Guenat, Olivier; Zamprogno, Pauline (2022). Ein biologisches Lungenmodell mit Forschungspotenzial. Biospektrum, 28(2), pp. 152-154. Springer 10.1007/s12268-022-1731-8
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Guenat-Zamprogno2022_Article_EinBiologischesLungenmodellMit.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (609kB) | Preview |
Standard in vitro models fail to reproduce the complex cellular microenvironment of the human lung, whereas lung animal models poorly predict drug response in humans. A powerful alternative to model various aspects of the air-blood barrier is lung-on-chips using a thin and porous polymeric membrane. Researchers from the University of Bern have developed a new generation lung-on-chip that mimics an array of alveoli based on a biological membrane, on which patient cells are cultured, opening new potentials for lung research, drug screening and personalized medicine.
Item Type: |
Journal Article (Further Contribution) |
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Division/Institute: |
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Organs-on Chip Technologies 09 Interdisciplinary Units > Microscopy Imaging Center (MIC) |
UniBE Contributor: |
Guenat, Olivier Thierry, Zamprogno, Pauline Gil Véronique |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health 600 Technology > 620 Engineering |
ISSN: |
0947-0867 |
Publisher: |
Springer |
Language: |
German |
Submitter: |
Olivier Thierry Guenat |
Date Deposited: |
16 Jun 2022 08:55 |
Last Modified: |
15 Mar 2023 12:05 |
Publisher DOI: |
10.1007/s12268-022-1731-8 |
BORIS DOI: |
10.48350/170689 |
URI: |
https://boris.unibe.ch/id/eprint/170689 |
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