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van Os, Lisette; Yeoh, Wen Jie; Witz, Guillaume; Ferrari, Dario; Krebs, Philippe; Chandorkar, Yashoda; Zeinali, Soheila; Sengupta, Arunima; Guenat, Olivier (2023). Immune cell extravasation in an organ-on-chip to model lung inflammation. European journal of pharmaceutical sciences, 187, p. 106485. Elsevier 10.1016/j.ejps.2023.106485
Deletis, Vedran; Shils, Jay; Anso, Juan; Villar Ortega, Eduardo; Marchal-Crespo, Laura; Buetler, Karin A; Raabe, Andreas; Seidel, Kathleen (2023). Effects of 10-kHz Subthreshold Stimulation on Human Peripheral Nerve Activation. Neuromodulation: technology at the neural interface, 26(3), pp. 614-619. Elsevier 10.1016/j.neurom.2022.04.051
Ferrari, Dario; Sengupta, Arunima; Heo, Lyong; Pethö, Laszlo; Michler, Johann; Geiser, Thomas; de Jesus Perez, Vinicio A; Kuebler, Wolfgang M; Zeinali, Soheila; Guenat, Olivier T (2023). Effects of biomechanical and biochemical stimuli on angio- and vasculogenesis in a complex microvasculature-on-chip. iScience, 26(3), p. 106198. Elsevier 10.1016/j.isci.2023.106198
Sengupta, Arunima; Dorn, Aurélien; Jamshidi, Mohammad; Schwob, Magali; Hassan, Widad; De Maddalena, Lea Lara; Hugi, Andreas; Stucki, Andreas O.; Dorn, Patrick; Marti, Thomas M.; Wisser, Oliver; Stucki, Janick D.; Krebs, Tobias; Hobi, Nina; Guenat, Olivier T. (2023). A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip. Frontiers in Pharmacology, 14, p. 1114739. Frontiers 10.3389/fphar.2023.1114739
Zamprogno, Pauline; Schulte, Jan; Ferrari, Dario; Rechberger, Karin; Sengupta, Arunima; van Os, Lisette; Weber, Tobias; Zeinali, Soheila; Geiser, Thomas; Guenat, Olivier T. (2023). Lung-on-a-Chip Models of the Lung Parenchyma. Advances in experimental medicine and biology, 1413, pp. 191-211. Springer 10.1007/978-3-031-26625-6_10
Nizamoglu, Mehmet; Joglekar, Mugdha M.; Almeida, Catharina R.; Larsson Callerfelt, Anna-Karin; Dupin, Isabelle; Guenat, Olivier T.; Henrot, Pauline; van Os, Lisette; Otero, Jorge; Elowsson, Linda; Farre, Ramon; Burgess, Janette K. (2023). Innovative three-dimensional models for understanding mechanisms underlying lung diseases: powerful tools for translational research. European respiratory review, 32(169), p. 230042. European Respiratory Society 10.1183/16000617.0042-2023
van Os, Lisette; Engelhardt, Britta; Guenat, Olivier T. (2023). Integration of immune cells in organs-on-chips: a tutorial. Frontiers in Bioengineering and Biotechnology, 11, p. 1191104. Frontiers Media 10.3389/fbioe.2023.1191104
Sengupta, Arunima; Roldan, Nuria; Kiener, Mirjam; Froment, Laurène; Raggi, Giulia; Imler, Theo; de Maddalena, Lea; Rapet, Aude; May, Tobias; Carius, Patrick; Schneider-Daum, Nicole; Lehr, Claus-Michael; Kruithof-de Julio, Marianna; Geiser, Thomas; Marti, Thomas; Stucki, Janick D.; Hobi, Nina; Guenat, Olivier T (2022). A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip System. Frontiers in toxicology, 4(840606), pp. 1-18. Frontiers Media S.A. 10.3389/ftox.2022.840606
Candarlioglu, Pelin L; Dal Negro, Gianni; Hughes, David; Balkwill, Frances; Harris, Kate; Screen, Hazel; Morgan, Hywel; David, Rhiannon; Beken, Sonja; Guenat, Olivier; Rowan, Wendy; Amour, Augustin (2022). Organ-on-a-chip: current gaps and future directions. Biochemical Society transactions, 50(2), pp. 665-673. Portland Press 10.1042/BST20200661
