruth; Enzmann, Gaby; Deutsch, Urban; Betsholtz, Christer; Furuse, Mikio; Tsukita, Shoichiro; Engelhardt, Britta (2019). Publisher Correction: Claudin-3-deficient C57BL/6J mice display intact brain barriers. Scientific reports, 9(1), p. 10702. Springer Nature 10.1038/s41598-019-43511-0
Melhem, Hassan; Kallol, Sampada; Huang, Xiao; Lüthi, Michael; Ontsouka, Edgar; Keogh, Adrian; Stroka, Deborah; Thormann, Wolfgang; Schneider, Henning; Albrecht, Christiane (2019). Placental secretion of apolipoprotein A1 and E: the anti-atherogenic impact of the placenta. Scientific Reports, 9(1), p. 6225. Nature Publishing Group 10.1038/s41598-019-42522-1
Dosch, Michel; Zindel, Joël; Jebbawi, Fadi; Melin, Nicolas; Sanchez-Taltavull, Daniel; Stroka, Deborah; Candinas, Daniel; Beldi, Guido (2019). Connexin-43-dependent ATP release mediates macrophage activation during sepsis. eLife, 8 10.7554/eLife.42670
Mota Castro Dias, Mariana; Coisne, Caroline Marie; Lazarevic, Ivana; Baden, Pascale; Hata, Masaki; Iwamoto, Noriko; Francisco, David Miguel Ferreira; Vanlandewijck, Michael; He, Liqun; Baier, Felix Alexander; Keogh-Stroka, Deborah M.; Bruggmann, Rémy; Lyck, Ruth; Enzmann, Gaby; Deutsch, Urban; Betsholtz, Christer; Furuse, Mikio; Tsukita, Shoichiro; Engelhardt, Britta (2019). Claudin-3-deficient C57BL/6J mice display intact brain barriers. Scientific Reports, 9(1), p. 203. Nature Publishing Group 10.1038/s41598-018-36731-3
Górecka, Agata Joanna; Salemi, Souzan; Haralampieva, Deana; Moalli, Federica; Keogh-Stroka, Deborah M.; Candinas, Daniel; Eberli, Daniel; Brügger, Lukas (2018). Autologous transplantation of adipose-derived stem cells improves functional recovery of skeletal muscle without direct participation in new myofiber formation. Stem cell research & therapy, 9(1), p. 195. BioMed Central 10.1186/s13287-018-0922-1
Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurélie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6
Karkampouna, Sofia; van der Helm, Danny; Gray, Peter C; Chen, Lanpeng; Klima, Irena; Grosjean, Joël; Burgmans, Mark C; Farina-Sarasqueta, Arantza; Snaar-Jagalska, Ewa B; Keogh-Stroka, Deborah M.; Terracciano, Luigi; van Hoek, Bart; Schaapherder, Alexander F; Osanto, Susan; Thalmann, George; Verspaget, Hein W; Coenraad, Minneke J; Kruithof-de Julio, Marianna (2018). CRIPTO promotes an aggressive tumour phenotype and resistance to treatment in hepatocellular carcinoma. Journal of pathology, 245(3), pp. 297-310. Wiley 10.1002/path.5083
Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0
Melin, Nicolas; Sánchez Taltavull, Daniel; Petit, B.; Herman, E.; Zimmer, Yitzhak; Candinas, Daniel; Vozenin, M.C.; Aebersold, Daniel; Keogh-Stroka, Deborah M. (2018). SP-0330: Science slam: Report back from ESTRO mobility grants biology: Development of a radiation induced liver damage model. Radiotherapy and oncology, 127(Suppl. 1), S175-S176. Elsevier 10.1016/S0167-8140(18)30640-6
