Candarlioglu, Pelin L; Dal Negro, Gianni; Hughes, David; Balkwill, Frances; Harris, Kate; Screen, Hazel; Morgan, Hywel; David, Rhiannon; Beken, Sonja; Guenat, Olivier; Rowan, Wendy; Amour, Augustin (2022). Organ-on-a-chip: current gaps and future directions. Biochemical Society transactions, 50(2), pp. 665-673. Portland Press 10.1042/BST20200661
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As an emerging hot topic of the last decade, Organ on Chip (OoC) is a new technology that is attracting interest from both basic and translational scientists. The Biochemical Society, with its mission of supporting the advancement of science, with addressing grand challenges that have societal impact, has included OoC into their agenda to review the current state of the art, bottlenecks and future directions. This conference brought together representatives of the main stakeholders in the OoC field including academics, end-users, regulators and technology developers to discuss and identify requirements for this new technology to deliver on par with the expectations and the key challenges and gaps that still need to be addressed to achieve robust human-relevant tools, able to positively impact decision making in the pharmaceutical industry and reduce overreliance on poorly predictive animal models.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research 10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Organs-on Chip Technologies |
UniBE Contributor: |
Guenat, Olivier Thierry |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
0300-5127 |
Publisher: |
Portland Press |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
20 Apr 2022 09:38 |
Last Modified: |
05 Dec 2022 16:19 |
Publisher DOI: |
10.1042/BST20200661 |
PubMed ID: |
35437569 |
Uncontrolled Keywords: |
drug discovery and design organ on chip translational science |
BORIS DOI: |
10.48350/169390 |
URI: |
https://boris.unibe.ch/id/eprint/169390 |
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