Zeinali, S.; Rechberger, K. F.; Dubey, C.; Gashi, R.; Marti, T.; Dorn, P.; Guenat, O. T. (April 2022). Metastasis-on-chip: 3D human microvasculature network to study extravasation dynamics of lung cancer in vitro. Annals of oncology, 33(S2), S92-S92. Elsevier 10.1016/j.annonc.2022.02.159
van der Does, Anne M.; Guenat, Olivier T.; Geiser, Thomas; Hiemstra, Peter S. (2022). Lung-on-Chip. In: Westergren-Thorsson, Gunilla; Rolandsson Enes, Sara (eds.) 3D Lung Models for Regenerating Lung Tissue (pp. 133-151). Elsevier 10.1016/B978-0-323-90871-9.00001-2
Guenat, Olivier; Zamprogno, Pauline (2022). Ein biologisches Lungenmodell mit Forschungspotenzial. Biospektrum, 28(2), pp. 152-154. Springer 10.1007/s12268-022-1731-8
Zamprogno, Pauline; Thoma, Giuditta; Cencen, Veronika; Ferrari, Dario; Putz, Barbara; Michler, Johann; Fantner, Georg E.; Guenat, Olivier T. (2021). Mechanical properties of soft biological membranes for organ-on-a-chip assessed by bulge test and AFM. ACS biomaterials science & engineering, 7(7), pp. 2990-2997. American Chemical Society 10.1021/acsbiomaterials.0c00515
Zeinali, Soheila; Thompson, Emily K; Gerhardt, Holger; Geiser, Thomas; Guenat, Olivier Thierry T. (2021). Remodeling of an in vitro microvessel exposed to cyclic mechanical stretch. APL bioengineering, 5(2), 026102. AIP Publishing 10.1063/5.0010159
Zamprogno, Pauline; Wüthrich, Simon; Achenbach, Sven; Thoma, Giuditta; Stucki, Janick D.; Hobi, Nina; Schneider-Daum, Nicole; Lehr, klaus-michael; Huwer, Hanno; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier T. (2021). Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane. Communications biology, 4(1), p. 168. Springer Nature 10.1038/s42003-021-01695-0
Kiener, Mirjam; Roldan, Nuria; Machahua, Carlos; Sengupta, Arunima; Geiser, Thomas; Guenat, Olivier Thierry; Funke-Chambour, Manuela; Hobi, Nina; Kruithof-de Julio, Marianna (2021). Human-Based Advanced in vitro Approaches to Investigate Lung Fibrosis and Pulmonary Effects of COVID-19. Frontiers in medicine, 8(644678), p. 644678. Frontiers 10.3389/fmed.2021.644678
Tang, Ye; Kurth, Felix; Burr, Loïc; Petropoulos, Konstantinos; Migliorelli, Davide; Guenat, Olivier T.; Generelli, Silvia (2021). Nanocellulose aerogel inserts for quantitative lateral flow immunoassays. Biosensors & bioelectronics, 192(113491), pp. 1-9. Elsevier 10.1016/j.bios.2021.113491
Guenat, Olivier T.; Geiser, Thomas; Berthiaume, François (2020). Clinically Relevant Tissue Scale Responses as New Readouts from Organs-on-a-Chip for Precision Medicine. Annual review of analytical chemistry, 13(1), pp. 111-133. Annual Reviews 10.1146/annurev-anchem-061318-114919
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Krempaska, Kristina; Barnowski, Sandra; Gavini, Jacopo; Hobi, Nina; Ebener, Simone; Simillion, Cedric; Stokes, Andrea; Schliep, Ronja; Knudsen, Lars; Geiser, Thomas K.; Funke-Chambour, Manuela (2020). Correction to: Azithromycin has enhanced effects on lung fibroblasts from idiopathic pulmonary fibrosis (IPF) patients compared to controls. Respiratory research, 21(1), p. 29. BioMed Central 10.1186/s12931-020-1304-7