Kohler, Andreas; Büchi, Isabel; Melin, Nicolas; Bayer, F.; McCoy, Kathleen; Candinas, Daniel; Keogh-Stroka, Deborah M. (2018). The IL-33/ST2 axes contributes to hepatocyte proliferation and promotes development of hepatocellular carcinoma. HPB : official journal of The International Hepato-Pancreato-Biliary Association, 20(Suppl. 2), S261-S261. Elsevier 10.1016/j.hpb.2018.06.205
Melin, Nicolas; Fahrner, René; Keogh, Adrian; Medova, Michaela; Zimmer, Yitzhak; Aebersold, Daniel; Candinas, Daniel; Beldi, Guido; Keogh-Stroka, Deborah M. (2018). Direct and indirect hepatoprotective mechanism of CBLB502 a TLR5 agonist. Journal of hepatology, 68, S140-S141. Elsevier 10.1016/S0168-8278(18)30497-5
Loforese, Giulio; Malinka, Thomas; Keogh, Adrian; Baier, Felix; Simillion, Cedric André Marie; Montani, Matteo; Halazonetis, Thanos D; Candinas, Daniel; Keogh-Stroka, Deborah M. (2017). Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2. EMBO molecular medicine, 9(1), pp. 46-60. EMBO Press 10.15252/emmm.201506089
Francica, Paola; Nisa Hernandez, Lluis; Aebersold, Daniel; Langer, Rupert; Bladt, Friedhelm; Blaukat, Andree; Keogh-Stroka, Deborah M.; Martínez, María Rodríguez; Zimmer, Yitzhak; Medova, Michaela (2016). Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage-Induced Senescence Program in Gastric Cancer. Clinical cancer research, 22(21), pp. 5322-5336. American Association for Cancer Research 10.1158/1078-0432.CCR-15-2987
Lugli, Natalia; Kamileri, Irene; Keogh, Adrian; Malinka, Thomas; Sarris, Michalis E; Talianidis, Iannis; Schaad, Olivier; Candinas, Daniel; Halazonetis, Thanos D; Keogh-Stroka, Deborah M. (2016). R-spondin 1 and noggin facilitate expansion of resident stem cells from non-damaged gallbladders. EMBO reports, 17(5), pp. 769-779. Nature Publishing Group 10.15252/embr.201642169
Kudira, Ramesh; Malinka, Thomas; Kohler, Andreas; Dosch, Michel; Gomez de Agüero Tamargo, Maria de la Mercedes; Melin, Nicolas; Haegele, S; Starlinger, P; Maharjan, Niran; Saxena, Smita; Keogh, Adrian; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (2016). P2X1 regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration. Hepatology, 63(6), pp. 2004-2017. Wiley Interscience 10.1002/hep.28492
Kudira, Ramesh; Malinka, Thomas; Kohler, Andreas; Dosch, Michel; Gomez de Agüero Tamargo, Maria de la Mercedes; Melin, Nicolas; Haegele, S; Starlinger, P; Maharjan, Niran; Saxena, Smita; Keogh, Adrian; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (2016). P2X1 regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration (Unpublished). In: Keystone Symposium. Vancouver. 29.01.2016.