Tang, Ye; Petropoulos, Konstantinos; Kurth, Felix; Hui, Gao; Migliorelli, Davide; Guenat, Olivier; Generelli, Silvia (2020). Screen-Printed Glucose Sensors Modified with Cellulose Nanocrystals (CNCs) for Cell Culture Monitoring. Biosensors, 10(9), p. 125. MDPI 10.3390/bios10090125
Artzy-Schnirman, Arbel; Hobi, Nina; Schneider-Daum, Nicole; Guenat, Olivier T.; Lehr, Claus-Michael; Sznitman, Josué (2019). Advanced in vitro lung-on-chip platforms for inhalation assays: From prospect to pipeline. European journal of pharmaceutics and biopharmaceutics, 144, pp. 11-17. Elsevier 10.1016/j.ejpb.2019.09.006
Felder, Marcel Christian; Trueeb, Bettina; Stucki, Andreas Oliver; Borcard, Sarah; Stucki, Janick Daniel; Schnyder, Bruno; Geiser, Thomas; Guenat, Olivier Thierry (2019). Impaired Wound Healing of Alveolar Lung Epithelial Cells in a Breathing Lung-on-a-chip. Frontiers in Bioengineering and Biotechnology, 7(3), p. 3. Frontiers Media 10.3389/fbioe.2019.00003
Zamprogno, Pauline; Wüthrich, Simon; Achenbach, Sven; Stucki, Janick D.; Hobi, Nina; Schneider-Daum, Nicole; Lehr, Claus-Michael; Huwer, Hanno; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier T. (2019). Second-generation lung-on-a-chip array with a stretchable biological membrane (bioRxiv). Cold Spring Harbor Laboratory 10.1101/608919
Zeinali, Soheila; Bichsel, Colette A.; Hobi, Nina; Funke, Manuela; Marti, Thomas M.; Schmid, Ralph A.; Guenat, Olivier T.; Geiser, Thomas (2018). Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro. Angiogenesis, 21(4), pp. 861-871. Springer Netherlands 10.1007/s10456-018-9631-8
Mermoud, Yves; Felder, Marcel Christian; Stucki, Janick; Stucki, Andreas; Guenat, Olivier Thierry (2018). Microimpedance tomography system to monitor cell activity and membrane movements in a breathing lung-on-chip. Sensors and Actuators B: Chemical, 255(3), pp. 3647-3653. Elsevier 10.1016/j.snb.2017.09.192
Guenat, Olivier Thierry; Berthiaume, François (2018). Incorporating mechanical strain in organs-on-a-chip: Lung and skin. Biomicrofluidics, 12(4), 042207. American Institute of Physics 10.1063/1.5024895
Stucki, Janick; Hobi, Nina; Galimov, Artur; Stucki, Andreas; Schneider-Daum, Nicole; Lehr, Claus-Michael; Huwer, Hanno; Frick, Manfred; Funke-Chambour, Manuela; Geiser, Thomas; Guenat, Olivier Thierry (2018). Medium throughput breathing human primary cell alveolus-on-chip model. Scientific Reports, 8(1), p. 14359. Nature Publishing Group 10.1038/s41598-018-32523-x
Sfriso, Riccardo; Zhang, Shengye; Bichsel, Colette Andrea; Steck, Oliver Thomas; Despont, Alain; Guenat, Olivier Thierry; Rieben, Robert (2018). 3D artificial round section micro-vessels to investigate endothelial cells under physiological flow conditions. Scientific Reports, 8(1), p. 5898. Nature Publishing Group 10.1038/s41598-018-24273-7
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Bakirci, Ezgi; Guenat, Olivier Thierry; Hugi, Andreas; Ahmad, Sufian; Kohl, Sandro; Gantenbein, Benjamin (2017). Optimization of 3D printed hydrogels with primary cells for tissue engineering (Unpublished). In: AOSPine Masters Symposium-Novel and Emerging Technologies in Translational Medicine. Bern. 22 September 2017.