Studer, Peter; da Silva, C G; Revuelta Cervantes, J M; Mele, A; Csizmadia, E; Siracuse, J J; Damrauer, S M; Peterson, C R; Candinas, Daniel; Keogh-Stroka, Deborah M.; Ma, A; Bhasin, M; Ferran, C (2015). Significant lethality following liver resection in A20 heterozygous knockout mice uncovers a key role for A20 in liver regeneration. Cell death and differentiation, 22(12), pp. 2068-2077. Nature Publishing Group 10.1038/cdd.2015.52
Leiser, Dominic; Medova, Michaela; Mikami, Kei; Nisa Hernandez, Lluis; Keogh-Stroka, Deborah M.; Blaukat, Andree; Bladt, Friedhelm; Aebersold, Daniel; Zimmer, Yitzhak (2015). KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells. Molecular oncology, 9(7), pp. 1434-1446. Elsevier 10.1016/j.molonc.2015.04.001
Keogh-Stroka, Deborah M.; Keogh, Adrian; Vu, Dung; Fort, Alfredo; Stoffel, Michael Hubert; Kühni, Kathrin; Furer, Cynthia; Banz Wüthrich, Vanessa; Demarmels Biasiutti, Franziska; Lämmle, Bernhard; Candinas, Daniel; Neerman-Arbez, Marguerite (2014). In vitro rescue of FGA deletion by lentiviral transduction of an afibrinogenemic patient's hepatocytes. Journal of thrombosis and haemostasis, 12(11), pp. 1874-1879. Wiley-Blackwell 10.1111/jth.12714
Malinka, Thomas; Keogh, Adrian; Kudira, Ramesh; Moghadamrad, Sheida; McCoy, Kathleen; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (September 2014). Liver regeneration is not impacted in the absence of intestinal microbiota (Unpublished). In: Schweizerische Gesellschaft für Gastroenterologie (SGG) - Schweizerische Gesellschaft für Viszeralchirurgie (SGVC) Annual Congress. Interlaken. 11.-12.9.2014.
Kudira, Ramesh; Malinka, Thomas; Gomez de Agüero Tamargo, Maria de la Mercedes; Keogh, Adrian; Furer, Cynthia; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (September 2014). Secretion of IL-22 is modulated by CD39 and is required for liver regeneration post partial hepatectomy. In: Schweizerische Gesellschaft für Gastroenterologie (SGG) - Schweizerische Gesellschaft für Viszeralchirurgie (SGVC) Annual Congress. Interlaken. 11.-12.9.2014.
Malinka, Thomas; Keogh, Adrian; Kudira, Ramesh; Moghadamrad, Sheida; McCoy, Kathleen; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (September 2014). Travel Award: Liver regeneration is not impacted in the absence of intestinal microbiota (Unpublished). In: Schweizerische Gesellschaft für Gastroenterologie (SGG) - Schweizerische Gesellschaft für Viszeralchirurgie (SGVC) Annual Congress. Interlaken. 11.-12.9.2014.
Kudira, Ramesh; Malinka, Thomas; Gomez de Agüero Tamargo, Maria de la Mercedes; Keogh, Adrian; Furer, Cynthia; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (September 2014). Travel Award: Secretion of IL-22 is modulated by CD39 and is required for liver regeneration post partial hepatectomy (Unpublished). In: Schweizerische Gesellschaft für Gastroenterologie (SGG) - Schweizerische Gesellschaft für Viszeralchirurgie (SGVC) Annual Congress. Interlaken. 11.-12.09.2014.
Fahrner, René; Trochsler, Markus; Corazza, Nadia; Graubardt, Nadine; Keogh, Adrian; Candinas, Daniel; Brunner, Thomas; Keogh-Stroka, Deborah M.; Beldi, Guido (2014). Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand on NK Cells Protects From Hepatic Ischemia-Reperfusion Injury. Transplantation, 97(11), pp. 1102-1109. Lippincott Williams & Wilkins 10.1097/TP.0000000000000101
Balmer, Maria Luisa; Slack, Emma; De Gottardi, Andrea; Lawson, Melissa; Hapfelmeier, Siegfried Hektor; Miele, Luca; Grieco, Antonio; Van Vlierberghe, Hans; Fahrner, René; Patuto, Nicola; Bernsmeier, Christine; Ronchi, Francesca; Wyss, Madeleine; Keogh-Stroka, Deborah M.; Dickgreber, Nina; Heim, Markus H; McCoy, Kathy D; Macpherson, Andrew (2014). The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota. Science translational medicine, 6(237), 237ra66. American Association for the Advancement of Science 10.1126/scitranslmed.3008618
Fahrner, René; Patsenker, Eleanora; De Gottardi, Andrea; Stickel, Felix; Montani, Matteo; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (2014). Elevated liver regeneration in response to pharmacological reduction of elevated portal venous pressure by terlipressin after partial hepatectomy. Transplantation, 97(9), pp. 892-900. Lippincott Williams & Wilkins 10.1097/TP.0000000000000045
Malinka, Thomas; Keogh, Adrian; Kudira, Ramesh; Moghadamrad, Sheida; McCoy, Kathleen; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (May 2014). Liver regeneration is not impacted in the absence of intestinal microbiota. (Unpublished). In: Annual meeting of the Swiss Surgical Society. Bern. 21.-23.05.2014.
Kim-Fuchs, Corina; Winterhalder, Sebastian; Winter, Annja; Malinka, Thomas; Born, Diana; Schäfer, Stephan; Keogh-Stroka, Deborah M.; Gloor, Beat; Candinas, Daniel; Angst, Eliane (2014). The Silencing of N-myc Downstream-Regulated Gene-1 in an Orthotopic Pancreatic Cancer Model Leads to More Aggressive Tumor Growth and Metastases. Digestive surgery, 31(2), pp. 135-142. Karger 10.1159/000363065
Edelmann, Simone; Fahrner, René; Malinka, Thomas; Song, Bryan H.; Keogh-Stroka, Deborah M.; Mermod, Nicolas (2014). Nuclear Factor I-C acts as a regulator of hepatocyte proliferation at the onset of liver regeneration. Liver international, 35(4), pp. 1185-1194. Blackwell Munksgaard 10.1111/liv.12697
Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151
Portmann, Simone; Fahrner, René; Lechleiter, Antje; Keogh, Adrian; Overney, Sarah; Lämmle, Alexander; Mikami, Kei; Montani, Matteo; Tschan, Mario; Candinas, Daniel; Keogh-Stroka, Deborah M. (2013). Antitumor effect of SIRT1 inhibition in human HCC tumor models in vitro and in vivo. Molecular cancer therapeutics, 12(4), pp. 499-508. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-12-0700
Kudira, Ramesh; Breu, Karin; Keogh, Adrian; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (March 2013). Extracellular nucleotides modulate the secretion of IL-22 by hepatic innate lymphoid cells. In: World immune regulation meeting Davos. Davos. 13.-16.3.2013.
Graubardt, Nadine; Fahrner, René; Trochsler, Markus; Keogh, Adrian; Breu, Karin; Furer, Cynthia; Keogh-Stroka, Deborah M.; Robson, Simon C.; Slack, Emma; Candinas, Daniel; Beldi, Guido (2013). Promotion of liver regeneration by natural killer cells in a murine model is dependent on extracellular adenosine triphosphate phosphohydrolysis. Hepatology, 57(5), pp. 1969-1979. Wiley Interscience 10.1002/hep.26008
Graubardt, N; Fahrner, R; Keogh, A; Stroka, D; Candinas, D; Beldi, G (2012). Promotion of liver regeneration by NK cells in mice is dependent upon extracellular ATP phosphohydrolysis. In: Jahreskongress SGC Davos.
Laemmle, Alexander; Lechleiter, Antje; Roh, Vincent; Schwarz, Christa; Portmann, Simone; Furer, Cynthia; Keogh, Adrian; Tschan, Mario P; Candinas, Daniel; Vorburger, Stephan A; Stroka, Deborah (2012). Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions. PLoS ONE, 7(3), e33433. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0033433
Angst, Eliane; Dawson, David W; Stroka, Deborah; Gloor, Beat; Park, Jenny; Candinas, Daniel; Reber, Howard A; Hines, O Joe; Eibl, Guido (2011). N-myc downstream regulated gene-1 expression correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in vivo. Surgery, 149(5), pp. 614-24. New York, N.Y.: Elsevier 10.1016/j.surg.2010.11.002
Studer, P; da Silva, C; Csizmadia, E; Mennicke, M; Inderbitzin, D; Stroka, D; Candinas, D; Ferran, C (2011). Partial liver resection reveals a distinct phenotype in A20 heterozygote mice. In: 98. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Genf, Switzerland. 25.-27.5.2011.