la Cour, Jakob B.; Generelli, Silvia; Barbe, Laurent; Guenat, Olivier Thierry (2016). Low-cost disposable ALT electrochemical microsensors for in-vitro hepatotoxic assessment. Sensors and Actuators B: Chemical, 228, pp. 360-365. Elsevier 10.1016/j.snb.2016.01.008
Wick, P.; Chortarea, S.; Guenat, Olivier Thierry; Roesslein, M.; Stucki, Janick; Hirn, S.; Petri-Fink, A.; Rothen-Rutishauser, B. (2015). In vitro-ex vivo model systems for nanosafety assessment. European Journal of Nanomedicine, 7(3), pp. 169-179. De Gruyter 10.1515/ejnm-2014-0049
Bichsel, Colette Andrea; Hall, Sean; Schmid, Ralph; Guenat, Olivier Thierry; Geiser, Thomas (2015). Primary human lung pericytes support and stabilize in-vitro perfusable microvessels. Tissue engineering. Part A, 21(15-16), p. 2166. Mary Ann Liebert 10.1089/ten.TEA.2014.0545
Stucki, Andreas; Stucki, Janick Daniel; Hall, Sean; Felder, Marcel Christian; Mermoud, Yves; Schmid, Ralph; Geiser, Thomas; Guenat, Olivier Thierry (2015). A lung-on-chip array with an integrated bio-inspired respiration mechanism. Lab on a chip, 15(5), pp. 1302-1310. Royal Society of Chemistry 10.1039/C4LC01252F
Ruppen, Janine; Wildhaber, Franziska Daniela; Strub, Christoph; Hall, Sean; Geiser, Thomas; Schmid, Ralph; Guenat, Olivier Thierry (2015). Towards personalized medicine: Chemosensitivity assays of patient lung cancer cell spheroids in a perfused microfluidic platform. Lab on a chip, 15(14), pp. 3076-3085. Royal Society of Chemistry 10.1039/C5LC00454C
Stucki, Janick; Guenat, Olivier Thierry (2015). A microfluidic bubble trap and oscillator. Lab on a chip, 15(23), pp. 4393-4397. Royal Society of Chemistry 10.1039/C5LC00592B
Maurer, Ellinor; Tschopp, Markus; Tappeiner, Christoph; Sallin, Pauline; Jazwinska, Anna; Enzmann, Volker (2014). Methylnitrosourea (MNU)-induced retinal degeneration and regeneration in the zebrafish: histological and functional characteristics. Journal of visualized experiments(92), e51909. MYJoVE Corporation 10.3791/51909
Felder, Marcel; Stucki, Andreas; Stucki, Janick; Geiser, Thomas; Guenat, Olivier Thierry (2014). The potential of microfluidic lung epithelial wounding: towards in vivo-like alveolar microinjuries. Integrative biology : quantitative biosciences from nano to macro, 6(12), pp. 1132-1140. Royal Society of Chemistry 10.1039/c4ib00149d
Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j
Das, Tamal; Meunier, Liliane; Barbe, Laurent; Provencher, Diane; Guenat, Olivier Thierry; Gervais, Thomas; Mes-Masson, Anne-Marie (2013). Empirical chemosensitivity testing in a spheroid model of ovarian cancer using a microfluidics-based multiplex platform. Biomicrofluidics, 7(1), p. 11805. American Institute of Physics 10.1063/1.4774309
Felder, Marcel; Sallin, Pauline; Barbe, Laurent; Haenni, Beat; Gazdhar, Amiq; Geiser, Thomas; Guenat, Olivier (2012). Microfluidic wound-healing assay to assess the regenerative effect of HGF on wounded alveolar epithelium. Lab on a chip, 12(3), pp. 640-6. Cambridge: Royal Society of Chemistry 10.1039/c1lc20879a