Piguet, Anne-Christine; Stroka, Deborah; Zimmermann, Arthur; Dufour, Jean-François (2010). Hypoxia aggravates non-alcoholic steatohepatitis in mice lacking hepatocellular PTEN. Clinical science, 118(6), pp. 401-10. London: Portland 10.1042/CS20090313
Tschan, Mario P; Shan, Deborah; Laedrach, Judith; Eyholzer, Marianne; Leibundgut, Elisabeth Oppliger; Baerlocher, Gabriela M; Tobler, Andreas; Stroka, Deborah; Fey, Martin F (2010). NDRG1/2 expression is inhibited in primary acute myeloid leukemia. Leukemia research, 34(3), pp. 393-8. Amsterdam: Elsevier 10.1016/j.leukres.2009.08.037
Patsenker, E; Wilkens, L; Banz, V; Osterreicher, C H; Weimann, R; Eisele, S; Keogh, A; Stroka, D; Zimmermann, A; Stickel, F (2010). The alphavbeta6 integrin is a highly specific immunohistochemical marker for cholangiocarcinoma. Journal of hepatology, 52(3), pp. 362-9. Amsterdam: Elsevier 10.1016/j.jhep.2009.12.006
TROCHSLER, M; FAHRNER, R; GRAUBARDT, N; KEOGH, A; CORAZZA, N; STROKA, D; CANDINAS, D; BELDI, G (2010). TRAIL expression on NK cells attenuates hepatic ischemia-reperfusion injury in mice. In: Best Poster Prize.
Wampfler, Julian; Tschan, Mario P; Shan, Deborah; Laemmle, Alexander; Leibundgut, Elisabeth O; Baerlocher, Gabriela M; Stroka, Deborah; Fey, Martin F; Britschgi, Christian (2009). SIRT1 is downregulated during neutrophil differentiation of acute promyelocytic leukaemia cells. British journal of haematology, 146(3), pp. 337-41. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2009.07749.x
Banz, Vanessa M; Medová, Michaela; Keogh, Adrian; Furer, Cynthia; Zimmer, Yitzhak; Candinas, Daniel; Stroka, Deborah (2009). Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3beta. Biochimica et biophysica acta - molecular cell research, 1793(10), pp. 1597-603. New York, N.Y.: Elsevier 10.1016/j.bbamcr.2009.08.002
Wagner, Markus; Roh, Vincent; Strehlen, Michael; Laemmle, Alexander; Stroka, Deborah; Egger, Bernhard; Trochsler, Markus; Hunt, Kelly K; Candinas, Daniel; Vorburger, Stephan A (2009). Effective treatment of advanced colorectal cancer by rapamycin and 5-FU/oxaliplatin monitored by TIMP-1. Journal of gastrointestinal surgery, 13(10), pp. 1781-90. New York, N.Y.: Springer-Verlag 10.1007/s11605-009-0948-x
Monastyrskaya, Katia; Tschumi, Fabian; Babiychuk, Eduard B; Stroka, Deborah; Draeger, Annette (2008). Annexins sense changes in intracellular pH during hypoxia. Biochemical journal, 409(1), pp. 65-75. London: Portland Press 10.1042/BJ20071116
Roh, V; Laemmle, A; Von Holzen, U; Stroka, D; Dufour, Jean-François; Hunt, K K; Candinas, D; Vorburger, S A (2008). Dual induction of PKR with E2F-1 and IFN-alpha to enhance gene therapy against hepatocellular carcinoma. Cancer gene therapy, 15(10), pp. 636-44. New York, N.Y.: Nature Publishing Group 10.1038/cgt.2008.34
Piguet, Anne-Christine; Semela, David; Keogh, Adrian; Wilkens, Ludwig; Stroka, Deborah; Stoupis, Christoforos; St-Pierre, Marie V; Dufour, Jean-François (2008). Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma. Journal of hepatology, 49(1), pp. 78-87. Amsterdam: Elsevier 10.1016/j.jhep.2008.03.024
Quarta, Mattia; Stroka, Deborah; Keogh, Adrian; Sidler, Daniel; Avital, Itzhak; Gloor, Beat; Muraca, Maurizio; Candinas, Daniel; Inderbitzin, Daniel (2008). Multiparameter flow cytometry characterization of MHC class I negative mouse bone marrow cells. Medical science monitor, 14(12), BR286-93. Warszawa: Medical Science International
Inderbitzin, D; Quarta, M; Keogh, A; Sidler, D; Gloor, B; Stroka, D; Candinas, D (2007). Phenotypic characterization of the MHC-1 negative mouse bone marrow compartment: A potential source for adult liver committed stem cells. Gastroenterology(132), p. 889. Philadelphia, Pa.: Elsevier
Keogh, A; Gass, M; Candinas, D; Stroka, D (2007). Up-regulation of A20, an anti-apoptotic protein, is part of the protective response to hypoxic stress in the liver. Journal of hepatology, 46(46), S114. Amsterdam: Elsevier 10.1016/S0168-8278(07)61883-2
Peyer, Anne-Kathrin; Jung, Diana; Beer, Markus; Gnerre, Carmela; Keogh, Adrian; Stroka, Deborah; Zavolan, Mihaela; Meyer, Urs-A (2007). Regulation of human liver delta-aminolevulinic acid synthase by bile acids. Hepatology, 46(6), pp. 1960-70. Hoboken, N.J.: Wiley Interscience 10.1002/hep.21879
Keogh-Stroka, Deborah M.; Trochsler, M; Hlushchuk, R; Baum, O; Candinas, Daniel; Dufour, Jean-François; Djonov, V (2007). Sinusoidal duplication by intussusception is an early event in liver regeneration after partial hepatectomy. Journal of hepatology, 46(46), S146. Amsterdam: Elsevier 10.1016/S0168-8278(07)61974-6
Piguet, A; Ledermann, C; Zimmermann, A; Keogh-Stroka, Deborah M.; Dufour, Jean-François (2007). Hypoxia worsens non-alcoholic steatohepatitis. Journal of hepatology, 46(46), S10. Amsterdam: Elsevier 10.1016/S0168-8278(07)61616-X
Plock, Jan; Frese, Steffen; Keogh, Adrian; Bisch-Knaden, Sonja; Ayuni, Erick; Corazza, Nadia; Weikert, Christian; Jakob, Stephan; Erni, Dominique; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel; Stroka, Deborah (2007). Activation of non-ischemic, hypoxia-inducible signalling pathways up-regulate cytoprotective genes in the murine liver. Journal of hepatology, 47(4), pp. 538-45. Amsterdam: Elsevier 10.1016/j.jhep.2007.04.016
Sibold, Sonja; Roh, Vincent; Keogh, Adrian; Studer, Peter; Tiffon, Céline; Angst, Eliane; Vorburger, Stephan A; Weimann, Rosemarie; Candinas, Daniel; Stroka, Deborah (2007). Hypoxia increases cytoplasmic expression of NDRG1, but is insufficient for its membrane localization in human hepatocellular carcinoma. FEBS letters, 581(5), pp. 989-94. Amsterdam: Elsevier 10.1016/j.febslet.2007.01.080
Keogh-Stroka, Deborah M.; Plock, Jan Alexander; Beldi, Guido; Frese, Steffen R.; Keogh, Adrian; Bisch-Knaden, Sonja Maria; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel (2006). Temporary hypoxic stress protects the liver from Fas-mediated apoptosis and ischemia reperfusion injury. In: 93. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Lugano, Switzerland. 21.-23.6.2006.