Peterhans, M; Gerber, N; Anderegg, S; Weber, S (2011). Joint visualization of navigated ultrasound and segmented computer tomography data for image-guided liver surgery. International Journal of Computer Assisted Radiology and Surgery, 6(Suppl. 1), S94-s95. Springer
Felder, Marcel; Sallin, Pauline; Barbe, Laurent; Gazdhar, Amiq; Geiser, Thomas; Guenat, Olivier Thierry (2011). Lung on Chip: In vitro HGF effects on injured alveolar A549 epithelial cells in microfluidic system. European respiratory journal, 38(Suppl 55), P4585. European Respiratory Society
Marconi, Emanuele; Schoeni, Anna; Barbe, Laurent; Gazdhar, Amiq; Geiser, Thomas; Guenat, Olivier Thierry (2011). Lung on a chip: Co-culture of alveolar epithelial cells and bone marrow derived stromal stem cells in a microfluidic system. European respiratory journal, 38(Suppl 55), P4585. European Respiratory Society
Danelon, Christophe; Terrettaz, Samuel; Guenat, Olivier; Koudelka, Milena; Vogel, Horst (2008). Probing the function of ionotropic and G protein-coupled receptors in surface-confined membranes. Methods, 46(2), pp. 104-15. San Diego, Calif.: Elsevier 10.1016/j.ymeth.2008.07.004
Generelli, Silvia; Jacquemart, Renaud; de Rooij, Nico F; Jolicoeur, Mario; Koudelka-Hep, Milena; Guenat, Olivier T (2008). Potentiometric platform for the quantification of cellular potassium efflux. Lab on a chip, 8(7), pp. 1210-5. Cambridge: Royal Society of Chemistry 10.1039/b801042k
Guenat, Olivier T; Generelli, Silvia; de Rooij, Nicolaas F; Koudelka-Hep, Milena; Berthiaume, François; Yarmush, Martin L (2006). Development of an array of ion-selective microelectrodes aimed for the monitoring of extracellular ionic activities. Analytical chemistry, 78(21), pp. 7453-60. Washington, D.C.: American Chemical Society 10.1021/ac0609733
Berdondini, L; van der Wal, P D; Guenat, O; de Rooij, N F; Koudelka-Hep, M; Seitz, P; Kaufmann, R; Metzler, P; Blanc, N; Rohr, S (2005). High-density electrode array for imaging in vitro electrophysiological activity. Biosensors & bioelectronics, 21(1), pp. 167-74. Barking, UK: Elsevier 10.1016/j.bios.2004.08.011
Guenat, O T; Boulard, G; Dufour, Jean-François; de Rooij, N F; Koudelka-Hep, M (2004). Development of a multifunctional platform for extra- and intracellular ionic activities recording. IEEE Engineering in Medicine and Biology Society conference proceedings, 2004, pp. 2546-2548. Piscataway, N.J.: IEEE Service Center
Guenat, OT; van der Schoot BH, ; Morf, WE; de Rooij NF, (2000). Triangle-programmed coulometric nanotitrations completed by continuous flow with potentiometric detection. Analytical chemistry, 72(7), pp. 1585-90. Washington, D.C.: American Chemical Society 10.1021/ac990488q
Guenat, Olivier; Morf, Werner; Van der Schoot, Bart; de Rooij, Nico (1998). Universal Coulometric Nanotitrators with Potentiometric Detection. Analytica Chimica Acta, 1998(361), pp. 261-272. Amsterdam: Elsevier 10.1016/S0003-2670(98)00034-8
